Hypereosinophilia with Concurrent Venous Thromboembolism: Clinical Features, Potential Risk Factors, and Short-term Outcomes in a Chinese Cohort.
Adult
Anticoagulants
/ therapeutic use
Drug Therapy, Combination
/ methods
Eosinophils
Female
Glucocorticoids
/ therapeutic use
Humans
Hypereosinophilic Syndrome
/ blood
Leukocyte Count
Male
Middle Aged
Pulmonary Embolism
/ blood
Recurrence
Retrospective Studies
Risk Factors
Time Factors
Venous Thromboembolism
/ blood
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
20 05 2020
20 05 2020
Historique:
received:
22
08
2019
accepted:
27
04
2020
entrez:
21
5
2020
pubmed:
21
5
2020
medline:
15
12
2020
Statut:
epublish
Résumé
Idiopathic hypereosinophilia (IHE) and hypereosinophilic syndrome (HES) are benign haematological disorders. Studies have suggested that venous thromboembolism (VTE) is a rare but sometimes fatal complication of hypereosinophilia; however, data are limited. We retrospectively analysed clinical features and short-term outcomes of 63 consecutive patients (82.5% men; mean age, 40.92 ± 10.89 years) with IHE or HES with concurrent VTE from January 1998 through December 2018. Risk factors for pulmonary embolism (PE) were explored by multivariate logistic analysis. DVT and/or PE was detected by imaging in all patients. Independent risk factors for PE were a body mass index of >24.1 kg/m
Identifiants
pubmed: 32433573
doi: 10.1038/s41598-020-65128-4
pii: 10.1038/s41598-020-65128-4
pmc: PMC7239859
doi:
Substances chimiques
Anticoagulants
0
Glucocorticoids
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
8359Références
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