The impact of frailty in major trauma in older patients.


Journal

Injury
ISSN: 1879-0267
Titre abrégé: Injury
Pays: Netherlands
ID NLM: 0226040

Informations de publication

Date de publication:
Jul 2020
Historique:
received: 21 07 2019
revised: 10 04 2020
accepted: 25 04 2020
pubmed: 22 5 2020
medline: 19 3 2021
entrez: 22 5 2020
Statut: ppublish

Résumé

As our population ages and increasing numbers of older patients experience major trauma it is important to understand factors that influence outcomes in this patient cohort. The aim of this study is to assess the impact of frailty in older patients who experience major trauma (Injury Severity Score (ISS) greater than 15). A retrospective cohort review using the national trauma registry data (Trauma Audit and Research Network) and an institutional database was carried out on all patients aged 60 years or older with an ISS> 15 who were treated at the regional Major Trauma Centre from 2014 to 2017 following major trauma. Frailty was assessed using the modified frailty index (mFI). Outcomes assessed included mortality, complications, hospital stay, functional outcome and discharge destination. 819 patients were included in the study. The most common mechanism of injury was fall from a height less than 2m (57.4%). 412 (51.3%) patients had a low frailty score, 280 (35%) had an intermediate frailty score and 110 (14%) had high frailty score. Increased frailty was associated with increased mortality at discharge (18.7%, 14.6% and 26.4% for low, intermediate and high frailty groups) and at one year (26.2%, 35.2% and 51%, respectively). Other predictors of mortality included male sex, age >90 years and the occurrence of a serious complication. Increasing frailty was also associated with an increased risk of serious complications including unplanned intubation, infection and progressive renal failure, and discharge to a destination other than home. This is the first study that has delineated the impact of frailty in older patients who experience major trauma and provides important information for patients, their families and healthcare providers. Future studies should focus on identifying care pathways that counteract the impact of frailty in this setting.

Identifiants

pubmed: 32434718
pii: S0020-1383(20)30392-2
doi: 10.1016/j.injury.2020.04.045
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1536-1542

Informations de copyright

Copyright © 2020 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest None.

Auteurs

M Pecheva (M)

Department of Trauma and Orthopaedic Surgery. Electronic address: mira.pecheva@doctors.org.uk.

M Phillips (M)

University of Cambridge.

P Hull (P)

Department of Trauma and Orthopaedic Surgery.

O'Leary R Carrothers A (OR)

Neurosciences Critical Care Unit, Addenbrooke's Hospital, Cambridge University Hospital NHS FT, Hills Road, CB20QQ.

J M Queally (JM)

Department of Trauma and Orthopaedic Surgery.

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