Improvement of dental prescribing practices using education and a prescribing tool: A pilot intervention study.


Journal

British journal of clinical pharmacology
ISSN: 1365-2125
Titre abrégé: Br J Clin Pharmacol
Pays: England
ID NLM: 7503323

Informations de publication

Date de publication:
01 2021
Historique:
received: 06 03 2020
revised: 06 05 2020
accepted: 07 05 2020
pubmed: 22 5 2020
medline: 29 7 2021
entrez: 22 5 2020
Statut: ppublish

Résumé

Antibiotic resistance is a global public health problem. Around 55% of dental antibiotic prescribing is deemed inappropriate. The aim of this multimodal interventional pilot study was to assess the effect on prescribing of education and a dentally designed prescribing website. Twenty-six dentists were recruited for the 12-week study using a pre-post design. Dentists self-recorded their prescribing of antibiotics, analgesics and anxiolytics for 6 weeks. After dentists were provided education and website access, they recorded their prescribing for a further 6 weeks. Four outcomes were measured comparing the prescribing before and after the intervention: (i) the number of inappropriate indications for which antibiotics were prescribed; (ii) the number of prescriptions; (iii) accuracy of the prescriptions according to the Australian therapeutic guidelines; and (iv) the confidence of practitioners towards the prescribing website. Participants were interviewed for feedback. There was a substantial reduction of 44.6% in the number of inappropriate indications for which antibiotics were prescribed after the intervention and a decrease of 40.5% in the total number of antibiotics. Paracetamol with codeine substantially reduced by 56.8%. For the 3 most commonly prescribed antibiotics (amoxicillin, phenoxymethylpenicillin and metronidazole), there was the improvement in the accuracy of the prescriptions ranging from 0-64.7 to 74.2-100%. This pilot study showed the intervention of targeted education and the prescribing tool was effective in improving dental prescribing, knowledge and confidence of practitioners, as well as providing an effective antibiotic stewardship tool. This context-specific intervention shows substantial promise for implementation into dental practice.

Identifiants

pubmed: 32436349
doi: 10.1111/bcp.14373
doi:

Substances chimiques

Anti-Bacterial Agents 0
Amoxicillin 804826J2HU

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

152-162

Subventions

Organisme : Australian Dental Research Foundation
ID : 332-2018
Organisme : Australian Government Research Training Program Scholarship
ID : 241616

Informations de copyright

© 2020 The British Pharmacological Society.

Références

Australian Commission of Safety and Quality in Health Care ACoSaQiHC. AURA 2019: third Australian report on antimicrobial use and resistance in human health. Sydney, ACSQHC; 2019.
Shehab N, Patel PR, Srinivasan A, Budnitz DS. Emergency department visits for antibiotic-associated adverse events. Clin Infect Dis. 2008;47(6):735-743.
World Health Organisation. Antimicrobial stewardship programmes in health-care facilities in low- and middle-income countries. A practical toolkit. Geneva; 2019.
Sanchez GV, Fleming-Dutra KE, Roberts RM, Hicks LA. Core elements of outpatient antibiotic stewardship. MMWR Recomm Rep. 2016;65(6):1-12.
Bye M, Whitten T, Holzbauer S. Antibiotic prescribing for dental procedures in community-associated Clostridium difficile cases, Minnesota, 2009-2015. Open Forum Infect Dis. 2017;4(suppl 1):S1.
Thornhill MH, Dayer MJ, Durkin MJ, Lockhart PB, Baddour LM. Risk of adverse reactions to Oral antibiotics prescribed by dentists. J Dent Res. 2019;98(10):1081-1087.
Liau I, Han J, Bayetto K, et al. Antibiotic resistance in severe odontogenic infections of the south Australian population: a 9-year retrospective audit. Aust Dent J. 2018;63(2):187-192.
Teoh LSK, Marino R, McCullough M. Part 1. Current prescribing trends of antibiotics by dentists in Australia from 2012 to 2016. Aust Dent J. 2018;63(3):329-337.
Marra F, George D, Chong M, Sutherland S, Patrick DM. Antibiotic prescribing by dentists has increased: why? J am Dent Assoc. 2016;147(5):320-327.
Thornhill MH, Dayer MJ, Durkin MJ, Lockhart PB, Baddour LM. Oral antibiotic prescribing by NHS dentists in England 2010-2017. Br Dent J. 2019;227(12):1044-1050.
Oral and Dental Expert Group. Therapeutic guidelines: Oral and dentalVersion. 2nd ed. Melbourne: Therapeutic Guidelines Limited; 2012.
Teoh L, Marino RJ, Stewart K, McCullough MJ. A survey of prescribing practices by general dentists in Australia. BMC Oral Health. 2019;19(1):193.
Teoh L, Stewart K, Marino RJ, McCullough MJ. Perceptions, attitudes and factors that influence prescribing by general dentists in Australia: a qualitative study. J Oral Pathol Med. 2019;48(7):647-654.
Teoh LSK, Marino R, McCullough M. Part 2. Current prescribing trends of dental non-antibacterial medicines in Australia from 2013 to 2016. Aust Dent J. 2018;63(3):338-346.
Hulme S, Bright D, Nielsen S. The source and diversion of pharmaceutical drugs for non-medical use: a systematic review and meta-analysis. Drug Alcohol Depend. 2018;186:242-256.
Koppen L, Suda KJ, Rowan S, McGregor J, Evans CT. Dentists' prescribing of antibiotics and opioids to Medicare part D beneficiaries: medications of high impact to public health. J am Dent Assoc. 2018;149(8):721-730.
Suda KJ, Durkin MJ, Calip GS, et al. Comparison of opioid prescribing by dentists in the United States and England. JAMA Netw Open. 2019;2(5):e194303.
Thornhill MH, Suda KJ, Durkin MJ, Lockhart PB. Is it time US dentistry ended its opioid dependence? J am Dent Assoc. 2019;150(10):883-889.
Schroeder AR, Dehghan M, Newman TB, Bentley JP, Park KT. Association of Opioid Prescriptions from Dental Clinicians for US adolescents and Young adults with subsequent opioid use and abuse. JAMA Intern Med. 2019;179(2):145-152.
Loffler C, Bohmer F. The effect of interventions aiming to optimise the prescription of antibiotics in dental care-a systematic review. PLoS One. 2017;12(11):e0188061.
Cohen J. Statistical power analysis for the behavioral sciences. 2nd ed. ed. Edition ed Hillsdale, New Jersey: Lawrence Erlbaum Assoc publishers; 1988.
Australian Government. Australian Bureau of Statistics. URL: "http://www.abs.gov.au/"
Australian Health Practitioner Regulation Agency. Dental Board of Australia - Registrant Data September 2018.
Mainjot A, D'Hoore W, Vanheusden A, Van Nieuwenhuysen JP. Antibiotic prescribing in dental practice in Belgium. Int Endod J. 2009;42(12):1112-1117.
Thompson W, Tonkin-Crine S, Pavitt SH, et al. Factors associated with antibiotic prescribing for adults with acute conditions: an umbrella review across primary care and a systematic review focusing on primary dental care. J Antimicrob Chemother. 2019;74(8):2139-2152.
Palmer NA, Dailey YM, Martin MV. Can audit improve antibiotic prescribing in general dental practice? Br Dent J. 2001;191(5):253-255.
Chate RA, White S, Hale LR, et al. The impact of clinical audit on antibiotic prescribing in general dental practice. Br Dent J. 2006;201(10):635-641.
Seager JM, Howell-Jones RS, Dunstan FD, Lewis MA, Richmond S, Thomas DW. A randomised controlled trial of clinical outreach education to rationalise antibiotic prescribing for acute dental pain in the primary care setting. Br Dent J. 2006;201(4):217-222. discussion 6
Elouafkaoui P, Young L, Newlands R, et al. An audit and feedback intervention for reducing antibiotic prescribing in general dental practice: the RAPiD cluster randomised controlled trial. PLoS Med. 2016;13(8):e1002115.
Gross AE, Hanna D, Rowan SA, Bleasdale SC, Suda KJ. Successful implementation of an antibiotic stewardship program in an academic dental practice. Open Forum Infect Dis. 2019;6(3):ofz067. https://doi.org/10.1093/ofid/ofz067
Moore PA, Ziegler KM, Lipman RD, Aminoshariae A, Carrasco-Labra A, Mariotti A. Benefits and harms associated with analgesic medications used in the management of acute dental pain: an overview of systematic reviews. J am Dent Assoc. 2018;149(4):256-265. e3.
Aminoshariae A, Kulild JC, Donaldson M, Hersh EV. Evidence-based recommendations for analgesic efficacy to treat pain of endodontic origin: a systematic review of randomized controlled trials. J am Dent Assoc. 2016;147(10):826-839.
Best AD, De Silva RK, Thomson WM, Tong DC, Cameron CM, De Silva HL. Efficacy of codeine when added to paracetamol (acetaminophen) and ibuprofen for relief of postoperative pain after surgical removal of impacted third molars: a double-blinded randomized control trial. J Oral Maxillofac Surg. 2017;75(10):2063-2069.
Daniels SE, Goulder MA, Aspley S, Reader S. A randomised, five-parallel-group, placebo-controlled trial comparing the efficacy and tolerability of analgesic combinations including a novel single-tablet combination of ibuprofen/paracetamol for postoperative dental pain. Pain. 2011;152(3):632-642.

Auteurs

Leanne Teoh (L)

Melbourne Dental School, University of Melbourne, Carlton, Victoria, Australia.

Kay Stewart (K)

Centre for Medicine Use and Safety, Monash University, Parkville, Victoria, Australia.

Rodrigo J Marino (RJ)

Melbourne Dental School, University of Melbourne, Carlton, Victoria, Australia.

Michael J McCullough (MJ)

Melbourne Dental School, University of Melbourne, Carlton, Victoria, Australia.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH