Preliminary study on Se-enriched Lentinula edodes mycelium as a proposal of new feed additive in selenium deficiency.


Journal

PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081

Informations de publication

Date de publication:
2020
Historique:
received: 20 12 2019
accepted: 05 05 2020
entrez: 22 5 2020
pubmed: 22 5 2020
medline: 13 8 2020
Statut: epublish

Résumé

The presence of selenium in European soil is low and this causes its deficiency in livestock and, in consequence, in humans. This study aimed to obtain Lentinula (L.) edodes mycelium with the maximum content of selenium. This species was used for experiment based on its documented medicinal properties. Calves were fed with selenium-enriched L. edodes mycelium, and serum selenium concentration, average daily weight gains and selected immune parameters were estimated. The selenium-enriched mushroom was found to be safe based on cytotoxicity tests (MTT and LDH tests) and for this reason it was used for further experiments. The mean quantity of selenium in the serum of calves fed with selenium-enriched L. edodes mycelium was significantly higher than that of control calves. Additionally, the calves fed with selenium-enriched L. edodes mycelium had higher body weight gains than those of control calves. White blood cell counts and subpopulations of lymphocytes in the experimental and control calves were within the reference range. The administration of L. edodes enriched with selenium had a beneficial effect on state of health of the calves.

Identifiants

pubmed: 32437465
doi: 10.1371/journal.pone.0233456
pii: PONE-D-19-35278
pmc: PMC7241721
doi:

Substances chimiques

Soil 0
Selenium H6241UJ22B

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0233456

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

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Auteurs

Bożena Muszyńska (B)

Department of Pharmaceutical Botany, Faculty of Pharmacy, Jagiellonian University Medical College, Krakow, Poland.

Ewelina Szacawa (E)

Department of Cattle and Sheep Diseases, National Veterinary Research Institute, Pulawy, Poland.

Dorota Bederska-Łojewska (D)

Department of Animal Nutrition and Feed Science, National Research Institute of Animal Production, Balice, Poland.

Katarzyna Dudek (K)

Department of Cattle and Sheep Diseases, National Veterinary Research Institute, Pulawy, Poland.

Bartosz Pomierny (B)

Department of Biochemical Toxicology, Faculty of Pharmacy, Jagiellonian University Medical College, Krakow, Poland.

Anna Włodarczyk (A)

Department of Pharmaceutical Botany, Faculty of Pharmacy, Jagiellonian University Medical College, Krakow, Poland.

Katarzyna Kała (K)

Department of Pharmaceutical Botany, Faculty of Pharmacy, Jagiellonian University Medical College, Krakow, Poland.

Jan Lazur (J)

Department of Pharmaceutical Botany, Faculty of Pharmacy, Jagiellonian University Medical College, Krakow, Poland.

Piotr Suchocki (P)

Department of Bioanalysis and Drug Analysis, Faculty of Pharmacy, Warsaw Medical University, Warszawa, Poland.

Bogusława Budziszewska (B)

Department of Biochemical Toxicology, Faculty of Pharmacy, Jagiellonian University Medical College, Krakow, Poland.

Dariusz Bednarek (D)

Department of Cattle and Sheep Diseases, National Veterinary Research Institute, Pulawy, Poland.

Marek Pieszka (M)

Department of Animal Nutrition and Feed Science, National Research Institute of Animal Production, Balice, Poland.

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Classifications MeSH