Effects of artemisinin on proliferation and apoptosis of human liver cancer HepG2 cells: A protocol of systematic review and meta-analysis.
Journal
Medicine
ISSN: 1536-5964
Titre abrégé: Medicine (Baltimore)
Pays: United States
ID NLM: 2985248R
Informations de publication
Date de publication:
May 2020
May 2020
Historique:
entrez:
24
5
2020
pubmed:
24
5
2020
medline:
17
6
2020
Statut:
ppublish
Résumé
This study will examine the effects of artemisinin on proliferation and apoptosis of human liver cancer HepG2 cells (HLCHG-2C). This study will systematically retrieve potential literatures in MEDLINE, Scopus, Web of Science, Cochrane Library, EMBASE, WANGFANG, and China National Knowledge Infrastructure from their initiation to the February 29, 2020. There are not limitations related to the language and publication time. All case-controlled studies (CCSs) or randomized controlled studies (RCSs) will be included in this study which investigated the effects of artemisinin on proliferation and apoptosis of HLCHG-2C. Two independent investigators will examine searched records, collect data from included studies, and will identify their methodological quality. Any divergences will be disentangled by discussion with another investigator. RevMan 5.3 software will be placed to pool the data and to carry out data analysis. This study will summarize all eligible studies to test the effects of artemisinin on proliferation and apoptosis of HLCHG-2C. The results of this study will exert evidence to examine the effects of artemisinin on proliferation and apoptosis of HLCHG-2C, and it may benefit further research, patients, and healthcare providers. INPLASY202040075.
Sections du résumé
BACKGROUND
BACKGROUND
This study will examine the effects of artemisinin on proliferation and apoptosis of human liver cancer HepG2 cells (HLCHG-2C).
METHODS
METHODS
This study will systematically retrieve potential literatures in MEDLINE, Scopus, Web of Science, Cochrane Library, EMBASE, WANGFANG, and China National Knowledge Infrastructure from their initiation to the February 29, 2020. There are not limitations related to the language and publication time. All case-controlled studies (CCSs) or randomized controlled studies (RCSs) will be included in this study which investigated the effects of artemisinin on proliferation and apoptosis of HLCHG-2C. Two independent investigators will examine searched records, collect data from included studies, and will identify their methodological quality. Any divergences will be disentangled by discussion with another investigator. RevMan 5.3 software will be placed to pool the data and to carry out data analysis.
RESULTS
RESULTS
This study will summarize all eligible studies to test the effects of artemisinin on proliferation and apoptosis of HLCHG-2C.
CONCLUSION
CONCLUSIONS
The results of this study will exert evidence to examine the effects of artemisinin on proliferation and apoptosis of HLCHG-2C, and it may benefit further research, patients, and healthcare providers.
SYSTEMATIC REVIEW REGISTRATION
BACKGROUND
INPLASY202040075.
Identifiants
pubmed: 32443376
doi: 10.1097/MD.0000000000020290
pii: 00005792-202005150-00092
pmc: PMC7254480
doi:
Substances chimiques
Anti-Infective Agents
0
Artemisinins
0
artemisinin
9RMU91N5K2
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e20290Références
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