Model Complexes Elucidate the Role of the Proximal Hydrogen-Bonding Network in Cytochrome P450s.

Cytochrome P-450 Enzyme System / chemistry Density Functional Theory Ferric Compounds / chemistry Hydrogen Bonding Models, Chemical Sulfhydryl Compounds / chemistry

Journal

Inorganic chemistry
ISSN: 1520-510X
Titre abrégé: Inorg Chem
Pays: United States
ID NLM: 0366543

Informations de publication

Date de publication:
15 Jun 2020
Historique:
pubmed: 27 5 2020
medline: 30 10 2020
entrez: 27 5 2020
Statut: ppublish

Résumé

Cytochrome (Cyt) P450s are an important class of enzymes with numerous functions in nature. The unique reactivity of these enzymes relates to their heme

Identifiants

DOI: 10.1021/acs.inorgchem.0c00245 PMID: 32452669
pubmed: 32452669
doi: 10.1021/acs.inorgchem.0c00245
doi:

Substances chimiques

Ferric Compounds 0
Sulfhydryl Compounds 0
Cytochrome P-450 Enzyme System 9035-51-2

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

8034-8043

Subventions

Organisme : NIGMS NIH HHS
ID : T32 GM008293
Pays : United States

Auteurs

Andrew P Hunt (AP)

Department of Chemistry and Department of Biophysics, University of Michigan, Ann Arbor, Michigan 48109-1055, United States.
ORCID: 0000-0003-0565-9050

Subhra Samanta (S)

Department of Chemistry and Department of Biophysics, University of Michigan, Ann Arbor, Michigan 48109-1055, United States.
ORCID: 0000-0003-4889-2370

Matthew R Dent (MR)

Department of Chemistry, University of Wisconsin, Madison, Wisconsin 53706, United States.
ORCID: 0000-0002-7704-4867

Michael W Milbauer (MW)

Department of Chemistry, University of Wisconsin, Madison, Wisconsin 53706, United States.

Judith N Burstyn (JN)

Department of Chemistry, University of Wisconsin, Madison, Wisconsin 53706, United States.

Nicolai Lehnert (N)

Department of Chemistry and Department of Biophysics, University of Michigan, Ann Arbor, Michigan 48109-1055, United States.
ORCID: 0000-0002-5221-5498

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Hémoprotéines › Cytochromes › Cytochrome P-450 enzyme system › Model Complexes Elucidate the Role of the...
questionsmedicales.fr › Disciplines des sciences naturelles › Physique › Physique nucléaire › Théorie quantique › Théorie de la fonctionnelle de la densité › Model Complexes Elucidate the Role of the...
questionsmedicales.fr › Produits chimiques inorganiques › Composés du fer › Composés du fer III › Model Complexes Elucidate the Role of the...
questionsmedicales.fr › Phénomènes chimiques › Liaison hydrogène › Model Complexes Elucidate the Role of the...
questionsmedicales.fr › Techniques d'investigation › Modèles théoriques › Modèles chimiques › Model Complexes Elucidate the Role of the...
questionsmedicales.fr › Composés chimiques organiques › Composés du soufre › Thiols › Model Complexes Elucidate the Role of the...