Outcomes of Minimally Invasive versus Open Surgery for Intermediate to High-grade Spondylolisthesis: A 10-Year Retrospective, Multicenter Experience.


Journal

Spine
ISSN: 1528-1159
Titre abrégé: Spine (Phila Pa 1976)
Pays: United States
ID NLM: 7610646

Informations de publication

Date de publication:
15 Oct 2020
Historique:
pubmed: 27 5 2020
medline: 20 1 2021
entrez: 27 5 2020
Statut: ppublish

Résumé

Retrospective cohort study. The primary objective of our study was to evaluate the surgical outcomes and complications of minimally invasive surgery (MIS) versus open surgery in the management of intermediate to high grade spondylolisthesis, and secondarily to compare the outcomes following MIS in-situ fusion versus MIS reduction and open in-situ fusion versus open reduction subgroups. High-grade spondylolisthesis is a relatively rare spine pathology with unknown prevalence. The optimal management and long-term prognosis of high-grade spondylolisthesis remain controversial. A multicenter, retrospective cohort study of adult patients who were surgically treated for grade II or higher lumbar or lumbosacral spondylolisthesis from January 2008 until February 2019, was conducted. A total of 57 patients were included in this study. Forty cases were treated with open surgery and 17 with MIS. Specifically, seven patients underwent MIS in-situ fusion, 11 patients open in-situ fusion, an additional 10 patients underwent MIS reduction, and 29 had open reduction. Patients who underwent open surgery had significantly better pain relief at short-term follow-up with no statistically significant difference in the rate of complications (25% vs. 35.2%, P = 0.44), as compared with MIS. The most common complications were related to instrumentation (17.7%), followed by neurological complications (14.5%), wound infection/dehiscence (6.5%), and post laminectomy syndrome (1.6%). The average follow-up time was 9.1 ± 6.2 months. In a subgroup comparison, the complication rate in the open in-situ fusion (36.3%) versus open reduction (20.6%) subgroup was non-significant (P = 0.42). However, complication rate in the MIS reduction group (55%) was significantly higher than MIS in-situ fusion (P = 0.03). MIS reduction is associated with a higher rate of complications in the management of grade II or higher lumbar or lumbosacral spondylolisthesis. The management of this complex pathology may be better addressed via traditional open surgery. 3.

Sections du résumé

STUDY DESIGN METHODS
Retrospective cohort study.
OBJECTIVE OBJECTIVE
The primary objective of our study was to evaluate the surgical outcomes and complications of minimally invasive surgery (MIS) versus open surgery in the management of intermediate to high grade spondylolisthesis, and secondarily to compare the outcomes following MIS in-situ fusion versus MIS reduction and open in-situ fusion versus open reduction subgroups.
SUMMARY OF BACKGROUND DATA BACKGROUND
High-grade spondylolisthesis is a relatively rare spine pathology with unknown prevalence. The optimal management and long-term prognosis of high-grade spondylolisthesis remain controversial.
METHODS METHODS
A multicenter, retrospective cohort study of adult patients who were surgically treated for grade II or higher lumbar or lumbosacral spondylolisthesis from January 2008 until February 2019, was conducted.
RESULTS RESULTS
A total of 57 patients were included in this study. Forty cases were treated with open surgery and 17 with MIS. Specifically, seven patients underwent MIS in-situ fusion, 11 patients open in-situ fusion, an additional 10 patients underwent MIS reduction, and 29 had open reduction. Patients who underwent open surgery had significantly better pain relief at short-term follow-up with no statistically significant difference in the rate of complications (25% vs. 35.2%, P = 0.44), as compared with MIS. The most common complications were related to instrumentation (17.7%), followed by neurological complications (14.5%), wound infection/dehiscence (6.5%), and post laminectomy syndrome (1.6%). The average follow-up time was 9.1 ± 6.2 months. In a subgroup comparison, the complication rate in the open in-situ fusion (36.3%) versus open reduction (20.6%) subgroup was non-significant (P = 0.42). However, complication rate in the MIS reduction group (55%) was significantly higher than MIS in-situ fusion (P = 0.03).
CONCLUSION CONCLUSIONS
MIS reduction is associated with a higher rate of complications in the management of grade II or higher lumbar or lumbosacral spondylolisthesis. The management of this complex pathology may be better addressed via traditional open surgery.
LEVEL OF EVIDENCE METHODS
3.

Identifiants

pubmed: 32453240
doi: 10.1097/BRS.0000000000003573
pii: 00007632-202010150-00016
doi:

Types de publication

Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

1451-1458

Références

Meyerding HW. Surgical fusion of the vertebral articular facets; technique and instruments employed. Surg Gynecol Obstet 1947; 84:50–54.
Kasliwal MK, Smith JS, Kanter A, et al. Management of high-grade spondylolisthesis. Neurosurg Clin N Am 2013; 24:275–291.
Haun DW, Kettner NW. Spondylolysis and spondylolisthesis: a narrative review of etiology, diagnosis, and conservative management. J Chiropr Med 2005; 4:206–217.
Acosta FL Jr, Ames CP, Chou D. Operative management of adult high-grade lumbosacral spondylolisthesis. Neurosurg Clin N Am 2007; 18:249–254.
Goyal N, Wimberley DW, Hyatt A, et al. Radiographic and clinical outcomes after instrumented reduction and transforaminal lumbar interbody fusion of mid and high-grade isthmic spondylolisthesis. J Spinal Disord Tech 2009; 22:321–327.
Passias PG, Poorman CE, Yang S, et al. Surgical treatment strategies for high-grade spondylolisthesis: a systematic review. Int J Spine Surg 2015; 9:50.
Transfeldt EE, Mehbod AA. Evidence-based medicine analysis of isthmic spondylolisthesis treatment including reduction versus fusion in situ for high-grade slips. Spine (Phila Pa 1976) 2007; 32: (19 suppl): S126–S129.
Archavlis E, Carvi y Nievas M. Comparison of minimally invasive fusion and instrumentation versus open surgery for severe stenotic spondylolisthesis with high-grade facet joint osteoarthritis. Eur Spine J 2013; 22:1731–1740.
Qin R, Liu B, Zhou P, et al. Minimally invasive versus traditional open transforaminal lumbar interbody fusion for the treatment of single-level spondylolisthesis grades 1 and 2: a systematic review and meta-analysis. World Neurosurg 2019; 122:180–189.
Rajakumar DV, Hari A, Krishna M, et al. Complete anatomic reduction and monosegmental fusion for lumbar spondylolisthesis of Grade II and higher: use of the minimally invasive “rocking” technique. Neurosurg Focus 2017; 43:E12.
Alzakri A, Labelle H, Hresko MT, et al. Restoration of normal pelvic balance from surgical reduction in high-grade spondylolisthesis. Eur Spine J 2019; 28:2087–2094.
Gandhoke GS, Kasliwal MK, Smith JS, et al. A multicenter evaluation of clinical and radiographic outcomes following high-grade spondylolisthesis reduction and fusion. Clin Spine Surg 2017; 30:E363–E369.
Karampalis C, Grevitt M, Shafafy M, et al. High-grade spondylolisthesis: gradual reduction using Magerl's external fixator followed by circumferential fusion technique and long-term results. Eur Spine J 2012; 21: (suppl): S200–S206.
Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 2004; 240:205–213.
Boxall D, Bradford DS, Winter RB, et al. Management of severe spondylolisthesis in children and adolescents. J Bone Joint Surg Am 1979; 61:479–495.
DeWald RL, Faut MM, Taddonio RF, et al. Severe lumbosacral spondylolisthesis in adolescents and children. Reduction and staged circumferential fusion. J Bone Joint Surg Am 1981; 63:619–626.
Lamartina C, Zavatsky JM, Petruzzi M, et al. Novel concepts in the evaluation and treatment of high-dysplastic spondylolisthesis. Eur Spine J 2009; 18: (suppl): 133–142.
Moller H, Hedlund R. Surgery versus conservative management in adult isthmic spondylolisthesis--a prospective randomized study: part 1. Spine (Phila Pa 1976) 2000; 25:1711–1715.
Muschik M, Zippel H, Perka C. Surgical management of severe spondylolisthesis in children and adolescents. Anterior fusion in situ versus anterior spondylodesis with posterior transpedicular instrumentation and reduction. Spine (Phila Pa 1976) 1997; 22:2036–2042. discussion 2043.
Pizzutillo PD, Hummer CD 3rd. Nonoperative treatment for painful adolescent spondylolysis or spondylolisthesis. J Pediatr Orthop 1989; 9:538–540.
Pizzutillo PD, Mirenda W, MacEwen GD. Posterolateral fusion for spondylolisthesis in adolescence. J Pediatr Orthop 1986; 6:311–316.
Kasliwal MK, Smith JS, Shaffrey CI, et al. Short-term complications associated with surgery for high-grade spondylolisthesis in adults and pediatric patients: a report from the scoliosis research society morbidity and mortality database. Neurosurgery 2012; 71:109–116.
Goldstein CL, Macwan K, Sundararajan K, et al. Perioperative outcomes and adverse events of minimally invasive versus open posterior lumbar fusion: meta-analysis and systematic review. J Neurosurg Spine 2016; 24:416–427.
Jin-Tao Q, Yu T, Mei W, et al. Comparison of MIS vs. open PLIF/TLIF with regard to clinical improvement, fusion rate, and incidence of major complication: a meta-analysis. Eur Spine J 2015; 24:1058–1065.
Labelle H, Mac-Thiong JM, Roussouly P. Spino-pelvic sagittal balance of spondylolisthesis: a review and classification. Eur Spine J 2011; 20: (suppl): 641–646.
Poussa M, Remes V, Lamberg T, et al. Treatment of severe spondylolisthesis in adolescence with reduction or fusion in situ: long-term clinical, radiologic, and functional outcome. Spine (Phila Pa 1976) 2006; 31:583–590. discussion 591-582.
Iyer S, Lenke LG, Nemani VM, et al. Variations in occipitocervical and cervicothoracic alignment parameters based on age: a prospective study of asymptomatic volunteers using full-body radiographs. Spine (Phila Pa 1976) 2016; 41:1837–1844.
Lak AM, Abunimer AM, Devi S, et al. Reduction versus in situ fusion for adult high-grade spondylolisthesis: a systematic review and meta-analysis. World Neurosurg 2020; 138:512–520.e2.

Auteurs

Asad M Lak (AM)

Computational Neurosciences Outcomes Center, Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

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