Hepatoprotective Effect of Apigenin Against Liver Injury via the Non-canonical NF-κB Pathway In Vivo and In Vitro.
Animals
Apigenin
/ pharmacology
Carbon Tetrachloride
/ toxicity
Cell Survival
/ drug effects
Chemical and Drug Induced Liver Injury
/ metabolism
Dose-Response Relationship, Drug
Hep G2 Cells
Humans
Hydrogen Peroxide
/ toxicity
Male
Mice
Mice, Inbred ICR
NF-kappa B
/ metabolism
Oxidative Stress
/ drug effects
Signal Transduction
/ drug effects
apigenin
inflammation
non-canonical NF-κB pathway
oxidative stress
Journal
Inflammation
ISSN: 1573-2576
Titre abrégé: Inflammation
Pays: United States
ID NLM: 7600105
Informations de publication
Date de publication:
Oct 2020
Oct 2020
Historique:
pubmed:
28
5
2020
medline:
16
7
2021
entrez:
28
5
2020
Statut:
ppublish
Résumé
Apigenin, a flavonoid found in many plants, has various biological properties. We aimed to investigate the anti-inflammatory and anti-oxidative activity of apigenin against carbon tetrachloride (CCl
Identifiants
pubmed: 32458347
doi: 10.1007/s10753-020-01238-5
pii: 10.1007/s10753-020-01238-5
doi:
Substances chimiques
NF-kappa B
0
Apigenin
7V515PI7F6
Hydrogen Peroxide
BBX060AN9V
Carbon Tetrachloride
CL2T97X0V0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1634-1648Subventions
Organisme : Natural Science Foundation of Jiangsu Province
ID : BK20180574
Organisme : Natural Science Foundation of Jiangsu Province
ID : BK20171064
Organisme : Technology Incubator Scheme (Social Programs) of Jiangning District
ID : 2018Ca12
Organisme : Research Foundation of Jiangsu Provincial Medical Youth Talent, the Project of Inviogorating Health Care through Science, Technology and Education
ID : QNRC2016858
Organisme : Nanjing Medical University Science Research and Development Foundation
ID : 2016NJMU013
Organisme : Natural Science Research Fund (General Program) for the Higher Education of Jiangsu Province of China
ID : 18KJB350005
Organisme : Zhenjiang City 2017 Science and Technology Innovation Fund
ID : SH2017043
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