Trends in the Use of Cardiac Imaging for Women with Newly Diagnosed Breast Cancer.


Journal

Journal of cardiovascular translational research
ISSN: 1937-5395
Titre abrégé: J Cardiovasc Transl Res
Pays: United States
ID NLM: 101468585

Informations de publication

Date de publication:
06 2020
Historique:
received: 18 01 2020
accepted: 05 05 2020
pubmed: 28 5 2020
medline: 21 10 2020
entrez: 28 5 2020
Statut: ppublish

Résumé

We investigated time trends and factors associated with the use of cardiac imaging among women with early-stage breast cancer prior to the initiation of treatment. Of 11,732 women ages 24-64, diagnosed with stage I-III breast cancer in 2006-2011, 2550 (22%) received anthracycline-based chemotherapy. Baseline cardiac imaging was used in 79% of patients receiving anthracyclines and increased over time. Of 2277 (20%) women who received non-anthracycline therapy, 16% received cardiac imaging. Women receiving cardiac imaging in non-anthracycline therapy group were more likely to have higher cardiovascular risk, as well as higher cancer stage and worse histological tumor grade suggesting that results of imaging might have influenced the choice of cancer therapy. Our findings indicate the need for cardio-oncology collaboration in identification and treatment of women at high risk for adverse oncology and cardiovascular outcomes.

Identifiants

pubmed: 32458402
doi: 10.1007/s12265-020-10023-6
pii: 10.1007/s12265-020-10023-6
doi:

Substances chimiques

Anthracyclines 0
Antibiotics, Antineoplastic 0

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

478-489

Subventions

Organisme : NIH HHS
ID : R01CA160671
Pays : United States
Organisme : National Institutes of Health (US)
ID : P30CA051008
Pays : International

Auteurs

Ana Barac (A)

MedStar Heart and Vascular Institute, Georgetown University, 110 Irving Street, NW, Ste. 1218, Washington, DC, 20010, USA. Ana.Barac@medstar.net.

Claudine Isaacs (C)

Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, USA.

Nawar M Shara (N)

Department of Biostatistics and Biomedical Informatics, MedStar Health Research Institute, Hyattsville, MD, USA.

Filipa Lynce (F)

Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, USA.

Sameer Desale (S)

Department of Biostatistics and Biomedical Informatics, MedStar Health Research Institute, Hyattsville, MD, USA.

Kevin Haynes (K)

HealthCore, Inc., Wilmington, DE, USA.

Arnold L Potosky (AL)

Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, USA.

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Classifications MeSH