Bacterial metabolism of bile acids promotes generation of peripheral regulatory T cells.
Amino Acid Sequence
Animals
Bacteria
/ metabolism
Bacteroides
/ metabolism
Bile Acids and Salts
/ chemistry
Colon
/ microbiology
Dendritic Cells
/ immunology
Female
Fermentation
Gastrointestinal Microbiome
Male
Mice
Mice, Inbred C57BL
Microbial Consortia
Nuclear Receptor Subfamily 1, Group F, Member 3
/ metabolism
Receptors, Cytoplasmic and Nuclear
/ metabolism
T-Lymphocytes, Regulatory
/ cytology
Journal
Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462
Informations de publication
Date de publication:
05 2020
05 2020
Historique:
received:
15
06
2019
accepted:
14
02
2020
entrez:
29
5
2020
pubmed:
29
5
2020
medline:
1
9
2020
Statut:
ppublish
Résumé
Intestinal health relies on the immunosuppressive activity of CD4
Identifiants
pubmed: 32461639
doi: 10.1038/s41586-020-2193-0
pii: 10.1038/s41586-020-2193-0
pmc: PMC7540721
mid: NIHMS1562317
doi:
Substances chimiques
Bile Acids and Salts
0
Nuclear Receptor Subfamily 1, Group F, Member 3
0
Receptors, Cytoplasmic and Nuclear
0
farnesoid X-activated receptor
0C5V0MRU6P
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
475-479Subventions
Organisme : NICHD NIH HHS
ID : DP2 HD101401
Pays : United States
Organisme : NIH HHS
ID : 1DP2HD101401-01
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM008283
Pays : United States
Organisme : NCI NIH HHS
ID : P30 CA008748
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI034206
Pays : United States
Organisme : NCI NIH HHS
ID : U54 CA209975
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM149438
Pays : United States
Organisme : Howard Hughes Medical Institute
Pays : United States
Commentaires et corrections
Type : CommentIn
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