CDK7 Mediates the Beta-Adrenergic Signaling in Thermogenic Brown and White Adipose Tissues.

Biological Sciences Cell Biology Endocrinology

Journal

iScience
ISSN: 2589-0042
Titre abrégé: iScience
Pays: United States
ID NLM: 101724038

Informations de publication

Date de publication:
26 Jun 2020
Historique:
received: 03 02 2020
revised: 31 03 2020
accepted: 11 05 2020
pubmed: 29 5 2020
medline: 29 5 2020
entrez: 29 5 2020
Statut: ppublish

Résumé

Cyclin-dependent kinases (CDKs) are emerging regulators of adipose tissue metabolism. Here we aimed to explore the role of CDK7 in thermogenic fat. We found that CDK7 brown adipose tissue (BAT)-specific knockout mice (Cdk7

Identifiants

pubmed: 32464595
pii: S2589-0042(20)30348-5
doi: 10.1016/j.isci.2020.101163
pmc: PMC7256631
pii:
doi:

Types de publication

Journal Article

Langues

eng

Pagination

101163

Informations de copyright

Copyright © 2020 The Author(s). Published by Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Interests The authors declare no competing interests.

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Auteurs

Honglei Ji (H)

Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.

Yizhe Chen (Y)

Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China.

Judit Castillo-Armengol (J)

Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.

René Dreos (R)

Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.

Catherine Moret (C)

Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.

Guy Niederhäuser (G)

Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.

Brigitte Delacuisine (B)

Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.

Isabel C Lopez-Mejia (IC)

Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.

Pierre-Damien Denechaud (PD)

Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland; Institut National de la Santé et de la Recherche Médicale (Inserm), UMR1048, Institute of Metabolic and Cardiovascular Diseases, Toulouse, France.

Lluis Fajas (L)

Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland; Institut National de la Santé et de la Recherche Médicale (Inserm), Languedoc Roussillon, France. Electronic address: lluis.fajas@unil.ch.

Classifications MeSH