Flame Figures in Linear Immunoglobulin A Bullous Dermatosis Secondary to Parvovirus B19 Infection.
Adrenal Cortex Hormones
/ therapeutic use
Anti-Allergic Agents
/ therapeutic use
Antibodies, Viral
/ blood
Eosinophils
/ drug effects
Erythema Infectiosum
/ diagnosis
Histamine Antagonists
/ therapeutic use
Host-Pathogen Interactions
Humans
Immunoglobulin M
/ blood
Linear IgA Bullous Dermatosis
/ drug therapy
Male
Middle Aged
Parvovirus B19, Human
/ immunology
Skin
/ drug effects
Treatment Outcome
Journal
The American Journal of dermatopathology
ISSN: 1533-0311
Titre abrégé: Am J Dermatopathol
Pays: United States
ID NLM: 7911005
Informations de publication
Date de publication:
01 Jan 2021
01 Jan 2021
Historique:
pubmed:
31
5
2020
medline:
7
10
2021
entrez:
31
5
2020
Statut:
ppublish
Résumé
Flame figures represent a characteristic but nondiagnostic histological finding in eosinophilic dermatoses. Some bullous autoimmune diseases with a predominant eosinophilic infiltrate, such as bullous pemphigoid, pemphigoid gestationis, and pemphigus vegetans, may show them. However, it is rare to find them in predominant neutrophilic bullous dermatoses such as linear immunoglobulin A. We present a 60-year-old man with a history of chronic urticaria, which presented a bullous disease after an acute parvovirus B19 infection. The histological findings showed an exceptional linear immunoglobulin A bullous dermatosis with an eosinophilic infiltrate in the dermis forming "flame figures." The clinical and histopathological findings for this entity may be identical to those of other dermatoses. For this reason, combining these findings with direct immunofluorescence analysis is essential for correct diagnosis of this bullous disease.
Identifiants
pubmed: 32472771
pii: 00000372-202101000-00012
doi: 10.1097/DAD.0000000000001690
doi:
Substances chimiques
Adrenal Cortex Hormones
0
Anti-Allergic Agents
0
Antibodies, Viral
0
Histamine Antagonists
0
Immunoglobulin M
0
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
60-62Informations de copyright
Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.
Déclaration de conflit d'intérêts
The authors declare no conflicts of interest.
Références
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