A cluster of SARS-CoV-2 infection among Italian tourists visiting India, March 2020.
Aged
Asymptomatic Infections
/ epidemiology
Betacoronavirus
/ genetics
COVID-19
Cluster Analysis
Coronavirus Infections
/ diagnosis
Critical Illness
Fatal Outcome
Female
Humans
India
/ epidemiology
Italy
/ ethnology
Male
Nasal Cavity
/ virology
Pandemics
Patient Acuity
Pharynx
/ virology
Pneumonia, Viral
/ diagnosis
RNA, Viral
/ analysis
Reverse Transcriptase Polymerase Chain Reaction
SARS-CoV-2
Travel
Contact - COVID-19 - India - SARS-CoV-2 - transmission
Journal
The Indian journal of medical research
ISSN: 0971-5916
Titre abrégé: Indian J Med Res
Pays: India
ID NLM: 0374701
Informations de publication
Date de publication:
May 2020
May 2020
Historique:
pubmed:
1
6
2020
medline:
14
7
2020
entrez:
1
6
2020
Statut:
ppublish
Résumé
A cluster of SARS-CoV-2 infection occurred among Italian tourists visiting India. We report here the epidemiological, clinical, radiological and laboratory findings of the first cluster of SARS-CoV-2 infection among the tourists. Information was collected on demographic details, travel and exposure history, comorbidities, timelines of events, date of symptom onset and duration of hospitalization from the 16 Italian tourists and an Indian with laboratory-confirmed SARS-CoV-2 infection. The clinical, laboratory, radiologic and treatment data was abstracted from their medical records and all tourists were followed up till their recovery or discharge or death. Throat and deep nasal swab specimens were collected on days 3, 8, 15, 18, 23 and 25 to evaluate viral clearance. A group of 23 Italian tourists reached New Delhi, India, on February 21, 2020 and along with three Indians visited several tourist places in Rajasthan. By March 3, 2020, 17 of the 26 (attack rate: 65.4%) had become positive for SARS-CoV-2 infection. Of these 17 patients, nine were symptomatic, while eight did not show any symptoms. Of the nine who developed symptoms, six were mild, one was severe and two were critically ill. The median duration between the day of confirmation for COVID-19 and RT-PCR negativity was 18 days (range: 12-23 days). Two patients died with a case fatality of 11.8 per cent. This study reconfirms higher rates of transmission among close contacts and therefore, public health measures such as physical distancing, personal hygiene and infection control measures are necessary to prevent transmission.
Sections du résumé
BACKGROUND & OBJECTIVES
OBJECTIVE
A cluster of SARS-CoV-2 infection occurred among Italian tourists visiting India. We report here the epidemiological, clinical, radiological and laboratory findings of the first cluster of SARS-CoV-2 infection among the tourists.
METHODS
METHODS
Information was collected on demographic details, travel and exposure history, comorbidities, timelines of events, date of symptom onset and duration of hospitalization from the 16 Italian tourists and an Indian with laboratory-confirmed SARS-CoV-2 infection. The clinical, laboratory, radiologic and treatment data was abstracted from their medical records and all tourists were followed up till their recovery or discharge or death. Throat and deep nasal swab specimens were collected on days 3, 8, 15, 18, 23 and 25 to evaluate viral clearance.
RESULTS
RESULTS
A group of 23 Italian tourists reached New Delhi, India, on February 21, 2020 and along with three Indians visited several tourist places in Rajasthan. By March 3, 2020, 17 of the 26 (attack rate: 65.4%) had become positive for SARS-CoV-2 infection. Of these 17 patients, nine were symptomatic, while eight did not show any symptoms. Of the nine who developed symptoms, six were mild, one was severe and two were critically ill. The median duration between the day of confirmation for COVID-19 and RT-PCR negativity was 18 days (range: 12-23 days). Two patients died with a case fatality of 11.8 per cent.
INTERPRETATION & CONCLUSIONS
CONCLUSIONS
This study reconfirms higher rates of transmission among close contacts and therefore, public health measures such as physical distancing, personal hygiene and infection control measures are necessary to prevent transmission.
Identifiants
pubmed: 32474558
pii: 284853
doi: 10.4103/ijmr.IJMR_1722_20
pmc: PMC7530458
doi:
Substances chimiques
RNA, Viral
0
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
438-443Déclaration de conflit d'intérêts
None
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