Children's heart and COVID-19: Up-to-date evidence in the form of a systematic review.
COVID-19
Cardiovascular
Coronavirus
Heart
Myocarditis
Severe respiratory distress syndrome
Journal
European journal of pediatrics
ISSN: 1432-1076
Titre abrégé: Eur J Pediatr
Pays: Germany
ID NLM: 7603873
Informations de publication
Date de publication:
Jul 2020
Jul 2020
Historique:
received:
25
04
2020
accepted:
20
05
2020
revised:
17
05
2020
pubmed:
1
6
2020
medline:
7
7
2020
entrez:
1
6
2020
Statut:
ppublish
Résumé
The new coronavirus disease outbreak in 2019 (COVID-19) represents a dramatic challenge for healthcare systems worldwide. As to viral tropism, lungs are not the only COVID-19 target but also the heart may be involved in a not negligible percentage of the infected patients. Myocarditis-related cardiac dysfunction and potentially life-threatening arrhythmias are the main aftermaths. A few studies showed that myocardial injury in adult patients is often linked with a fatal outcome. Conversely, scientific evidence in children is sparse, although several reports were published with the description of a cardiac involvement in COVID-19 paediatric patients. In these young subjects, a background of surgically treated congenital heart disease seems to be a predisposing factor.Conclusion: This systematic review is aimed at summarizing all COVID-19 cases with a cardiac involvement published in paediatric age and trying to explain the underlying mechanisms responsible for COVID-19-related myocardial damage.What is Known:• Coronaviruses proved to be able to jump from animals to humans.• The outbreak of COVID-19 started from China (Dec 2019) and became pandemic.What is New:• Even in childhood, COVID-19 is not without the risk of cardiac involvement.• Myocarditis, heart failure, and arrhythmias are among the possible manifestations.
Identifiants
pubmed: 32474800
doi: 10.1007/s00431-020-03699-0
pii: 10.1007/s00431-020-03699-0
pmc: PMC7261213
doi:
Types de publication
Journal Article
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1079-1087Références
Lancet. 2020 Feb 22;395(10224):565-574
pubmed: 32007145
Prog Cardiovasc Dis. 2020 May - Jun;63(3):390-391
pubmed: 32169400
N Engl J Med. 2020 Feb 20;382(8):727-733
pubmed: 31978945
Clin Res Cardiol. 2020 May;109(5):531-538
pubmed: 32161990
Eur Heart J Cardiovasc Imaging. 2020 Jun 1;21(6):592-598
pubmed: 32242891
Pediatrics. 2020 Jun;145(6):
pubmed: 32179660
Herz. 2020 May;45(3):230-232
pubmed: 32140732
Emerg Microbes Infect. 2020 Dec;9(1):707-713
pubmed: 32208917
Pediatr Pulmonol. 2020 May;55(5):1169-1174
pubmed: 32134205
J Infect Dis. 1992 Jan;165(1):134-40
pubmed: 1309370
Heart Rhythm. 2020 Sep;17(9):e233-e241
pubmed: 32247013
J Infect Dis. 2020 May 11;221(11):1775-1781
pubmed: 32179908
Am J Obstet Gynecol MFM. 2020 May;2(2):100107
pubmed: 32292902
Lancet Respir Med. 2020 Apr;8(4):e21
pubmed: 32171062
Cell. 2020 Apr 16;181(2):271-280.e8
pubmed: 32142651
Zhonghua Xin Xue Guan Bing Za Zhi. 2020 Jul 24;48(7):567-571
pubmed: 32141280
Curr Med Sci. 2020 Apr;40(2):275-280
pubmed: 32207032
JAMA. 2020 Mar 17;323(11):1061-1069
pubmed: 32031570
Clin Chem Lab Med. 2020 Jun 25;58(7):1131-1134
pubmed: 32119647
Lancet. 2020 Mar 28;395(10229):1054-1062
pubmed: 32171076
J Matern Fetal Neonatal Med. 2021 Nov;34(22):3820-3826
pubmed: 31744358
World J Pediatr. 2020 Jun;16(3):251-259
pubmed: 32193831
Eur J Pediatr. 2020 Apr;179(4):683-687
pubmed: 31773329
Eur J Pediatr. 2020 Jan;179(1):171-175
pubmed: 31701239
J Virol. 2020 Mar 17;94(7):
pubmed: 31996437
Hypertension. 2020 Jun;75(6):1382-1385
pubmed: 32208987
Circ Res. 2000 Sep 1;87(5):E1-9
pubmed: 10969042
J Cardiol Cases. 2013 Oct 29;8(6):173-175
pubmed: 30534284
Zhonghua Er Ke Za Zhi. 2020 Feb 02;58(0):E001
pubmed: 32023678
J Med Virol. 2020 Jun;92(6):564-567
pubmed: 32115733
Minerva Cardioangiol. 2020 Apr;68(2):61-64
pubmed: 32150358
Diabetes Metab Syndr. 2020 May - Jun;14(3):247-250
pubmed: 32247212
Pediatr Infect Dis J. 2020 May;39(5):355-368
pubmed: 32310621
Pediatr Res. 2020 Sep;88(3):340-341
pubmed: 32244248
Science. 2005 Sep 16;309(5742):1864-8
pubmed: 16166518
Lancet. 2020 Feb 15;395(10223):497-506
pubmed: 31986264
JAMA Pediatr. 2020 Jul 1;174(7):722-725
pubmed: 32215598
JAMA Cardiol. 2020 Jul 1;5(7):745-747
pubmed: 32242890
JAMA Cardiol. 2020 Jul 1;5(7):831-840
pubmed: 32219363
Pediatr Pulmonol. 2020 May;55(5):E1-E4
pubmed: 32187887
Lancet. 2020 Feb 15;395(10223):507-513
pubmed: 32007143
Nat Rev Cardiol. 2020 May;17(5):259-260
pubmed: 32139904
Acta Paediatr. 2020 Jun;109(6):1082-1083
pubmed: 32212348