Research and Reporting Considerations for Observational Studies Using Electronic Health Record Data.
Journal
Annals of internal medicine
ISSN: 1539-3704
Titre abrégé: Ann Intern Med
Pays: United States
ID NLM: 0372351
Informations de publication
Date de publication:
02 06 2020
02 06 2020
Historique:
entrez:
2
6
2020
pubmed:
2
6
2020
medline:
1
12
2020
Statut:
ppublish
Résumé
Electronic health records (EHRs) are an increasingly important source of real-world health care data for observational research. Analyses of data collected for purposes other than research require careful consideration of data quality as well as the general research and reporting principles relevant to observational studies. The core principles for observational research in general also apply to observational research using EHR data, and these are well addressed in prior literature and guidelines. This article provides additional recommendations for EHR-based research. Considerations unique to EHR-based studies include assessment of the accuracy of computer-executable cohort definitions that can incorporate unstructured data from clinical notes and management of data challenges, such as irregular sampling, missingness, and variation across time and place. Principled application of existing research and reporting guidelines alongside these additional considerations will improve the quality of EHR-based observational studies.
Identifiants
pubmed: 32479175
doi: 10.7326/M19-0873
pmc: PMC7413106
mid: NIHMS1608040
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
S79-S84Subventions
Organisme : NIEHS NIH HHS
ID : K01 ES026837
Pays : United States
Organisme : NLM NIH HHS
ID : R01 LM011369
Pays : United States
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