Bioengineering horizon scan 2020.
bioengineering
biotechnology
foresight
genetics
genomics
horizon scanning
human biology
medicine
none
point of view
Journal
eLife
ISSN: 2050-084X
Titre abrégé: Elife
Pays: England
ID NLM: 101579614
Informations de publication
Date de publication:
29 05 2020
29 05 2020
Historique:
received:
16
12
2019
accepted:
14
05
2020
entrez:
2
6
2020
pubmed:
2
6
2020
medline:
24
2
2021
Statut:
epublish
Résumé
Horizon scanning is intended to identify the opportunities and threats associated with technological, regulatory and social change. In 2017 some of the present authors conducted a horizon scan for bioengineering (Wintle et al., 2017). Here we report the results of a new horizon scan that is based on inputs from a larger and more international group of 38 participants. The final list of 20 issues includes topics spanning from the political (the regulation of genomic data, increased philanthropic funding and malicious uses of neurochemicals) to the environmental (crops for changing climates and agricultural gene drives). The early identification of such issues is relevant to researchers, policy-makers and the wider public.
Identifiants
pubmed: 32479263
doi: 10.7554/eLife.54489
pii: 54489
pmc: PMC7259952
doi:
pii:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : European Research Council
ID : ERC 616510
Pays : International
Organisme : Engineering and Physical Sciences Research Council
ID : EP/S01778X/1
Pays : International
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/P010490/1
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/S020853/1
Pays : United Kingdom
Organisme : Templeton World Charity Foundation
ID : TWCF0128
Pays : International
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/R021554/1
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/M017702/1
Pays : United Kingdom
Informations de copyright
© 2020, Kemp et al.
Déclaration de conflit d'intérêts
LK, LA, CB, RB, RC, MD, AD, RH, LH, AM, CN, SÓ, NP, WP, VR, CR, CR, AR, PS, CS, LS, ET, GU, BW, NZ, WS No competing interests declared, NE Has received funding in the past five years from the following organizations to conduct research and speak on issues related to this article: Greenwall Foundation; Max Planck Institute for Evolutionary Biology; Davis Foundation; National Science Foundation. Has participated in the International Genetically Engineered Machine (iGem) competition as a judge and a member of the Safety Committee several times over the past five years. KH Has participated in the International Genetically Engineered Machine (iGem) competition as a judge and a member of the Safety Committee several times over the past five years; has accepted travel funding from the Max Planck Institute for Evolutionary Biology. TK Holds a grant from the Open Philanthropy Foundation to study DIYbio, including gene drives; member of the IUCN task force on synthetic biology and gene drives; co-chair of the human practices committee of iGEM; member of the biosafety/security advisory board for MIT Broad Foundry; has been affiliated with the Genetic Biocontrol of Invasive Rodents consortium at NC State but has never received any salary or other compensation. PM Co-founder of Biosecure Ltd. JN Listed as an inventor on multiple patents; most relevant patent is US 2019/0323022 A1 and family. Acted as a consultant to BASF (2014-2019). AO Director of the Industrial Biotechnology Alliance, Norwich Research Park; trustee with the New Phytologist Trust. MP Recipient of a grant and a gift from the Open Philanthropy Foundation to study biosecurity at Stanford university; volunteer director of the human practices committee of the international Genetically Engineered Machine (iGEM) Foundation; member of the board of directors of Revive & Restore. EP Holds shares in Celixir Ltd and Arkurity Ltd; has received payment from Deep Science Ventures Ltd, the Nuclear Threat Initiative, Revive & Restore, Celixir Ltd, Arkurity Ltd, CSIRO, International Union for the Conservation of Nature and Biosecure. DS, RS Involved in a consultancy for the ERA-CoBioTech programme (an ERA-Net network funded by Horizon 2020).
Références
Microbiol Mol Biol Rev. 2016 Jun 01;80(3):523-43
pubmed: 27250768
Science. 2017 Sep 22;357(6357):1303-1307
pubmed: 28798043
Elife. 2020 May 29;9:
pubmed: 32479263
Trends Biotechnol. 2018 Aug;36(8):744-747
pubmed: 29550160
Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):8252-8259
pubmed: 30082409
Science. 2019 Jan 4;363(6422):
pubmed: 30606819
Nature. 2019 Nov;575(7784):592-595
pubmed: 31776487
Br J Clin Pharmacol. 2017 Jan;83(1):71-81
pubmed: 27037892
Front Plant Sci. 2019 Jul 09;10:880
pubmed: 31354759
Science. 2015 Dec 18;350(6267):1471-3
pubmed: 26680180
J Law Biosci. 2015 Jul 14;2(3):754-767
pubmed: 27774228
Sci Rep. 2015 Jun 25;5:11183
pubmed: 26108150
Sustain Prod Consum. 2019 Oct;20:58-73
pubmed: 32051840
Cell Syst. 2019 Apr 24;8(4):292-301.e3
pubmed: 31005579
AAS Open Res. 2018 Apr 18;1:13
pubmed: 30714023
J Infect Dis. 2000 Jul;182(1):302-5
pubmed: 10882612
Pest Manag Sci. 2018 Dec;74(12):2671-2679
pubmed: 29999229
Plant Cell Environ. 2018 May;41(5):877-884
pubmed: 29663504
Trends Ecol Evol. 2017 Jun;32(6):464-474
pubmed: 28395941
Sci Rep. 2019 Sep 10;9(1):13047
pubmed: 31506595
Science. 2016 Nov 18;354(6314):900-904
pubmed: 27856910
Clin Pharmacol Ther. 2010 May;87(5):534-6
pubmed: 20407458
Risk Anal. 2018 Sep;38(9):1781-1794
pubmed: 29665625
Am J Hematol. 2019 May;94(S1):S3-S9
pubmed: 30680780
Plant Cell Environ. 2018 May;41(5):1201-1232
pubmed: 28386947
Cell. 2019 Nov 27;179(6):1255-1263.e12
pubmed: 31778652
Soc Stud Sci. 2014 Apr;44(2):218-42
pubmed: 24941612
Front Hum Neurosci. 2017 May 10;11:224
pubmed: 28539877
Trends Biotechnol. 2018 May;36(5):499-510
pubmed: 29455935
Nat Mater. 2019 May;18(5):510-517
pubmed: 30804509
Plant Sci. 2018 Aug;273:110-119
pubmed: 29907303
Science. 2015 Aug 21;349(6250):792-3
pubmed: 26293941
Beilstein J Org Chem. 2019 Feb 26;15:551-557
pubmed: 30873239
Biotechnol J. 2017 Mar;12(3):
pubmed: 28133942
Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):E6736-43
pubmed: 26598698
Nat Biotechnol. 2018 Jul;36(6):547-551
pubmed: 29734293
Nature. 2019 Feb;566(7745):440-442
pubmed: 30809070
Politics Life Sci. 2018 Fall;37(2):180-202
pubmed: 30488813
Trends Ecol Evol. 2017 Jan;32(1):31-40
pubmed: 27955953
Trends Ecol Evol. 2009 Oct;24(10):523-7
pubmed: 19660827
Elife. 2019 Sep 19;8:
pubmed: 31535976
Nat Commun. 2014 Feb 25;5:3353
pubmed: 24569486
Nat Methods. 2019 Aug;16(8):687-694
pubmed: 31308553
Sci Am. 2010 Jun;302(6):84-9
pubmed: 20521485
PLoS One. 2018 Jun 22;13(6):e0198468
pubmed: 29933407
Elife. 2017 Nov 14;6:
pubmed: 29132504
Nat Methods. 2019 Feb;16(2):167-170
pubmed: 30643213
Proc Natl Acad Sci U S A. 2018 Dec 4;115(49):E11455-E11464
pubmed: 30459276
BMC Proc. 2018 Jul 19;12(Suppl 8):9
pubmed: 30079101
Cell. 2020 Feb 20;180(4):688-702.e13
pubmed: 32084340
Gut Microbes. 2013 Jul-Aug;4(4):271-80
pubmed: 23651955
Nat Biotechnol. 2019 Jun;37(6):692
pubmed: 31114034
Nanoscale. 2018 Jan 25;10(4):1667-1679
pubmed: 29231944
Psychiatry Res. 2015 Sep 30;229(1-2):12-20
pubmed: 26187342
Nature. 2014 Aug 7;512(7512):23-5
pubmed: 25100467
Arch Intern Med. 2010 Apr 26;170(8):675-82
pubmed: 20421551
Trends Biotechnol. 2018 Dec;36(12):1211-1218
pubmed: 30220578
Science. 2019 Sep 20;365(6459):1291-1295
pubmed: 31604238
Front Public Health. 2019 Mar 07;7:42
pubmed: 30899755
Front Bioeng Biotechnol. 2019 Feb 11;7:18
pubmed: 30805337