Rainer Breitling

Affiliations

Manchester Institute of Biotechnology, Faculty of Science and Bioengineering, University of Manchester, Manchester, United Kingdom.

Publications (35)

Bioengineering horizon scan 2020.

eLife

Avec: Luke Kemp , Laura Adam , Christian R Boehm , Rainer Breitling , Rocco Casagrande , Malcolm Dando , Appolinaire Djikeng , Nicholas G Evans , Richard Hammond , Kelly Hills , Lauren A Holt , Todd Kuiken , Alemka Markotić , Piers Millett , Johnathan A Napier , Cassidy Nelson , Seán S ÓhÉigeartaigh , Anne Osbourn , Megan Palmer , Nicola J Patron , Edward Perello , Wibool Piyawattanametha , Vanessa Restrepo-Schild , Clarissa Rios-Rojas , Catherine Rhodes , Anna Roessing , Deborah Scott , Philip Shapira , Christopher Simuntala , Robert Dj Smith , Lalitha S Sundaram , Eriko Takano , Gwyn Uttmark , Bonnie Wintle , Nadia B Zahra , William J Sutherland

Synthetic biology for fibres, adhesives and active camouflage materials in protection and aerospace.

MRS communications

Avec: Aled D Roberts , William Finnigan , Emmanuel Wolde-Michael , Paul Kelly , Jonny J Blaker , Sam Hay , Rainer Breitling , Eriko Takano , Nigel S Scrutton

SelProm: A Queryable and Predictive Expression Vector Selection Tool for

ACS synthetic biology

Avec: Adrian J Jervis , Pablo Carbonell , Sandra Taylor , Rehana Sung , Mark S Dunstan , Christopher J Robinson , Rainer Breitling , Eriko Takano , Nigel S Scrutton

Transduction and transfection of difficult-to-transfect cells: Systematic attempts for the transfection of protozoa Leishmania.

Journal of cellular biochemistry

Avec: Andrea-Anneliese Keller , Berith Scheiding , Reinhard Breitling , Andreas Licht , Peter Hemmerich , Stefan Lorkowski , Siegmund Reissmann

Highly multiplexed, fast and accurate nanopore sequencing for verification of synthetic DNA constructs and sequence libraries.

Synthetic biology (Oxford, England)

Avec: Andrew Currin , Neil Swainston , Mark S Dunstan , Adrian J Jervis , Paul Mulherin , Christopher J Robinson , Sandra Taylor , Pablo Carbonell , Katherine A Hollywood , Cunyu Yan , Eriko Takano , Nigel S Scrutton , Rainer Breitling

Data integration and mechanistic modelling for breast cancer biology: Current state and future directions.

Current opinion in endocrine and metabolic research

Avec: Hanyi Mo , Rainer Breitling , Chiara Francavilla , Jean-Marc Schwartz

Non-covalent protein-based adhesives for transparent substrates-bovine serum albumin vs. recombinant spider silk.

Materials today. Bio

Avec: A D Roberts , W Finnigan , P P Kelly , M Faulkner , R Breitling , E Takano , N S Scrutton , J J Blaker , S Hay

Blood, sweat, and tears: extraterrestrial regolith biocomposites with

Materials today. Bio

Avec: A D Roberts , D R Whittall , R Breitling , E Takano , J J Blaker , S Hay , N S Scrutton

Carboxylic acid reductase-dependent biosynthesis of eugenol and related allylphenols.

Microbial cell factories

Avec: Erik K R Hanko , Kris Niño G Valdehuesa , Koen J A Verhagen , Jakub Chromy , Ruth A Stoney , Jeremy Chua , Cunyu Yan , Johannes A Roubos , Joep Schmitz , Rainer Breitling

ipaPy2: Integrated Probabilistic Annotation (IPA) 2.0-an improved Bayesian-based method for the annotation of LC-MS/MS untargeted metabolomics data.

Bioinformatics (Oxford, England)

Avec: Francesco Del Carratore , William Eagles , Juraj Borka , Rainer Breitling

Bioproduction of methylated phenylpropenes and isoeugenol in

Metabolic engineering communications

Avec: Jeremy Chua , Erik K R Hanko , Andrew Yiakoumetti , Ruth A Stoney , Jakub Chromy , Kris Niño G Valdehuesa , Katherine A Hollywood , Cunyu Yan , Eriko Takano , Rainer Breitling

Rapid prototyping of microbial production strains for the biomanufacture of potential materials monomers.

Metabolic engineering

Avec: Christopher J Robinson , Pablo Carbonell , Adrian J Jervis , Cunyu Yan , Katherine A Hollywood , Mark S Dunstan , Andrew Currin , Neil Swainston , Reynard Spiess , Sandra Taylor , Paul Mulherin , Steven Parker , William Rowe , Nicholas E Matthews , Kirk J Malone , Rosalind Le Feuvre , Philip Shapira , Perdita Barran , Nicholas J Turner , Jason Micklefield , Rainer Breitling , Eriko Takano , Nigel S Scrutton

Exploring novel bacterial terpene synthases.

PloS one

Avec: Gajendar Komati Reddy , Nicole G H Leferink , Maiko Umemura , Syed T Ahmed , Rainer Breitling , Nigel S Scrutton , Eriko Takano

Integrated Probabilistic Annotation: A Bayesian-Based Annotation Method for Metabolomic Profiles Integrating Biochemical Connections, Isotope Patterns, and Adduct Relationships.

Analytical chemistry

Avec: Francesco Del Carratore , Kamila Schmidt , Maria Vinaixa , Katherine A Hollywood , Caitlin Greenland-Bews , Eriko Takano , Simon Rogers , Rainer Breitling

Investigation of the effects of actinorhodin biosynthetic gene cluster expression and a rpoB point mutation on the metabolome of Streptomyces coelicolor M1146.

Journal of bioscience and bioengineering

Avec: Katsuaki Nitta , Rainer Breitling , Eriko Takano , Sastia P Putri , Eiichiro Fukusaki

Synthetic biology approaches to actinomycete strain improvement.

FEMS microbiology letters

Avec: Rainer Breitling , Martina Avbelj , Oksana Bilyk , Francesco Del Carratore , Alessandro Filisetti , Erik K R Hanko , Marianna Iorio , Rosario Pérez Redondo , Fernando Reyes , Michelle Rudden , Emmanuele Severi , Lucija Slemc , Kamila Schmidt , Dominic R Whittall , Stefano Donadio , Antonio Rodríguez García , Olga Genilloud , Gregor Kosec , Davide De Lucrezia , Hrvoje Petković , Gavin Thomas , Eriko Takano

The evolving art of creating genetic diversity: From directed evolution to synthetic biology.

Biotechnology advances

Avec: Andrew Currin , Steven Parker , Christopher J Robinson , Eriko Takano , Nigel S Scrutton , Rainer Breitling

Microbial production of the plant flavanone hesperetin from caffeic acid.

BMC research notes

Avec: Erik K R Hanko , João Correia , Caio S Souza , Alison Green , Jakub Chromy , Ruth Stoney , Cunyu Yan , Eriko Takano , Diana Lousa , Cláudio M Soares , Rainer Breitling

An adaptable

Molecular omics

Avec: Megan Uttley , Grace Horne , Areti Tsigkinopoulou , Francesco Del Carratore , Aliah Hawari , Magdalena Kiezel-Tsugunova , Alexandra C Kendall , Janette Jones , David Messenger , Ranjit Kaur Bhogal , Rainer Breitling , Anna Nicolaou

Computational identification of co-evolving multi-gene modules in microbial biosynthetic gene clusters.

Communications biology

Avec: Francesco Del Carratore , Konrad Zych , Matthew Cummings , Eriko Takano , Marnix H Medema , Rainer Breitling

Machine Learning of Designed Translational Control Allows Predictive Pathway Optimization in Escherichia coli.

ACS synthetic biology

Avec: Adrian J Jervis , Pablo Carbonell , Maria Vinaixa , Mark S Dunstan , Katherine A Hollywood , Christopher J Robinson , Nicholas J W Rattray , Cunyu Yan , Neil Swainston , Andrew Currin , Rehana Sung , Helen Toogood , Sandra Taylor , Jean-Loup Faulon , Rainer Breitling , Eriko Takano , Nigel S Scrutton

Unravelling the γ-butyrolactone network in Streptomyces coelicolor by computational ensemble modelling.

PLoS computational biology

Avec: Areti Tsigkinopoulou , Eriko Takano , Rainer Breitling

The effect of terminal globular domains on the response of recombinant mini-spidroins to fiber spinning triggers.

Scientific reports

Avec: William Finnigan , Aled D Roberts , Cosimo Ligorio , Nigel S Scrutton , Rainer Breitling , Jonny J Blaker , Eriko Takano

Harnessing intercellular signals to engineer the soil microbiome.

Natural product reports

Avec: Jack A Connolly , William R Harcombe , Michael J Smanski , Linda L Kinkel , Eriko Takano , Rainer Breitling

Host Systems for the Production of Recombinant Spider Silk.

Trends in biotechnology

Avec: Dominic R Whittall , Katherine V Baker , Rainer Breitling , Eriko Takano

Multi-Omics Analysis of the Effect of cAMP on Actinorhodin Production in

Frontiers in bioengineering and biotechnology

Avec: Katsuaki Nitta , Francesco Del Carratore , Rainer Breitling , Eriko Takano , Sastia P Putri , Eiichiro Fukusaki

Engineering

Synthetic biology (Oxford, England)

Avec: Mark S Dunstan , Christopher J Robinson , Adrian J Jervis , Cunyu Yan , Pablo Carbonell , Katherine A Hollywood , Andrew Currin , Neil Swainston , Rosalind Le Feuvre , Jason Micklefield , Jean-Loup Faulon , Rainer Breitling , Nicholas Turner , Eriko Takano , Nigel S Scrutton

Dynamics of the human skin mediator lipidome in response to dietary ω-3 fatty acid supplementation.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Avec: Alexandra C Kendall , Suzanne M Pilkington , Sharon A Murphy , Francesco Del Carratore , Anggit L Sunarwidhi , Magdalena Kiezel-Tsugunova , Paula Urquhart , Rachel E B Watson , Rainer Breitling , Lesley E Rhodes , Anna Nicolaou

Multi-omics Study of Planobispora rosea, Producer of the Thiopeptide Antibiotic GE2270A.

mSystems

Avec: Francesco Del Carratore , Marianna Iorio , Mercedes Pérez-Bonilla , Kamila Schmidt , Rosario Pérez-Redondo , Margherita Sosio , Sandy J Macdonald , Ivan S Gyulev , Areti Tsigkinopoulou , Gavin H Thomas , Olga Genilloud , Antonio Rodríguez-García , Stefano Donadio , Rainer Breitling , Eriko Takano

Expanding flavone and flavonol production capabilities in

Frontiers in bioengineering and biotechnology

Avec: Andrew Yiakoumetti , Erik K R Hanko , Yutong Zou , Jeremy Chua , Jakub Chromy , Ruth A Stoney , Kris Niño G Valdehuesa , Jack A Connolly , Cunyu Yan , Katherine A Hollywood , Eriko Takano , Rainer Breitling

Synthetic Biology of Natural Products Engineering: Recent Advances Across the Discover-Design-Build-Test-Learn Cycle.

ACS synthetic biology

Avec: Jonathan Foldi , Jack A Connolly , Eriko Takano , Rainer Breitling

Biotechnological application of Streptomyces for the production of clinical drugs and other bioactive molecules.

Current opinion in biotechnology

Avec: Francesco Del Carratore , Erik Kr Hanko , Rainer Breitling , Eriko Takano

TFBMiner: A User-Friendly Command Line Tool for the Rapid Mining of Transcription Factor-Based Biosensors.

ACS synthetic biology

Avec: Erik K R Hanko , Tariq A Joosab Noor Mahomed , Ruth A Stoney , Rainer Breitling

Towards engineering and production of artificial spider silk using tools of synthetic biology.

Engineering biology

Avec: Hashwardhan Poddar , Rainer Breitling , Eriko Takano

SelenzymeRF: updated enzyme suggestion software for unbalanced biochemical reactions.

Computational and structural biotechnology journal

Avec: Ruth A Stoney , Erik K R Hanko , Pablo Carbonell , Rainer Breitling

Réseau de co-auteurs

Eriko Takano 25 collaborations

Nigel S Scrutton 9 collaborations

Francesco Del Carratore 9 collaborations

Cunyu Yan 8 collaborations

Katherine A Hollywood 7 collaborations

Erik K R Hanko 7 collaborations

Pablo Carbonell 6 collaborations

Christopher J Robinson 6 collaborations

Adrian J Jervis 5 collaborations

Mark S Dunstan 5 collaborations

Andrew Currin 5 collaborations

Ruth A Stoney 5 collaborations

Sandra Taylor 4 collaborations

Neil Swainston 4 collaborations

Jakub Chromy 4 collaborations

Kris Niño G Valdehuesa 3 collaborations

Jeremy Chua 3 collaborations

Kamila Schmidt 3 collaborations

Areti Tsigkinopoulou 3 collaborations

Jack A Connolly 3 collaborations

Philip Shapira 2 collaborations

Aled D Roberts 2 collaborations

William Finnigan 2 collaborations

Jonny J Blaker 2 collaborations

Rehana Sung 2 collaborations

Paul Mulherin 2 collaborations

A D Roberts 2 collaborations

R Breitling 2 collaborations

E Takano 2 collaborations

N S Scrutton 2 collaborations

J J Blaker 2 collaborations

S Hay 2 collaborations

Andrew Yiakoumetti 2 collaborations

Steven Parker 2 collaborations

Rosalind Le Feuvre 2 collaborations

Jason Micklefield 2 collaborations

Maria Vinaixa 2 collaborations

Katsuaki Nitta 2 collaborations

Sastia P Putri 2 collaborations

Eiichiro Fukusaki 2 collaborations

Marianna Iorio 2 collaborations

Dominic R Whittall 2 collaborations

Stefano Donadio 2 collaborations

Olga Genilloud 2 collaborations

Magdalena Kiezel-Tsugunova 2 collaborations

Alexandra C Kendall 2 collaborations

Anna Nicolaou 2 collaborations

Jean-Loup Faulon 2 collaborations

Luke Kemp 1 collaboration

Laura Adam 1 collaboration

Christian R Boehm 1 collaboration

Rocco Casagrande 1 collaboration

Malcolm Dando 1 collaboration

Appolinaire Djikeng 1 collaboration

Nicholas G Evans 1 collaboration

Richard Hammond 1 collaboration

Kelly Hills 1 collaboration

Lauren A Holt 1 collaboration

Todd Kuiken 1 collaboration

Alemka Markotić 1 collaboration

Piers Millett 1 collaboration

Johnathan A Napier 1 collaboration

Cassidy Nelson 1 collaboration

Seán S ÓhÉigeartaigh 1 collaboration

Anne Osbourn 1 collaboration

Megan Palmer 1 collaboration

Nicola J Patron 1 collaboration

Edward Perello 1 collaboration

Wibool Piyawattanametha 1 collaboration

Vanessa Restrepo-Schild 1 collaboration

Clarissa Rios-Rojas 1 collaboration

Catherine Rhodes 1 collaboration

Anna Roessing 1 collaboration

Deborah Scott 1 collaboration

Christopher Simuntala 1 collaboration

Robert Dj Smith 1 collaboration

Lalitha S Sundaram 1 collaboration

Gwyn Uttmark 1 collaboration

Bonnie Wintle 1 collaboration

Nadia B Zahra 1 collaboration

William J Sutherland 1 collaboration

Emmanuel Wolde-Michael 1 collaboration

Paul Kelly 1 collaboration

Sam Hay 1 collaboration

Andrea-Anneliese Keller 1 collaboration

Berith Scheiding 1 collaboration

Reinhard Breitling 1 collaboration

Andreas Licht 1 collaboration

Peter Hemmerich 1 collaboration

Stefan Lorkowski 1 collaboration

Siegmund Reissmann 1 collaboration

Hanyi Mo 1 collaboration

Chiara Francavilla 1 collaboration

Jean-Marc Schwartz 1 collaboration

W Finnigan 1 collaboration

P P Kelly 1 collaboration

M Faulkner 1 collaboration

D R Whittall 1 collaboration

Koen J A Verhagen 1 collaboration

Johannes A Roubos 1 collaboration

Joep Schmitz 1 collaboration

William Eagles 1 collaboration

Juraj Borka 1 collaboration

Reynard Spiess 1 collaboration

William Rowe 1 collaboration

Nicholas E Matthews 1 collaboration

Kirk J Malone 1 collaboration

Perdita Barran 1 collaboration

Nicholas J Turner 1 collaboration

Gajendar Komati Reddy 1 collaboration

Nicole G H Leferink 1 collaboration

Maiko Umemura 1 collaboration

Syed T Ahmed 1 collaboration

Caitlin Greenland-Bews 1 collaboration

Simon Rogers 1 collaboration

Martina Avbelj 1 collaboration

Oksana Bilyk 1 collaboration

Alessandro Filisetti 1 collaboration

Rosario Pérez Redondo 1 collaboration

Fernando Reyes 1 collaboration

Michelle Rudden 1 collaboration

Emmanuele Severi 1 collaboration

Lucija Slemc 1 collaboration

Antonio Rodríguez García 1 collaboration

Gregor Kosec 1 collaboration

Davide De Lucrezia 1 collaboration

Hrvoje Petković 1 collaboration

Gavin Thomas 1 collaboration

João Correia 1 collaboration

Caio S Souza 1 collaboration

Alison Green 1 collaboration

Ruth Stoney 1 collaboration

Diana Lousa 1 collaboration

Cláudio M Soares 1 collaboration

Megan Uttley 1 collaboration

Grace Horne 1 collaboration

Aliah Hawari 1 collaboration

Janette Jones 1 collaboration

David Messenger 1 collaboration

Ranjit Kaur Bhogal 1 collaboration

Konrad Zych 1 collaboration

Matthew Cummings 1 collaboration

Marnix H Medema 1 collaboration

Nicholas J W Rattray 1 collaboration

Helen Toogood 1 collaboration

Cosimo Ligorio 1 collaboration

William R Harcombe 1 collaboration

Michael J Smanski 1 collaboration

Linda L Kinkel 1 collaboration

Katherine V Baker 1 collaboration

Nicholas Turner 1 collaboration

Suzanne M Pilkington 1 collaboration

Sharon A Murphy 1 collaboration

Anggit L Sunarwidhi 1 collaboration

Paula Urquhart 1 collaboration

Rachel E B Watson 1 collaboration

Lesley E Rhodes 1 collaboration

Mercedes Pérez-Bonilla 1 collaboration

Rosario Pérez-Redondo 1 collaboration

Margherita Sosio 1 collaboration

Sandy J Macdonald 1 collaboration

Ivan S Gyulev 1 collaboration

Gavin H Thomas 1 collaboration

Antonio Rodríguez-García 1 collaboration

Yutong Zou 1 collaboration

Jonathan Foldi 1 collaboration

Erik Kr Hanko 1 collaboration

Tariq A Joosab Noor Mahomed 1 collaboration

Hashwardhan Poddar 1 collaboration