Expanding flavone and flavonol production capabilities in

Escherichia coli biotransformation cytochrome P450 flavones flavonoids flavonols rapid prototyping

Journal

Frontiers in bioengineering and biotechnology
ISSN: 2296-4185
Titre abrégé: Front Bioeng Biotechnol
Pays: Switzerland
ID NLM: 101632513

Informations de publication

Date de publication:
2023
Historique:
received: 10 08 2023
accepted: 04 10 2023
medline: 3 11 2023
pubmed: 3 11 2023
entrez: 3 11 2023
Statut: epublish

Résumé

Flavones and flavonols are important classes of flavonoids with nutraceutical and pharmacological value, and their production by fermentation with recombinant microorganisms promises to be a scalable and economically favorable alternative to extraction from plant sources. Flavones and flavonols have been produced recombinantly in a number of microorganisms, with

Identifiants

pubmed: 37920246
doi: 10.3389/fbioe.2023.1275651
pii: 1275651
pmc: PMC10619664
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1275651

Informations de copyright

Copyright © 2023 Yiakoumetti, Hanko, Zou, Chua, Chromy, Stoney, Valdehuesa, Connolly, Yan, Hollywood, Takano and Breitling.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.

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Auteurs

Andrew Yiakoumetti (A)

Manchester Institute of Biotechnology, School of Chemistry, Faculty of Science and Engineering, University of Manchester, Manchester, United Kingdom.

Erik K R Hanko (EKR)

Manchester Institute of Biotechnology, School of Chemistry, Faculty of Science and Engineering, University of Manchester, Manchester, United Kingdom.

Yutong Zou (Y)

Manchester Institute of Biotechnology, School of Chemistry, Faculty of Science and Engineering, University of Manchester, Manchester, United Kingdom.

Jeremy Chua (J)

Manchester Institute of Biotechnology, School of Chemistry, Faculty of Science and Engineering, University of Manchester, Manchester, United Kingdom.

Jakub Chromy (J)

Manchester Institute of Biotechnology, School of Chemistry, Faculty of Science and Engineering, University of Manchester, Manchester, United Kingdom.

Ruth A Stoney (RA)

Manchester Institute of Biotechnology, School of Chemistry, Faculty of Science and Engineering, University of Manchester, Manchester, United Kingdom.

Kris Niño G Valdehuesa (KNG)

Manchester Institute of Biotechnology, School of Chemistry, Faculty of Science and Engineering, University of Manchester, Manchester, United Kingdom.

Jack A Connolly (JA)

Manchester Institute of Biotechnology, School of Chemistry, Faculty of Science and Engineering, University of Manchester, Manchester, United Kingdom.

Cunyu Yan (C)

Manchester Institute of Biotechnology, School of Chemistry, Faculty of Science and Engineering, University of Manchester, Manchester, United Kingdom.

Katherine A Hollywood (KA)

Manchester Institute of Biotechnology, School of Chemistry, Faculty of Science and Engineering, University of Manchester, Manchester, United Kingdom.

Eriko Takano (E)

Manchester Institute of Biotechnology, School of Chemistry, Faculty of Science and Engineering, University of Manchester, Manchester, United Kingdom.

Rainer Breitling (R)

Manchester Institute of Biotechnology, School of Chemistry, Faculty of Science and Engineering, University of Manchester, Manchester, United Kingdom.

Classifications MeSH