Measurement of faecal haemoglobin with a faecal immunochemical test can assist in defining which patients attending primary care with rectal bleeding require urgent referral.

Adenoma colorectal cancer colorectal disease faecal haemoglobin faecal immunochemical test inflammatory bowel disease primary care rectal bleeding

Journal

Annals of clinical biochemistry
ISSN: 1758-1001
Titre abrégé: Ann Clin Biochem
Pays: England
ID NLM: 0324055

Informations de publication

Date de publication:
07 2020
Historique:
pubmed: 3 6 2020
medline: 23 1 2021
entrez: 3 6 2020
Statut: ppublish

Résumé

Current guidelines document persistent rectal bleeding as an alarm symptom in patients presenting to primary care. We studied whether a faecal immunochemical test could assist in their assessment. From December 2015, faecal immunochemical tests were routinely available to primary care when assessing patients with new-onset bowel symptoms: general practitioners were encouraged to include faecal haemoglobin concentration (f-Hb) within any referral to secondary care. Results with f-Hb ≥10  Of 1447 patients with a faecal immunochemical test result and colonoscopy outcome, SBD was diagnosed in 296 patients (20.5%; 95 with CRC, 133 with HRA, and 68 with IBD). Four hundred and sixty-two patients (31.9%) reported rectal bleeding: 294 had f-Hb ≥10  Patients with rectal bleeding and f-Hb <10 

Sections du résumé

BACKGROUND
Current guidelines document persistent rectal bleeding as an alarm symptom in patients presenting to primary care. We studied whether a faecal immunochemical test could assist in their assessment.
METHODS
From December 2015, faecal immunochemical tests were routinely available to primary care when assessing patients with new-onset bowel symptoms: general practitioners were encouraged to include faecal haemoglobin concentration (f-Hb) within any referral to secondary care. Results with f-Hb ≥10 
RESULTS
Of 1447 patients with a faecal immunochemical test result and colonoscopy outcome, SBD was diagnosed in 296 patients (20.5%; 95 with CRC, 133 with HRA, and 68 with IBD). Four hundred and sixty-two patients (31.9%) reported rectal bleeding: 294 had f-Hb ≥10 
CONCLUSION
Patients with rectal bleeding and f-Hb <10 

Identifiants

pubmed: 32482080
doi: 10.1177/0004563220935622
doi:

Substances chimiques

Hemoglobins 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

325-327

Auteurs

Jayne Digby (J)

Centre for Research into Cancer Prevention and Screening, University of Dundee, Ninewells Hospital and Medical School, Dundee, Scotland, UK.

Judith A Strachan (JA)

Department of Blood Sciences, Ninewells Hospital and Medical School, Dundee, Scotland, UK.

Rebecca McCann (R)

Department of Blood Sciences, Ninewells Hospital and Medical School, Dundee, Scotland, UK.

Robert Jc Steele (RJ)

Centre for Research into Cancer Prevention and Screening, University of Dundee, Ninewells Hospital and Medical School, Dundee, Scotland, UK.

Callum G Fraser (CG)

Centre for Research into Cancer Prevention and Screening, University of Dundee, Ninewells Hospital and Medical School, Dundee, Scotland, UK.

Craig Mowat (C)

Department of Gastroenterology, Ninewells Hospital and Medical School, Dundee, Scotland, UK.

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