Impact of different iterative metal artifact reduction (iMAR) algorithms on PET/CT attenuation correction after port implementation.
Attenuation correction
Iterative metal artifact reduction
PET/CT
Port system
Journal
European journal of radiology
ISSN: 1872-7727
Titre abrégé: Eur J Radiol
Pays: Ireland
ID NLM: 8106411
Informations de publication
Date de publication:
Aug 2020
Aug 2020
Historique:
received:
18
02
2020
revised:
29
04
2020
accepted:
07
05
2020
pubmed:
3
6
2020
medline:
20
1
2021
entrez:
3
6
2020
Statut:
ppublish
Résumé
To evaluate the effect of various interactive metal artifact reduction (iMAR) algorithms on attenuation correction in the vicinity of port chambers in PET/CT. In this prospective study, 30 oncological patients (12 female, 18 male, mean age 59.6 ± 10.5y) with implanted port chambers undergoing 18F-FDG PET/CT were included. CT images were reconstructed with standard weighted filtered back projection (WFBP) and three different iMAR algorithms (hip, dental filling (DF) and pacemaker (PM)). PET attenuation correction was performed with all four CT datasets. SUVmean, SUVmax and HU measurements were performed in fat and muscle tissue in the vicinity of the port chamber at the location of the strongest bright and dark band artifacts. Differences between HU and SUV values across all CT- and PET-images were investigated using a paired t-test. Bonferroni correction was used to prevent alpha-error accumulation (p < 0.008). In comparison to WFBP (fat: 94.2 ± 53.9 HU, muscle: 197.6 ± 49.2 HU) all three iMAR algorithms led to a decrease of HU in bright band artifacts. iMAR-DF led to a decrease of 159.2 % (fat: -51.9 ± 58.5 HU, muscle: 94.5 ± 55.3 HU), iMAR-hip of 138.3 % (fat: -30.3 ± 58.5, muscle: 70.4 ± 28.8) and iMAR-PM of 122.3 % (fat: -21.2 ± 47.2 HU, muscle: 72.5 ± 25.1 HU; for all p < 0.008). There was no significant effect of iMAR on SUV measurements in comparison to WFBP. iMAR leads to a significant change of HU values in artifacts caused by port catheter chambers in comparison to WFBP. However, no significant differences in attenuation correction and consecutive changes in SUV measurements can be observed.
Identifiants
pubmed: 32485336
pii: S0720-048X(20)30254-0
doi: 10.1016/j.ejrad.2020.109065
pii:
doi:
Substances chimiques
Metals
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
109065Informations de copyright
Copyright © 2020 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest All authors declare that there are no potential conflict of interest. Benedikt M. Schaarschmidt is a stockholder for Bayer AG, General Electric, Siemens AG, Siemens Healthineers AG, TEVA Pharmaceuticals.