Hyponatremia in the cancer patient.

Antidiuretic Hormone Receptor Antagonists / therapeutic use Benzazepines Humans Hyponatremia / diagnosis Inappropriate ADH Syndrome / diagnosis Neoplasms / complications Quality of Life Tolvaptan
adrenal insufficiency cancer hyponatremia immunotherapy inappropriate ADH syndrome onconephrology tolvaptan urea

Journal

Kidney international
ISSN: 1523-1755
Titre abrégé: Kidney Int
Pays: United States
ID NLM: 0323470

Informations de publication

Date de publication:
10 2020
Historique:
received: 10 02 2020
revised: 28 04 2020
accepted: 11 05 2020
pubmed: 5 6 2020
medline: 22 6 2021
entrez: 5 6 2020
Statut: ppublish

Résumé

Hyponatremia is a common electrolyte disorder observed in a wide variety of malignancies and is associated with substantial morbidity and mortality. Newer cancer therapies have improved patient outcomes while contributing to new cases of hyponatremia. Patients should be monitored closely for the development of vasopressin- and non-vasopressin-mediated hyponatremia. Acute and symptomatic forms of hyponatremia require urgent intervention, and recent findings support the correction of chronic "asymptomatic" hyponatremia. Optimizing hyponatremia may reduce medical costs, and improve cancer survival likelihood and quality of life. In this article, we review the epidemiology, pathophysiology, etiology, diagnosis, and treatment of hyponatremia in the cancer patient.

Identifiants

DOI: 10.1016/j.kint.2020.05.015 PMID: 32497528
pubmed: 32497528
pii: S0085-2538(20)30559-7
doi: 10.1016/j.kint.2020.05.015
pii:
doi:

Substances chimiques

Antidiuretic Hormone Receptor Antagonists 0
Benzazepines 0
Tolvaptan 21G72T1950

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

870-882

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright © 2020 International Society of Nephrology. Published by Elsevier Inc. All rights reserved.

Auteurs

Biruh T Workeneh (BT)

Section of Nephrology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

Kenar D Jhaveri (KD)

Division of Kidney Diseases and Hypertension, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Great Neck, New York, USA. Electronic address: kjhaveri@northwell.edu.

Helbert Rondon-Berrios (H)

Renal-Electrolyte Division. University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA. Electronic address: rondonberriosh@upmc.edu.

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Antagonistes des récepteurs de l'hormone antidiurétique › Hyponatremia in the cancer patient.
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Benzazépines › Hyponatremia in the cancer patient.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Hyponatremia in the cancer patient.
questionsmedicales.fr › Maladies métaboliques et nutritionnelles › Maladies métaboliques › Troubles de l'équilibre hydroélectrolytique › Hyponatrémie › Hyponatremia in the cancer patient.
questionsmedicales.fr › Maladies endocriniennes › Maladies de l'hypophyse › Syndrome de sécrétion inappropriée d'ADH › Hyponatremia in the cancer patient.
questionsmedicales.fr › Tumeurs › Hyponatremia in the cancer patient.
questionsmedicales.fr › Environnement et santé publique › Santé publique › Mesures épidémiologiques › Démographie › État de santé › Qualité de vie › Hyponatremia in the cancer patient.
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Benzazépines › Tolvaptan › Hyponatremia in the cancer patient.