Implementation of model explainability for a basic brain tumor detection using convolutional neural networks on MRI slices.


Journal

Neuroradiology
ISSN: 1432-1920
Titre abrégé: Neuroradiology
Pays: Germany
ID NLM: 1302751

Informations de publication

Date de publication:
Nov 2020
Historique:
received: 22 04 2020
accepted: 22 05 2020
pubmed: 6 6 2020
medline: 8 7 2021
entrez: 6 6 2020
Statut: ppublish

Résumé

While neural networks gain popularity in medical research, attempts to make the decisions of a model explainable are often only made towards the end of the development process once a high predictive accuracy has been achieved. In order to assess the advantages of implementing features to increase explainability early in the development process, we trained a neural network to differentiate between MRI slices containing either a vestibular schwannoma, a glioblastoma, or no tumor. Making the decisions of a network more explainable helped to identify potential bias and choose appropriate training data. Model explainability should be considered in early stages of training a neural network for medical purposes as it may save time in the long run and will ultimately help physicians integrate the network's predictions into a clinical decision.

Identifiants

pubmed: 32500277
doi: 10.1007/s00234-020-02465-1
pii: 10.1007/s00234-020-02465-1
doi:

Substances chimiques

Contrast Media 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1515-1518

Auteurs

Paul Windisch (P)

European CyberKnife Center, Munich, Germany. paul.windisch@ksw.ch.
Department of Radiation Oncology, Kantonsspital Winterthur, Winterthur, Switzerland. paul.windisch@ksw.ch.

Pascal Weber (P)

European CyberKnife Center, Munich, Germany.

Christoph Fürweger (C)

European CyberKnife Center, Munich, Germany.
Department of Stereotaxy and Functional Neurosurgery, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.

Felix Ehret (F)

European CyberKnife Center, Munich, Germany.

Markus Kufeld (M)

European CyberKnife Center, Munich, Germany.

Daniel Zwahlen (D)

Department of Radiation Oncology, Kantonsspital Winterthur, Winterthur, Switzerland.

Alexander Muacevic (A)

European CyberKnife Center, Munich, Germany.

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Classifications MeSH