Archaeal DNA Replication.


Journal

Annual review of microbiology
ISSN: 1545-3251
Titre abrégé: Annu Rev Microbiol
Pays: United States
ID NLM: 0372370

Informations de publication

Date de publication:
08 09 2020
Historique:
pubmed: 7 6 2020
medline: 23 7 2021
entrez: 7 6 2020
Statut: ppublish

Résumé

It is now well recognized that the information processing machineries of archaea are far more closely related to those of eukaryotes than to those of their prokaryotic cousins, the bacteria. Extensive studies have been performed on the structure and function of the archaeal DNA replication origins, the proteins that define them, and the macromolecular assemblies that drive DNA unwinding and nascent strand synthesis. The results from various archaeal organisms across the archaeal domain of life show surprising levels of diversity at many levels-ranging from cell cycle organization to chromosome ploidy to replication mode and nature of the replicative polymerases. In the following, we describe recent advances in the field, highlighting conserved features and lineage-specific innovations.

Identifiants

pubmed: 32503372
doi: 10.1146/annurev-micro-020518-115443
pmc: PMC7712474
mid: NIHMS1645546
doi:

Substances chimiques

Archaeal Proteins 0
DNA, Archaeal 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

65-80

Subventions

Organisme : NIGMS NIH HHS
ID : R01 GM125579
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM135178
Pays : United States

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Auteurs

Mark D Greci (MD)

Department of Biology, Indiana University, Bloomington, Indiana 47405, USA; email: stedbell@indiana.edu.

Stephen D Bell (SD)

Department of Biology, Indiana University, Bloomington, Indiana 47405, USA; email: stedbell@indiana.edu.
Department of Molecular and Cellular Biochemistry, Indiana University, Bloomington, Indiana 47405, USA.

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Classifications MeSH