The impact of cardiovascular risk factors on global longitudinal strain over a decade in the general population: the copenhagen city heart study.
Adaptation, Physiological
Adult
Aged
Cardiovascular Diseases
/ diagnostic imaging
Denmark
/ epidemiology
Echocardiography, Doppler
Female
Humans
Longitudinal Studies
Male
Middle Aged
Predictive Value of Tests
Prognosis
Prospective Studies
Risk Assessment
Risk Factors
Time Factors
Ventricular Function, Left
Ventricular Remodeling
Echocardiography
General population
Global longitudinal strain
Risk factors
Journal
The international journal of cardiovascular imaging
ISSN: 1875-8312
Titre abrégé: Int J Cardiovasc Imaging
Pays: United States
ID NLM: 100969716
Informations de publication
Date de publication:
Oct 2020
Oct 2020
Historique:
received:
09
03
2020
accepted:
01
06
2020
pubmed:
9
6
2020
medline:
29
9
2020
entrez:
9
6
2020
Statut:
ppublish
Résumé
Global longitudinal strain (GLS) declines throughout adult-life as the LV remodels and adapts. Information on the impact of cardiac risk factors such as male sex, obesity, smoking status, hypertension, hypercholesterolemia, and diabetes on GLS. over time has not yet been investigated. The present prospective longitudinal study included 689 participants of the 4th and 5th Copenhagen City Heart Study who had GLS measured at both timepoints. Mean age was 51 years and 45% were male. All participants underwent two echocardiographic examinations median 10.4 (IQR: 10.2, 10.9) years apart. Average decline in GLS during follow-up was -0.7%. High age, male sex, high body mass index, and mean arterial blood pressure (MAP) proved to be significantly associated with an accelerated decline in GLS. In a multivariable regression model including all the investigated cardiovascular risk factors, age (stand. β-coef. = -0.10, P = 0.005), male sex (stand. β-coef. = -0.16, P < 0.001), and MAP (stand. β-coef. = -0.07, P = 0.009) were independent predictors of an accelerated decline in GLS during a 10-year period. Finally, the investigated risk factors had different regional impact after the same multivariable adjustments. Male sex had a significant impact on changes in longitudinal strain at the apical, mid-wall and basal segments, meanwhile MAP and age only accelerated changes in the mid-wall and basal longitudinal strain. In the general population age, male sex, and MAP are independent predictors of an accelerated decline in GLS over a 10-year period. Furthermore, MAP, male sex and age had different regional impact.
Identifiants
pubmed: 32507994
doi: 10.1007/s10554-020-01906-5
pii: 10.1007/s10554-020-01906-5
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1907-1916Références
Moran AE, Forouzanfar MH, Roth GA, Mensah GA, Ezzati M, Murray CJL, Naghavi M (1980) Temporal trends in ischemic heart disease mortality in 21 world regions, to 2010: the Global Burden of Disease 2010 study. Circulation 129(2014):1483–1492. https://doi.org/10.1161/CIRCULATIONAHA.113.004042
doi: 10.1161/CIRCULATIONAHA.113.004042
Savarese G, Lund LH (2017) Global Public Health Burden of Heart Failure. Card. Fail. Rev. 3:7–11. https://doi.org/10.15420/cfr.2016:25:2
doi: 10.15420/cfr.2016:25:2
pubmed: 28785469
pmcid: 5494150
Piepoli MF, Hoes AW, Agewall S, Albus C, Brotons C, Catapano AL, Cooney M-T, Corrà U, Cosyns B, Deaton C, Graham I, Hall MS, Hobbs FDR, Løchen M-L, Löllgen H, Marques-Vidal P, Perk J, Prescott E, Redon J, Richter DJ, Sattar N, Smulders Y, Tiberi M, van der Worp HB, van Dis I, Verschuren WMM, Binno S, ESC Scientific Document Group ( 2016) European Guidelines on cardiovascular disease prevention in clinical practice: The Sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of 10 societies and by invited experts)Developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation (EACPR). Eur. Heart J. 37(2016):2315–2381. https://doi.org/10.1093/eurheartj/ehw106
doi: 10.1093/eurheartj/ehw106
pubmed: 27222591
pmcid: 4986030
Kannel WB, McGee DL (1979) Diabetes and glucose tolerance as risk factors for cardiovascular disease: the Framingham study. Diabetes Care 2:120–126
doi: 10.2337/diacare.2.2.120
Wilson PW, D’Agostino RB, Levy D, Belanger AM, Silbershatz H, Kannel WB (1998) Prediction of coronary heart disease using risk factor categories. Circulation 97:1837–1847
doi: 10.1161/01.CIR.97.18.1837
Ponikowski P, Voors AA, Anker SD, Bueno H, Cleland JGF, Coats AJS, Falk V, González-Juanatey JR, Harjola V-P, Jankowska EA, Jessup M, Linde C, Nihoyannopoulos P, Parissis JT, Pieske B, Riley JP, Rosano GMC, Ruilope LM, Ruschitzka F, Rutten FH, van der Meer P, Filippatos G, McMurray JJV, Aboyans V, Achenbach S, Agewall S, Al-Attar N, Atherton JJ, Bauersachs J, John Camm A, Carerj S, Ceconi C, Coca A, Elliott P, Erol Ç, Ezekowitz J, Fernández-Golfín C, Fitzsimons D, Guazzi M, Guenoun M, Hasenfuss G, Hindricks G, Hoes AW, Iung B, Jaarsma T, Kirchhof P, Knuuti J, Kolh P, Konstantinides S, Lainscak M, Lancellotti P, Lip GYH, Maisano F, Mueller C, Petrie MC, Piepoli MF, Priori SG, Torbicki A, Tsutsui H, Veldhuisen V, Windecker DJS, Yancy C, Zamorano JL, Zamorano JL, Aboyans V, Achenbach S, Agewall S, Badimon L, Barón-Esquivias G, Baumgartner H, Bax JJ, Bueno H, Carerj S, Dean V, Erol Ç, Fitzsimons D, Gaemperli O, Kirchhof P, Kolh P, Lancellotti P, Lip GYH, Nihoyannopoulos P, Piepoli MF, Ponikowski P, Roffi M, Torbicki A, Vaz Carneiro A, Windecker S, Sisakian HS, Isayev E, Kurlianskaya A, Mullens W, Tokmakova M, Agathangelou P, Melenovsky V, Wiggers H, Hassanein M, Uuetoa T, Lommi J, Kostovska ES, Juillière Y, Aladashvili A, Luchner A, Chrysohoou C, Nyolczas N, Thorgeirsson G, Marc Weinstein J, Di Lenarda A, Aidargaliyeva N, Bajraktari G, Beishenkulov M, Kamzola G, Abdel-Massih T, Celutkiene J, Noppe S, Cassar A, Vataman E, Abir-Khalil S, vanPol P, Mo R, Straburzynska-Migaj E, Fonseca C, Chioncel O, Shlyakhto E, Otasevic P, Goncalvesová E, Lainscak M, Díaz Molina B, Schaufelberger M, Suter T, Yilmaz MB, Voronkov L, Davies C (2016) ESC Guidelines for the diagnosis and treatment of acute and chronic heart failureThe Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC)Developed with the special contribution of the Heart Failure Association (HFA) of the ESC. Eur Heart J 37(2016):2129–2200. https://doi.org/10.1093/eurheartj/ehw128
doi: 10.1093/eurheartj/ehw128
Conroy RM, Pyörälä K, Fitzgerald AP, Sans S, Menotti A, De Backer G, De Bacquer D, Ducimetière P, Jousilahti P, Keil U, Njølstad I, Oganov RG, Thomsen T, Tunstall-Pedoe H, Tverdal A, Wedel H, Whincup P, Wilhelmsen L, Graham IM (2003) SCORE project group, Estimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE project. Eur Heart J 24:987–1003
doi: 10.1016/S0195-668X(03)00114-3
D’Agostino RB, Vasan RS, Pencina MJ, Wolf PA, Cobain M, Massaro JM, Kannel WB (2008) General cardiovascular risk profile for use in primary care: the Framingham Heart Study. Circulation 117:743–753. https://doi.org/10.1161/CIRCULATIONAHA.107.699579
doi: 10.1161/CIRCULATIONAHA.107.699579
pubmed: 18212285
Goff DC, Lloyd-Jones DM, Bennett G, Coady S, D’Agostino RB, Gibbons R, Greenland P, Lackland DT, Levy D, O’Donnell CJ, Robinson JG, Schwartz JS, Shero ST, Smith SC, Sorlie P, Stone NJ, Wilson PWF, Jordan HS, Nevo L, Wnek J, Anderson JL, Halperin JL, Albert NM, Bozkurt B, Brindis RG, Curtis LH, DeMets D, Hochman JS, Kovacs RJ, Ohman EM, Pressler SJ, Sellke FW, Shen W-K, Smith SC, Tomaselli GF, A (2013) ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation 129(2014):S49–73. https://doi.org/10.1161/01.cir.0000437741.48606.98
doi: 10.1161/01.cir.0000437741.48606.98
pubmed: 24222018
Nikitin NP, Loh PH, de Silva R, Witte KKA, Lukaschuk EI, Parker A, Farnsworth TA, Alamgir FM, Clark AL, Cleland JGF (2006) Left ventricular morphology, global and longitudinal function in normal older individuals: a cardiac magnetic resonance study. Int J Cardiol 108:76–83. https://doi.org/10.1016/j.ijcard.2005.04.009
doi: 10.1016/j.ijcard.2005.04.009
pubmed: 16516701
Biering-Sørensen T, Biering-Sørensen SR, Olsen FJ, Sengeløv M, Jørgensen PG, Mogelvang R, Shah AM, Jensen JS (2017) Global Longitudinal Strain by Echocardiography Predicts Long-Term Risk of Cardiovascular Morbidity and Mortality in a Low-Risk General Population: The Copenhagen City Heart Study Cardiovasc. Imaging Circ. https://doi.org/10.1161/CIRCIMAGING.116.005521
doi: 10.1161/CIRCIMAGING.116.005521
Russo C, Jin Z, Elkind MSV, Rundek T, Homma S, Sacco RL, Di Tullio MR (2014) Prevalence and prognostic value of subclinical left ventricular systolic dysfunction by global longitudinal strain in a community-based cohort. Eur J Heart Fail 16:1301–1309. https://doi.org/10.1002/ejhf.154
doi: 10.1002/ejhf.154
pubmed: 25211239
pmcid: 4672867
Olsen FJ, Pedersen S, Jensen JS, Biering-Sørensen T (2016) Global longitudinal strain predicts incident atrial fibrillation and stroke occurrence after acute myocardial infarction. Medicine (Baltimore) 95:e5338. https://doi.org/10.1097/MD.0000000000005338
doi: 10.1097/MD.0000000000005338
Skaarup KG, Iversen A, Jørgensen PG, Olsen FJ, Grove GL, Jensen JS, Biering-Sørensen T (2018) Association between layer-specific global longitudinal strain and adverse outcomes following acute coronary syndrome. Eur Heart J Cardiovasc Imaging. https://doi.org/10.1093/ehjci/jey004
doi: 10.1093/ehjci/jey004
pubmed: 29617974
Sengeløv M, Jørgensen PG, Jensen JS, Bruun NE, Olsen FJ, Fritz-Hansen T, Nochioka K, Biering-Sørensen T (2015) Global Longitudinal Strain Is a Superior Predictor of All-Cause Mortality in Heart Failure With Reduced Ejection Fraction. JACC Cardiovasc Imaging 8:1351–1359. https://doi.org/10.1016/j.jcmg.2015.07.013
doi: 10.1016/j.jcmg.2015.07.013
pubmed: 26577264
Gosse P, Coulon P, Papaioannou G, Litalien J, Lemetayer P (2011) Impact of malignant arterial hypertension on the heart. J Hypertens 29:798–802. https://doi.org/10.1097/HJH.0b013e3283430b12
doi: 10.1097/HJH.0b013e3283430b12
pubmed: 21178780
Kuznetsova T, Herbots L, Richart T (2008) J D’hooge, L Thijs, RH Fagard, MC Herregods, JA Staessen, Left ventricular strain and strain rate in a general population. Eur. Heart J. 29:2014–2023. https://doi.org/10.1093/eurheartj/ehn280
doi: 10.1093/eurheartj/ehn280
pubmed: 18583396
Ng ACT, Prevedello F, Dolci G, Roos CJ, Djaberi R, Bertini M, Ewe SH, Allman C, Leung DY, Marsan NA, Delgado V, Bax JJ (2018) Impact of Diabetes and Increasing Body Mass Index Category on Left Ventricular Systolic and Diastolic Function. J Am Soc Echocardiogr Off Publ Am Soc Echocardiogr 31:916–925. https://doi.org/10.1016/j.echo.2018.02.012
doi: 10.1016/j.echo.2018.02.012
Leng Z, Li R, Li Y, Wang L, Wang Y, Yang Y (2017) Myocardial layer-specific analysis in patients with heterozygous familial hypercholesterolemia using speckle tracking echocardiography. Echocardiogr Mt Kisco N 34:390–396. https://doi.org/10.1111/echo.13442
doi: 10.1111/echo.13442
Mogelvang R, Sogaard P, Pedersen SA, Olsen NT, Schnohr P, Jensen JS (2009) Tissue Doppler echocardiography in persons with hypertension, diabetes, or ischaemic heart disease: the Copenhagen City Heart Study. Eur Heart J 30:731–739. https://doi.org/10.1093/eurheartj/ehn596
doi: 10.1093/eurheartj/ehn596
pubmed: 19176536
N.B. Schiller, P.M. Shah, M. Crawford, A. DeMaria, R. Devereux, H. Feigenbaum, H. Gutgesell, N. Reichek, D. Sahn, I. Schnittger, (1989) Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. American Society of Echocardiography Committee on Standards, Subcommittee on Quantitation of Two-Dimensional Echocardiograms. J Am Soc Echocardiogr Off Publ Am Soc Echocardiogr 2 (1989): 358–367.
Frederiksen CA, Juhl-Olsen P, Hermansen JF, Andersen NH, Sloth E (2015) Clinical utility of semi-automated estimation of ejection fraction at the point-of-care. Heart Lung Vessels 7:208–216
pubmed: 26495266
Cheng S, Larson MG, McCabe EL, Osypiuk E, Lehman BT, Stanchev P, Aragam J, Benjamin EJ, Solomon SD, Vasan RS (2013) Age- and sex-based reference limits and clinical correlates of myocardial strain and synchrony: the Framingham Heart Study. Circ Cardiovasc Imaging 6:692–699. https://doi.org/10.1161/CIRCIMAGING.112.000627
doi: 10.1161/CIRCIMAGING.112.000627
pubmed: 23917618
Kajstura J, Cheng W, Sarangarajan R, Li P, Li B, Nitahara JA, Chapnick S, Reiss K, Olivetti G, Anversa P (1996) Necrotic and apoptotic myocyte cell death in the aging heart of Fischer 344 rats. Am J Physiol 271:H1215–1228. https://doi.org/10.1152/ajpheart.1996.271.3.H1215
doi: 10.1152/ajpheart.1996.271.3.H1215
pubmed: 8853362
Tan YT, Wenzelburger F, Lee E, Heatlie G, Leyva F, Patel K, Frenneaux M, Sanderson JE (2009) The pathophysiology of heart failure with normal ejection fraction: exercise echocardiography reveals complex abnormalities of both systolic and diastolic ventricular function involving torsion, untwist, and longitudinal motion. J Am Coll Cardiol 54:36–46. https://doi.org/10.1016/j.jacc.2009.03.037
doi: 10.1016/j.jacc.2009.03.037
pubmed: 19555838
Xiao RP, Tomhave ED, Wang DJ, Ji X, Boluyt MO, Cheng H, Lakatta EG, Koch WJ (1998) Age-associated reductions in cardiac beta1- and beta2-adrenergic responses without changes in inhibitory G proteins or receptor kinases. J Clin Invest 101:1273–1282. https://doi.org/10.1172/JCI1335
doi: 10.1172/JCI1335
pubmed: 9502768
pmcid: 508681
Lundorff IJ, Sengeløv M (2018) P Godsk Jørgensen, S Pedersen, D Modin, N Eske Bruun, T Fritz-Hansen, J Skov Jensen, T Biering-Sørensen (2018) Echocardiographic Predictors of Mortality in Women With Heart Failure With Reduced Ejection Fraction. Circ Cardiovasc Imaging 11:008031. https://doi.org/10.1161/CIRCIMAGING.118.008031
doi: 10.1161/CIRCIMAGING.118.008031
Olivetti G, Giordano G, Corradi D, Melissari M, Lagrasta C, Gambert SR, Anversa P (1995) Gender differences and aging: effects on the human heart. J Am Coll Cardiol 26:1068–1079. https://doi.org/10.1016/0735-1097(95)00282-8
doi: 10.1016/0735-1097(95)00282-8
pubmed: 7560601
Ishizu T, Seo Y, Kameda Y, Kawamura R, Kimura T, Shimojo N, Xu D, Murakoshi N, Aonuma K (2014) Left ventricular strain and transmural distribution of structural remodeling in hypertensive heart disease. Hypertens Dallas Tex 1979(63):500–506. https://doi.org/10.1161/HYPERTENSIONAHA.113.02149
doi: 10.1161/HYPERTENSIONAHA.113.02149
Poulsen SH, Andersen NH, Heickendorff L, Mogensen CE (2005) Relation between plasma amino-terminal propeptide of procollagen type III and left ventricular longitudinal strain in essential hypertension. Heart Br Card Soc 91:624–629. https://doi.org/10.1136/hrt.2003.029702
doi: 10.1136/hrt.2003.029702
Cikes M, Sutherland GR, Anderson LJ, Bijnens BH (2010) The role of echocardiographic deformation imaging in hypertrophic myopathies. Nat Rev Cardiol 7:384–396. https://doi.org/10.1038/nrcardio.2010.56
doi: 10.1038/nrcardio.2010.56
pubmed: 20458340
Frohlich ED, Apstein C, Chobanian AV, Devereux RB, Dustan HP, Dzau V, Fauad-Tarazi F, Horan MJ, Marcus M, Massie B (1992) The heart in hypertension. N Engl J Med 327:998–1008. https://doi.org/10.1056/NEJM199210013271406
doi: 10.1056/NEJM199210013271406
pubmed: 1518549
Liu D, Hu K, Nordbeck P, Ertl G, Störk S, Weidemann F (2016) Longitudinal strain bull’s eye plot patterns in patients with cardiomyopathy and concentric left ventricular hypertrophy. Eur J Med Res 21:21. https://doi.org/10.1186/s40001-016-0216-y
doi: 10.1186/s40001-016-0216-y
pubmed: 27165726
pmcid: 4862218
Diaz T, Pencina MJ, Benjamin EJ, Aragam J, Fuller DL, Pencina KM, Levy D, Vasan RS (2009) Prevalence, clinical correlates, and prognosis of discrete upper septal thickening on echocardiography: the Framingham Heart Study. Echocardiogr Mt Kisco N 26:247–253. https://doi.org/10.1111/j.1540-8175.2008.00806.x
doi: 10.1111/j.1540-8175.2008.00806.x
Grossman W, Jones D, McLaurin LP (1975) Wall stress and patterns of hypertrophy in the human left ventricle. J Clin Invest 56:56–64. https://doi.org/10.1172/JCI108079
doi: 10.1172/JCI108079
pubmed: 124746
pmcid: 436555
Shah AM, Claggett B, Sweitzer NK, Shah SJ, Anand IS, Liu L, Pitt B, Pfeffer MA, Solomon SD (2015) Prognostic Importance of Impaired Systolic Function in Heart Failure With Preserved Ejection Fraction and the Impact of Spironolactone. Circulation 132:402–414. https://doi.org/10.1161/CIRCULATIONAHA.115.015884
doi: 10.1161/CIRCULATIONAHA.115.015884
pubmed: 26130119
pmcid: 4526442