Burden of disease associated with dietary exposure to carcinogenic aflatoxins in Portugal using human biomonitoring approach.
Aflatoxins
Biomarkers of exposure
Burden of disease
Human biomonitoring
Portugal
Journal
Food research international (Ottawa, Ont.)
ISSN: 1873-7145
Titre abrégé: Food Res Int
Pays: Canada
ID NLM: 9210143
Informations de publication
Date de publication:
08 2020
08 2020
Historique:
received:
17
02
2020
revised:
27
03
2020
accepted:
29
03
2020
entrez:
11
6
2020
pubmed:
11
6
2020
medline:
15
4
2021
Statut:
ppublish
Résumé
Human biomonitoring is an important tool to assess human exposure to chemicals, contributing to describe trends of exposure over time and to identify population groups that could be under risk. Aflatoxins are genotoxic and carcinogenic food contaminants causing hepatocellular carcinoma, the third leading cause of cancer deaths worldwide. In Portugal, scarce data are available regarding exposure to aflatoxins and no previous study used human biomonitoring data to comprehensively characterize the associated burden of disease. 24 h urine and first-morning urine paired samples were collected by 94 participants and were analyzed by liquid chromatography-tandem mass spectrometry for the quantitative determination of aflatoxins (B
Identifiants
pubmed: 32517894
pii: S0963-9969(20)30235-0
doi: 10.1016/j.foodres.2020.109210
pii:
doi:
Substances chimiques
Aflatoxins
0
Biomarkers
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
109210Informations de copyright
Copyright © 2020 Elsevier Ltd. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.