The impact of preoperative nutritional status on post-surgical complication and mortality rates in patients undergoing radical cystectomy for bladder cancer: a systematic review of the literature.


Journal

World journal of urology
ISSN: 1433-8726
Titre abrégé: World J Urol
Pays: Germany
ID NLM: 8307716

Informations de publication

Date de publication:
Apr 2021
Historique:
received: 12 05 2020
accepted: 29 05 2020
pubmed: 11 6 2020
medline: 7 10 2021
entrez: 11 6 2020
Statut: ppublish

Résumé

To investigate the impact of preoperative nutritional factors [body mass index (BMI)], hypoalbuminemia (< 3.5 g/dL, sarcopenia) on complication and mortality rates after radical cystectomy (RC) for bladder cancer. The PubMed database was systematically searched for studies investigating the effect of nutritional status on postoperative outcomes after RC. English-language articles published between March 2010 and March 2020 were reviewed. For statistical analyses odds ratios (ORs) and hazard ratios (HRs) weighted mean was applied. Overall, 81 studies were included. Twenty-nine studies were enrolled in the final analyses. Patients with a 25-29.9 kg/m High BMI, hypoalbuminemia, and sarcopenia significantly increased the complication rate after RC. Hypoalbuminemia predicted worse 3 year OS and sarcopenia predicted unfavorable 5 year CSS and OS. Preoperative assessment of RC patients' nutritional status is a useful tool to predict perioperative and survival outcomes.

Identifiants

pubmed: 32519225
doi: 10.1007/s00345-020-03291-z
pii: 10.1007/s00345-020-03291-z
doi:

Types de publication

Journal Article Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1045-1081

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Auteurs

Paola Irene Ornaghi (PI)

Department of Urology, Luzerner Kantonsspital, Lucerne, Switzerland.
Department of Urology, University of Verona, Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy.

Luca Afferi (L)

Department of Urology, Luzerner Kantonsspital, Lucerne, Switzerland.

Alessandro Antonelli (A)

Department of Urology, University of Verona, Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy.

Maria Angela Cerruto (MA)

Department of Urology, University of Verona, Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy.

Katia Odorizzi (K)

Department of Urology, University of Verona, Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy.

Alessandra Gozzo (A)

Department of Urology, University of Verona, Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy.

Livio Mordasini (L)

Department of Urology, Luzerner Kantonsspital, Lucerne, Switzerland.

Agostino Mattei (A)

Department of Urology, Luzerner Kantonsspital, Lucerne, Switzerland. agostino.mattei@luks.ch.

Philipp Baumeister (P)

Department of Urology, Luzerner Kantonsspital, Lucerne, Switzerland.

Julian Cornelius (J)

Department of Urology, Luzerner Kantonsspital, Lucerne, Switzerland.

Alessandro Tafuri (A)

Department of Urology, University of Verona, Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy.

Marco Moschini (M)

Department of Urology, Luzerner Kantonsspital, Lucerne, Switzerland.

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