A conserved evolutionary mechanism permits Δ9 desaturation of very-long-chain fatty acyl lipids.
chain length specificity
desaturase
enzyme
enzyme mutation
fatty acid metabolism
metalloenzyme
monoene
phospholipid
stearoyl-CoA desaturase
structural determinants
substrate specificity
very-long-chain fatty acid
Δ9 integral membrane desaturase
Journal
The Journal of biological chemistry
ISSN: 1083-351X
Titre abrégé: J Biol Chem
Pays: United States
ID NLM: 2985121R
Informations de publication
Date de publication:
07 08 2020
07 08 2020
Historique:
received:
06
05
2020
revised:
08
06
2020
pubmed:
13
6
2020
medline:
20
2
2021
entrez:
13
6
2020
Statut:
ppublish
Résumé
Δ9 fatty acyl desaturases introduce a
Identifiants
pubmed: 32527722
pii: S0021-9258(17)49223-4
doi: 10.1074/jbc.RA120.014258
pmc: PMC7415989
doi:
Substances chimiques
Fatty Acid Desaturases
EC 1.14.19.-
Banques de données
PDB
['4YMK']
Types de publication
Journal Article
Research Support, U.S. Gov't, Non-P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Pagination
11337-11345Déclaration de conflit d'intérêts
Conflict of interest—The authors declare that they have no conflicts of interest with the contents of this article.
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