Long Non-coding RNAs Involved in Pathogenic Infection.
bacteria
immune response
infection
long non-coding RNA
virus
Journal
Frontiers in genetics
ISSN: 1664-8021
Titre abrégé: Front Genet
Pays: Switzerland
ID NLM: 101560621
Informations de publication
Date de publication:
2020
2020
Historique:
received:
15
04
2019
accepted:
14
04
2020
entrez:
13
6
2020
pubmed:
13
6
2020
medline:
13
6
2020
Statut:
epublish
Résumé
Recently developed technologies have revealed that the genomes of many organisms produce transcripts that do not encode proteins. These are called non-coding RNAs. Long non-coding RNAs (lncRNAs) are important regulators of the expression of their target genes at the levels of transcription, translation, and degradation. Multiple studies have demonstrated a role for lncRNAs in various biological responses, including pathogenic infection. Upon pathogenic infection, the expression levels of lncRNAs are dynamically altered, suggesting that lncRNAs are involved in the host immune response or propagation of pathogens. In this review, we focused on host lncRNAs that are involved in pathogenic infection. Some host lncRNAs act as host defense molecules to prevent pathogenic proliferation, while others are utilized by the pathogen to enhance the propagation of pathogens.
Identifiants
pubmed: 32528521
doi: 10.3389/fgene.2020.00454
pmc: PMC7264421
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
454Informations de copyright
Copyright © 2020 Shirahama, Miki, Kaburaki and Akimitsu.
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