Nobuyoshi Akimitsu

Affiliations

Isotope Science Center, The University of Tokyo, Tokyo, 113-0032, Japan.

ORCID: 0000-0002-3190-2942

Publications (33)

Identification of a heat-inducible novel nuclear body containing the long noncoding RNA MALAT1.

Journal of cell science

Avec: Rena Onoguchi-Mizutani , Yoshitaka Kirikae , Yoko Ogura , Tony Gutschner , Sven Diederichs , Nobuyoshi Akimitsu

A histone modifier, ASXL1, interacts with NONO and is involved in paraspeckle formation in hematopoietic cells.

Cell reports

Avec: Keita Yamamoto , Susumu Goyama , Shuhei Asada , Takeshi Fujino , Taishi Yonezawa , Naru Sato , Reina Takeda , Akiho Tsuchiya , Tomofusa Fukuyama , Yosuke Tanaka , Akihiko Yokoyama , Hikaru Toya , Ayana Kon , Yasuhito Nannya , Rena Onoguchi-Mizutani , Shinichi Nakagawa , Tetsuro Hirose , Seishi Ogawa , Nobuyoshi Akimitsu , Toshio Kitamura

Vagus nerve stimulation even after injury ameliorates cisplatin-induced nephropathy via reducing macrophage infiltration.

Scientific reports

Avec: Rie Uni , Tsuyoshi Inoue , Yasuna Nakamura , Daichi Fukaya , Sho Hasegawa , Chia-Hsien Wu , Rie Fujii , Bongkod Surattichaiyakul , Wachirasek Peerapanyasut , Atsuko Ozeki , Nobuyoshi Akimitsu , Youichiro Wada , Masaomi Nangaku , Reiko Inagi

Systematic Analysis of Targets of Pumilio-Mediated mRNA Decay Reveals that PUM1 Repression by DNA Damage Activates Translesion Synthesis.

Cell reports

Avec: Toshimichi Yamada , Naoto Imamachi , Katsutoshi Imamura , Kenzui Taniue , Takeshi Kawamura , Yutaka Suzuki , Masami Nagahama , Nobuyoshi Akimitsu

Activation of Sympathetic Signaling in Macrophages Blocks Systemic Inflammation and Protects against Renal Ischemia-Reperfusion Injury.

Journal of the American Society of Nephrology : JASN

Avec: Sho Hasegawa , Tsuyoshi Inoue , Yasuna Nakamura , Daichi Fukaya , Rie Uni , Chia-Hsien Wu , Rie Fujii , Wachirasek Peerapanyasut , Akashi Taguchi , Takahide Kohro , Shintaro Yamada , Mikako Katagiri , Toshiyuki Ko , Seitaro Nomura , Atsuko Nakanishi Ozeki , Etsuo A Susaki , Hiroki R Ueda , Nobuyoshi Akimitsu , Youichiro Wada , Issei Komuro , Masaomi Nangaku , Reiko Inagi

Loss of the fragile X syndrome protein FMRP results in misregulation of nonsense-mediated mRNA decay.

Nature cell biology

Avec: Tatsuaki Kurosaki , Naoto Imamachi , Christoph Pröschel , Shuhei Mitsutomi , Rina Nagao , Nobuyoshi Akimitsu , Lynne E Maquat

Fusion Genes and RNAs in Cancer Development.

Non-coding RNA

Avec: Kenzui Taniue , Nobuyoshi Akimitsu

The role of micropeptides in biology.

Cellular and molecular life sciences : CMLS

Avec: Rui Vitorino , Sofia Guedes , Francisco Amado , Manuel Santos , Nobuyoshi Akimitsu

Identification of novel heat shock-induced long non-coding RNA in human cells.

Journal of biochemistry

Avec: Rena Onoguchi-Mizutani , Yoshihiro Kishi , Yoko Ogura , Yuuki Nishimura , Naoto Imamachi , Yutaka Suzuki , Satoru Miyazaki , Nobuyoshi Akimitsu

Exploration of Salmonella effector mutant strains on MTR4 and RRP6 degradation.

Bioscience trends

Avec: Xiaoning Sun , Kentaro Kawata , Atsuko Miki , Youichiro Wada , Masami Nagahama , Akiko Takaya , Nobuyoshi Akimitsu

Long Non-coding RNAs Involved in Pathogenic Infection.

Frontiers in genetics

Avec: Shintaro Shirahama , Atsuko Miki , Toshikatsu Kaburaki , Nobuyoshi Akimitsu

Contributions of regulated transcription and mRNA decay to the dynamics of gene expression.

Wiley interdisciplinary reviews. RNA

Avec: Toshimichi Yamada , Nobuyoshi Akimitsu

Pan-cancer methylome analysis for cancer diagnosis and classification of cancer cell of origin.

Cancer gene therapy

Avec: Dai Shimizu , Kenzui Taniue , Yusuke Matsui , Hiroshi Haeno , Hiromitsu Araki , Fumihito Miura , Mitsuko Fukunaga , Kenji Shiraishi , Yuji Miyamoto , Seiichi Tsukamoto , Aya Komine , Yuta Kobayashi , Akihiro Kitagawa , Yukihiro Yoshikawa , Kuniaki Sato , Tomoko Saito , Shuhei Ito , Takaaki Masuda , Atsushi Niida , Makoto Suzuki , Hideo Baba , Takashi Ito , Nobuyoshi Akimitsu , Yasuhiro Kodera , Koshi Mimori

RNA Exosome Component EXOSC4 Amplified in Multiple Cancer Types Is Required for the Cancer Cell Survival.

International journal of molecular sciences

Avec: Kenzui Taniue , Tanzina Tanu , Yuki Shimoura , Shuhei Mitsutomi , Han Han , Rika Kakisaka , Yusuke Ono , Nobue Tamamura , Kenji Takahashi , Youichiro Wada , Yusuke Mizukami , Nobuyoshi Akimitsu

Repression of PUM1-mediated mRNA decay activates translesion synthesis after DNA damage.

Molecular & cellular oncology

Avec: Toshimichi Yamada , Xiaoning Sun , Nobuyoshi Akimitsu

Increased PDGFRB and NF-κB signaling caused by highly prevalent somatic mutations in intracranial aneurysms.

Science translational medicine

Avec: Yasuyuki Shima , Shota Sasagawa , Nakao Ota , Rieko Oyama , Minoru Tanaka , Mie Kubota-Sakashita , Hirochika Kawakami , Mika Kobayashi , Naoko Takubo , Atsuko Nakanishi Ozeki , Xiaoning Sun , Yeon-Jeong Kim , Yoichiro Kamatani , Koichi Matsuda , Kazuhiro Maejima , Masashi Fujita , Kosumo Noda , Hiroyasu Kamiyama , Rokuya Tanikawa , Motoo Nagane , Junji Shibahara , Toru Tanaka , Yoshiyuki Rikitake , Nobuko Mataga , Satoru Takahashi , Kenjiro Kosaki , Hideyuki Okano , Tomomi Furihata , Ryo Nakaki , Nobuyoshi Akimitsu , Youichiro Wada , Toshihisa Ohtsuka , Hiroki Kurihara , Hiroyuki Kamiguchi , Shigeo Okabe , Masato Nakafuku , Tadafumi Kato , Hidewaki Nakagawa , Nobuhito Saito , Hirofumi Nakatomi

Click Chemistry Enables [

Bioconjugate chemistry

Avec: Ryota Imura , Jaewoong Jang , Atsuko Nakanishi Ozeki , Hiroyuki Takahashi , Hiroyuki Ida , Youichiro Wada , Yoshitaka Kumakura , Nobuyoshi Akimitsu

VISUALIZATION OF THE DNA REPAIR PROCESS IN MAMMALIAN CELLS TRANSFECTED WITH EGFP-EXPRESSING PLASMID DNA AFTER EXPOSURE TO X-RAYS IN VITRO.

Radiation protection dosimetry

Avec: Hiroki Nakaue , Yui Obata , Kiichi Kaminaga , Nobuyoshi Akimitsu , Akinari Yokoya

Stability of RNA sequences derived from the coronavirus genome in human cells.

Biochemical and biophysical research communications

Avec: Hiroyasu Wakida , Kentaro Kawata , Yuta Yamaji , Emi Hattori , Takaho Tsuchiya , Youichiro Wada , Haruka Ozaki , Nobuyoshi Akimitsu

The Functions and Unique Features of LncRNAs in Cancer Development and Tumorigenesis.

International journal of molecular sciences

Avec: Kenzui Taniue , Nobuyoshi Akimitsu

Expression of an X-Ray Irradiated EGFP-Expressing Plasmid Transfected into Nonirradiated Human Cells.

Radiation research

Avec: Yui Obata , Hiroki Nakaue , Keishiro Hirasaki , Nobuyoshi Akimitsu , Akinari Yokoya

Integrative omics indicate FMRP sequesters mRNA from translation and deadenylation in human neuronal cells.

Molecular cell

Avec: Tatsuaki Kurosaki , Shuhei Mitsutomi , Alexander Hewko , Nobuyoshi Akimitsu , Lynne E Maquat

LncRNA

PNAS nexus

Avec: Kenzui Taniue , Takeaki Oda , Tomoatsu Hayashi , Yuki Kamoshida , Yasuko Takeda , Anzu Sugawara , Yuki Shimoura , Lumi Negishi , Takeshi Nagashima , Mariko Okada-Hatakeyama , Yoshifumi Kawamura , Naoki Goshima , Nobuyoshi Akimitsu , Tetsu Akiyama

Metabolic labeling of RNA using multiple ribonucleoside analogs enables the simultaneous evaluation of RNA synthesis and degradation rates.

Genome research

Avec: Kentaro Kawata , Hiroyasu Wakida , Toshimichi Yamada , Kenzui Taniue , Han Han , Masahide Seki , Yutaka Suzuki , Nobuyoshi Akimitsu

Identification of 2H phosphoesterase superfamily proteins with 2'-CPDase activity.

Biochimie

Avec: Shuhei Mitsutomi , Nobuyoshi Akimitsu , Kazuhisa Sekimizu , Chikara Kaito

hnRNPH1-MTR4 complex-mediated regulation of

RNA biology

Avec: Tanzina Tanu , Kenzui Taniue , Katsutoshi Imamura , Rena Onoguchi-Mizutani , Han Han , Torben Heick Jensen , Nobuyoshi Akimitsu

Long noncoding RNA U90926 is crucial for herpes simplex virus type 1 proliferation in murine retinal photoreceptor cells.

Scientific reports

Avec: Shintaro Shirahama , Rena Onoguchi-Mizutani , Kentaro Kawata , Kenzui Taniue , Atsuko Miki , Akihisa Kato , Yasushi Kawaguchi , Rie Tanaka , Toshikatsu Kaburaki , Hidetoshi Kawashima , Yoshihiro Urade , Makoto Aihara , Nobuyoshi Akimitsu

Identification and analysis of short open reading frames (sORFs) in the initially annotated noncoding RNA LINC00493 from human cells.

Journal of biochemistry

Avec: Fouzia Yeasmin , Naoto Imamachi , Tanzina Tanu , Kenzui Taniue , Takeshi Kawamura , Tetsushi Yada , Nobuyoshi Akimitsu

Aberrant phase separation and cancer.

The FEBS journal

Avec: Kenzui Taniue , Nobuyoshi Akimitsu

Long noncoding RNA and phase separation in cellular stress response.

Journal of biochemistry

Avec: Rena Onoguchi-Mizutani , Nobuyoshi Akimitsu

Human U90926 orthologous long non-coding RNA as a novel biomarker for visual prognosis in herpes simplex virus type-1 induced acute retinal necrosis.

Scientific reports

Avec: Shintaro Shirahama , Kenzui Taniue , Shuhei Mitsutomi , Rie Tanaka , Toshikatsu Kaburaki , Tomohito Sato , Masaru Takeuchi , Hidetoshi Kawashima , Yoshihiro Urade , Makoto Aihara , Nobuyoshi Akimitsu

Multi-omics analysis using antibody-based in situ biotinylation technique suggests the mechanism of Cajal body formation.

Cell reports

Avec: Keisuke Noguchi , Hidefumi Suzuki , Ryota Abe , Keiko Horiuchi , Rena Onoguchi-Mizutani , Nobuyoshi Akimitsu , Shintaro Ogawa , Tomohiko Akiyama , Yoko Ike , Yoko Ino , Yayoi Kimura , Akihide Ryo , Hiroshi Doi , Fumiaki Tanaka , Yutaka Suzuki , Atsushi Toyoda , Yuki Yamaguchi , Hidehisa Takahashi

The MTR4/hnRNPK complex surveils aberrant polyadenylated RNAs with multiple exons.

Nature communications

Avec: Kenzui Taniue , Anzu Sugawara , Chao Zeng , Han Han , Xinyue Gao , Yuki Shimoura , Atsuko Nakanishi Ozeki , Rena Onoguchi-Mizutani , Masahide Seki , Yutaka Suzuki , Michiaki Hamada , Nobuyoshi Akimitsu

Réseau de co-auteurs

Kenzui Taniue 13 collaborations

Rena Onoguchi-Mizutani 8 collaborations

Youichiro Wada 7 collaborations

Yutaka Suzuki 5 collaborations

Shuhei Mitsutomi 5 collaborations

Toshimichi Yamada 4 collaborations

Naoto Imamachi 4 collaborations

Atsuko Nakanishi Ozeki 4 collaborations

Kentaro Kawata 4 collaborations

Han Han 4 collaborations

Xiaoning Sun 3 collaborations

Atsuko Miki 3 collaborations

Shintaro Shirahama 3 collaborations

Toshikatsu Kaburaki 3 collaborations

Tanzina Tanu 3 collaborations

Yuki Shimoura 3 collaborations

Yoko Ogura 2 collaborations

Rie Uni 2 collaborations

Tsuyoshi Inoue 2 collaborations

Yasuna Nakamura 2 collaborations

Daichi Fukaya 2 collaborations

Sho Hasegawa 2 collaborations

Chia-Hsien Wu 2 collaborations

Rie Fujii 2 collaborations

Wachirasek Peerapanyasut 2 collaborations

Masaomi Nangaku 2 collaborations

Reiko Inagi 2 collaborations

Katsutoshi Imamura 2 collaborations

Takeshi Kawamura 2 collaborations

Masami Nagahama 2 collaborations

Tatsuaki Kurosaki 2 collaborations

Lynne E Maquat 2 collaborations

Hiroki Nakaue 2 collaborations

Yui Obata 2 collaborations

Akinari Yokoya 2 collaborations

Hiroyasu Wakida 2 collaborations

Anzu Sugawara 2 collaborations

Masahide Seki 2 collaborations

Rie Tanaka 2 collaborations

Hidetoshi Kawashima 2 collaborations

Yoshihiro Urade 2 collaborations

Makoto Aihara 2 collaborations

Yoshitaka Kirikae 1 collaboration

Tony Gutschner 1 collaboration

Sven Diederichs 1 collaboration

Keita Yamamoto 1 collaboration

Susumu Goyama 1 collaboration

Shuhei Asada 1 collaboration

Takeshi Fujino 1 collaboration

Taishi Yonezawa 1 collaboration

Naru Sato 1 collaboration

Reina Takeda 1 collaboration

Akiho Tsuchiya 1 collaboration

Tomofusa Fukuyama 1 collaboration

Yosuke Tanaka 1 collaboration

Akihiko Yokoyama 1 collaboration

Hikaru Toya 1 collaboration

Ayana Kon 1 collaboration

Yasuhito Nannya 1 collaboration

Shinichi Nakagawa 1 collaboration

Tetsuro Hirose 1 collaboration

Seishi Ogawa 1 collaboration

Toshio Kitamura 1 collaboration

Bongkod Surattichaiyakul 1 collaboration

Atsuko Ozeki 1 collaboration

Akashi Taguchi 1 collaboration

Takahide Kohro 1 collaboration

Shintaro Yamada 1 collaboration

Mikako Katagiri 1 collaboration

Toshiyuki Ko 1 collaboration

Seitaro Nomura 1 collaboration

Etsuo A Susaki 1 collaboration

Hiroki R Ueda 1 collaboration

Issei Komuro 1 collaboration

Christoph Pröschel 1 collaboration

Rina Nagao 1 collaboration

Rui Vitorino 1 collaboration

Sofia Guedes 1 collaboration

Francisco Amado 1 collaboration

Manuel Santos 1 collaboration

Yoshihiro Kishi 1 collaboration

Yuuki Nishimura 1 collaboration

Satoru Miyazaki 1 collaboration

Akiko Takaya 1 collaboration

Dai Shimizu 1 collaboration

Yusuke Matsui 1 collaboration

Hiroshi Haeno 1 collaboration

Hiromitsu Araki 1 collaboration

Fumihito Miura 1 collaboration

Mitsuko Fukunaga 1 collaboration

Kenji Shiraishi 1 collaboration

Yuji Miyamoto 1 collaboration

Seiichi Tsukamoto 1 collaboration

Aya Komine 1 collaboration

Yuta Kobayashi 1 collaboration

Akihiro Kitagawa 1 collaboration

Yukihiro Yoshikawa 1 collaboration

Kuniaki Sato 1 collaboration

Tomoko Saito 1 collaboration

Shuhei Ito 1 collaboration

Takaaki Masuda 1 collaboration

Atsushi Niida 1 collaboration

Makoto Suzuki 1 collaboration

Hideo Baba 1 collaboration

Takashi Ito 1 collaboration

Yasuhiro Kodera 1 collaboration

Koshi Mimori 1 collaboration

Rika Kakisaka 1 collaboration

Yusuke Ono 1 collaboration

Nobue Tamamura 1 collaboration

Kenji Takahashi 1 collaboration

Yusuke Mizukami 1 collaboration

Yasuyuki Shima 1 collaboration

Shota Sasagawa 1 collaboration

Nakao Ota 1 collaboration

Rieko Oyama 1 collaboration

Minoru Tanaka 1 collaboration

Mie Kubota-Sakashita 1 collaboration

Hirochika Kawakami 1 collaboration

Mika Kobayashi 1 collaboration

Naoko Takubo 1 collaboration

Yeon-Jeong Kim 1 collaboration

Yoichiro Kamatani 1 collaboration

Koichi Matsuda 1 collaboration

Kazuhiro Maejima 1 collaboration

Masashi Fujita 1 collaboration

Kosumo Noda 1 collaboration

Hiroyasu Kamiyama 1 collaboration

Rokuya Tanikawa 1 collaboration

Motoo Nagane 1 collaboration

Junji Shibahara 1 collaboration

Toru Tanaka 1 collaboration

Yoshiyuki Rikitake 1 collaboration

Nobuko Mataga 1 collaboration

Satoru Takahashi 1 collaboration

Kenjiro Kosaki 1 collaboration

Hideyuki Okano 1 collaboration

Tomomi Furihata 1 collaboration

Ryo Nakaki 1 collaboration

Toshihisa Ohtsuka 1 collaboration

Hiroki Kurihara 1 collaboration

Hiroyuki Kamiguchi 1 collaboration

Shigeo Okabe 1 collaboration

Masato Nakafuku 1 collaboration

Tadafumi Kato 1 collaboration

Hidewaki Nakagawa 1 collaboration

Nobuhito Saito 1 collaboration

Hirofumi Nakatomi 1 collaboration

Ryota Imura 1 collaboration

Jaewoong Jang 1 collaboration

Hiroyuki Takahashi 1 collaboration

Hiroyuki Ida 1 collaboration

Yoshitaka Kumakura 1 collaboration

Kiichi Kaminaga 1 collaboration

Yuta Yamaji 1 collaboration

Emi Hattori 1 collaboration

Takaho Tsuchiya 1 collaboration

Haruka Ozaki 1 collaboration

Keishiro Hirasaki 1 collaboration

Alexander Hewko 1 collaboration

Takeaki Oda 1 collaboration

Tomoatsu Hayashi 1 collaboration

Yuki Kamoshida 1 collaboration

Yasuko Takeda 1 collaboration

Lumi Negishi 1 collaboration

Takeshi Nagashima 1 collaboration

Mariko Okada-Hatakeyama 1 collaboration

Yoshifumi Kawamura 1 collaboration

Naoki Goshima 1 collaboration

Tetsu Akiyama 1 collaboration

Kazuhisa Sekimizu 1 collaboration

Chikara Kaito 1 collaboration

Torben Heick Jensen 1 collaboration

Akihisa Kato 1 collaboration

Yasushi Kawaguchi 1 collaboration

Fouzia Yeasmin 1 collaboration

Tetsushi Yada 1 collaboration

Tomohito Sato 1 collaboration

Masaru Takeuchi 1 collaboration

Keisuke Noguchi 1 collaboration

Hidefumi Suzuki 1 collaboration

Ryota Abe 1 collaboration

Keiko Horiuchi 1 collaboration

Shintaro Ogawa 1 collaboration

Tomohiko Akiyama 1 collaboration

Yoko Ike 1 collaboration

Yoko Ino 1 collaboration

Yayoi Kimura 1 collaboration

Akihide Ryo 1 collaboration

Hiroshi Doi 1 collaboration

Fumiaki Tanaka 1 collaboration

Atsushi Toyoda 1 collaboration

Yuki Yamaguchi 1 collaboration

Hidehisa Takahashi 1 collaboration

Chao Zeng 1 collaboration

Xinyue Gao 1 collaboration

Michiaki Hamada 1 collaboration