Zinc Phthalocyanine Photochemistry by Raman Imaging, Fluorescence Spectroscopy and Femtosecond Spectroscopy in Normal and Cancerous Human Colon Tissues and Single Cells.


Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
10 Jun 2020
Historique:
received: 04 05 2020
revised: 08 06 2020
accepted: 09 06 2020
entrez: 14 6 2020
pubmed: 14 6 2020
medline: 13 2 2021
Statut: epublish

Résumé

Photodynamic therapy is a clinically approved alternative method for cancer treatment in which a combination of nontoxic drugs known as photosensitizers and oxygen is used. Despite intensive investigations and encouraging results, zinc phthalocyanines (ZnPcs) have not yet been approved as photosensitizers for clinical use. Label-free Raman imaging of nonfixed and unstained normal and cancerous colon human tissues and normal human CCD18-Co and cancerous CaCo-2 cell lines, without and after adding ZnPcS

Identifiants

pubmed: 32531903
pii: molecules25112688
doi: 10.3390/molecules25112688
pmc: PMC7321347
pii:
doi:

Substances chimiques

Indoles 0
Isoindoles 0
Organometallic Compounds 0
Zinc Compounds 0
Zn(II)-phthalocyanine 14320-04-8

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : The National Science Centre Poland
ID : UMO-2017/25/B/ST4/01788

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Auteurs

Beata Brozek-Pluska (B)

Laboratory of Laser Molecular Spectroscopy, Institute of Applied Radiation Chemistry, Lodz University of Technology, Wroblewskiego 15, 93-590 Lodz, Poland.

Arkadiusz Jarota (A)

Laboratory of Laser Molecular Spectroscopy, Institute of Applied Radiation Chemistry, Lodz University of Technology, Wroblewskiego 15, 93-590 Lodz, Poland.

Rafal Kania (R)

Laboratory of Laser Molecular Spectroscopy, Institute of Applied Radiation Chemistry, Lodz University of Technology, Wroblewskiego 15, 93-590 Lodz, Poland.

Halina Abramczyk (H)

Laboratory of Laser Molecular Spectroscopy, Institute of Applied Radiation Chemistry, Lodz University of Technology, Wroblewskiego 15, 93-590 Lodz, Poland.

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Classifications MeSH