Microglia-released leukotriene B

Animals Brain / immunology Cell Line Cerebral Hemorrhage / immunology Cytokines / genetics Humans Leukotriene B4 / immunology Male Mice, Inbred C57BL Microglia / immunology Neutrophil Infiltration
Intracerebral hemorrhage Leukotriene B(4) Microglia Neutrophil

Journal

International immunopharmacology
ISSN: 1878-1705
Titre abrégé: Int Immunopharmacol
Pays: Netherlands
ID NLM: 100965259

Informations de publication

Date de publication:
Aug 2020
Historique:
received: 31 01 2020
revised: 19 05 2020
accepted: 04 06 2020
pubmed: 17 6 2020
medline: 22 4 2021
entrez: 17 6 2020
Statut: ppublish

Résumé

Intracerebral hemorrhage (ICH) from blood vessel rupture results in parenchymal hematoma formation and neuroinflammation, ultimately leading to neurodegeneration. Several lines of evidence suggest that the severity of ICH-induced neural damage is exacerbated by infiltration of T-cells, monocytes, and especially neutrophils into the hematoma. Neutrophil migration is regulated by chemokines, formyl peptides, and leukotriene B

Identifiants

DOI: 10.1016/j.intimp.2020.106678 PMID: 32544870
pubmed: 32544870
pii: S1567-5769(20)30284-8
doi: 10.1016/j.intimp.2020.106678
pii:
doi:

Substances chimiques

Cytokines 0
Leukotriene B4 1HGW4DR56D

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

106678

Informations de copyright

Copyright © 2020 Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest None.

Auteurs

Masanori Hijioka (M)

Laboratory of Pharmacology and Neurobiology, College of Pharmaceutical Sciences, Ritsumeikan University, 1-1-1 Noji-Higashi, Kusatsu, Shiga 525-8577, Japan. Electronic address: m-hiji@fc.ritsumei.ac.jp.

Risa Futokoro (R)

Laboratory of Pharmacology and Neurobiology, College of Pharmaceutical Sciences, Ritsumeikan University, 1-1-1 Noji-Higashi, Kusatsu, Shiga 525-8577, Japan.

Takayo Ohto-Nakanishi (T)

Lipidome Lab Co., Ltd., Akita 010-0825, Japan.

Hiroki Nakanishi (H)

Lipidome Lab Co., Ltd., Akita 010-0825, Japan; Research Center for Biosignaling, Akita University, Akita 010-8543, Japan.

Hiroshi Katsuki (H)

Department of Chemico-Pharmacological Sciences, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto 862-0973, Japan.

Yoshihisa Kitamura (Y)

Laboratory of Pharmacology and Neurobiology, College of Pharmaceutical Sciences, Ritsumeikan University, 1-1-1 Noji-Higashi, Kusatsu, Shiga 525-8577, Japan.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Microglia-released leukotriene B
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Microglia-released leukotriene B
questionsmedicales.fr › Cellules › Cellules cultivées › Lignée cellulaire › Microglia-released leukotriene B
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Hémorragie › Hémorragies intracrâniennes › Hémorragie cérébrale › Microglia-released leukotriene B
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Microglia-released leukotriene B
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Microglia-released leukotriene B
questionsmedicales.fr › Facteurs biologiques › Médiateurs de l'inflammation › Autacoïdes › Éicosanoïdes › Leucotriènes › Leucotriène B4 › Microglia-released leukotriene B
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée C57BL › Microglia-released leukotriene B
questionsmedicales.fr › Cellules › Névroglie › Microglie › Microglia-released leukotriene B
questionsmedicales.fr › Phénomènes du système immunitaire › Infiltration par les neutrophiles › Microglia-released leukotriene B