Synthesis and Antimicrobial Studies of Coumarin-Substituted Pyrazole Derivatives as Potent Anti-


Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
15 Jun 2020
Historique:
received: 21 05 2020
revised: 09 06 2020
accepted: 12 06 2020
entrez: 19 6 2020
pubmed: 19 6 2020
medline: 17 2 2021
Statut: epublish

Résumé

In this paper, synthesis and antimicrobial studies of 31 novel coumarin-substituted pyrazole derivatives are reported. Some of these compounds have shown potent activity against methicillin-resistant

Identifiants

pubmed: 32549248
pii: molecules25122758
doi: 10.3390/molecules25122758
pmc: PMC7356691
pii:
doi:

Substances chimiques

Anti-Bacterial Agents 0
Anti-Infective Agents 0
Coumarins 0
Pyrazoles 0
pyrazole 3QD5KJZ7ZJ
coumarin A4VZ22K1WT

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Arkansas Biosciences Institute
ID : mini-200035
Organisme : NIGMS NIH HHS
ID : P20 GM103429
Pays : United States

Références

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J Med Chem. 2020 Jun 25;63(12):6303-6314
pubmed: 32267691
Eur J Med Chem. 2017 Jan 5;125:551-564
pubmed: 27718471
Eur J Med Chem. 2016 Sep 14;120:170-201
pubmed: 27191614
Medchemcomm. 2019 Mar 14;10(8):1231-1241
pubmed: 31534648
Molecules. 2019 May 29;24(11):
pubmed: 31146470
Bioorg Med Chem Lett. 2018 Sep 15;28(17):2914-2919
pubmed: 30017319
Bioorg Chem. 2020 Jan;94:103434
pubmed: 31812263
Molecules. 2018 May 20;23(5):
pubmed: 29783770
Drug Des Devel Ther. 2016 Oct 31;10:3529-3543
pubmed: 27826185
Bioorg Med Chem Lett. 2017 Feb 1;27(3):387-392
pubmed: 28065568

Auteurs

Rawan Alnufaie (R)

Department of Chemistry and Physics, College of Science and Mathematics, Arkansas State University, Jonesboro, AR 72467, USA.

Hansa Raj Kc (H)

Department of Chemistry and Physics, College of Science and Mathematics, Arkansas State University, Jonesboro, AR 72467, USA.

Nickolas Alsup (N)

Department of Chemistry and Physics, College of Science and Mathematics, Arkansas State University, Jonesboro, AR 72467, USA.

Jedidiah Whitt (J)

Department of Chemistry and Physics, College of Science and Mathematics, Arkansas State University, Jonesboro, AR 72467, USA.

Steven Andrew Chambers (S)

Department of Chemistry and Physics, College of Science and Mathematics, Arkansas State University, Jonesboro, AR 72467, USA.

David Gilmore (D)

Department of Biological Sciences, College of Science and Mathematics, Arkansas State University, Jonesboro, AR 72467, USA.

Mohammad A Alam (MA)

Department of Chemistry and Physics, College of Science and Mathematics, Arkansas State University, Jonesboro, AR 72467, USA.

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Classifications MeSH