RNAi-mediated control of CRISPR functions.
Animals
Anti-Bacterial Agents
/ pharmacology
CRISPR-Cas Systems
/ genetics
Cell Line
Clustered Regularly Interspaced Short Palindromic Repeats
/ genetics
Enoxacin
/ pharmacology
Gene Editing
/ methods
Humans
Mice
Mice, Inbred C57BL
MicroRNAs
/ genetics
Models, Animal
RNA Interference
/ drug effects
RNA, Guide, Kinetoplastida
/ genetics
CRISPR switch
artificial miRNA
enoxacin
miRNA sponge
Journal
Theranostics
ISSN: 1838-7640
Titre abrégé: Theranostics
Pays: Australia
ID NLM: 101552395
Informations de publication
Date de publication:
2020
2020
Historique:
received:
13
02
2020
accepted:
30
04
2020
entrez:
20
6
2020
pubmed:
20
6
2020
medline:
19
5
2021
Statut:
epublish
Résumé
CRISPR-Cas9 has become a versatile tool for genome editing and regulation, and strategies to effectively control its activity have attracted much attention. RNAi, also a gene-regulating tool, is used as another mechanism by which eukaryotes resist the invasion of foreign genetic material.
Identifiants
pubmed: 32550896
doi: 10.7150/thno.44880
pii: thnov10p6661
pmc: PMC7295050
doi:
Substances chimiques
Anti-Bacterial Agents
0
MicroRNAs
0
RNA, Guide
0
Enoxacin
325OGW249P
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
6661-6673Informations de copyright
© The author(s).
Déclaration de conflit d'intérêts
Competing Interests: The authors have declared that no competing interest exists.
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