A newly identified duplex RNA unwinding activity of archaeal RNase J depends on processive exoribonucleolysis coupled steric occlusion by its structural archaeal loops.


Journal

RNA biology
ISSN: 1555-8584
Titre abrégé: RNA Biol
Pays: United States
ID NLM: 101235328

Informations de publication

Date de publication:
10 2020
Historique:
pubmed: 20 6 2020
medline: 9 7 2021
entrez: 20 6 2020
Statut: ppublish

Résumé

RNase J is a prokaryotic 5'-3' exo/endoribonuclease that functions in mRNA decay and rRNA maturation. Here, we report a novel duplex unwinding activity of mpy-RNase J, an archaeal RNase J from

Identifiants

pubmed: 32552320
doi: 10.1080/15476286.2020.1777379
pmc: PMC7549665
doi:

Substances chimiques

RNA, Archaeal 0
RNA, Double-Stranded 0
Ribonucleases EC 3.1.-

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1480-1491

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Auteurs

Jie Li (J)

State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences , Beijing, PR China.
Colleges of Life Sciences, University of Chinese Academy of Sciences , Beijing, China.

Yanjie Hou (Y)

Institute of Biophysics, Chinese Academy of Sciences , Beijing, PR China.

Xien Gu (X)

School of Basic Medical Sciences, Hubei University of Medicine , Shiyan, China.

Lei Yue (L)

State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences , Beijing, PR China.
Colleges of Life Sciences, University of Chinese Academy of Sciences , Beijing, China.

Lu Guo (L)

State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences , Beijing, PR China.

Defeng Li (D)

State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences , Beijing, PR China.
Colleges of Life Sciences, University of Chinese Academy of Sciences , Beijing, China.

Xiuzhu Dong (X)

State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences , Beijing, PR China.
Colleges of Life Sciences, University of Chinese Academy of Sciences , Beijing, China.

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Classifications MeSH