Search for an epigenetic biomarker in ADHD diagnosis, based on the DAT1 gene 5'-UTR methylation: a new possible approach.
5’-UTR motifs
CpG epigenetic marker
DNA opposite strand
Dopamine transporter (DAT)
Journal
Psychiatry research
ISSN: 1872-7123
Titre abrégé: Psychiatry Res
Pays: Ireland
ID NLM: 7911385
Informations de publication
Date de publication:
09 2020
09 2020
Historique:
received:
03
04
2020
revised:
20
05
2020
accepted:
28
05
2020
pubmed:
20
6
2020
medline:
23
12
2020
entrez:
20
6
2020
Statut:
ppublish
Résumé
Attention Deficit/Hyperactivity Disorder (ADHD) is the most common neuro-developmental alteration in childhood. To date, its diagnosis is exclusively clinical, however recent studies focused on searching for objective biomarkers. We recently reported a selective alteration of DNA methylation in the 5'-UTR of dopamine transporter (DAT1) gene, in a
Identifiants
pubmed: 32554184
pii: S0165-1781(20)30775-7
doi: 10.1016/j.psychres.2020.113154
pii:
doi:
Substances chimiques
Dopamine Plasma Membrane Transport Proteins
0
Genetic Markers
0
SLC6A3 protein, human
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
113154Informations de copyright
Copyright © 2020 Elsevier B.V. All rights reserved.