Analysis of Temperature-Dependent H/D Exchange Mass Spectrometry Experiments.

Animals Heart Horses Hydrogen Deuterium Exchange-Mass Spectrometry Myoglobin / analysis Temperature

Journal

Analytical chemistry
ISSN: 1520-6882
Titre abrégé: Anal Chem
Pays: United States
ID NLM: 0370536

Informations de publication

Date de publication:
21 07 2020
Historique:
pubmed: 20 6 2020
medline: 16 2 2021
entrez: 20 6 2020
Statut: ppublish

Résumé

H/D exchange (HDX) mass spectrometry (MS) is a widely used technique for interrogating protein structure and dynamics. Backbone HDX is mediated by opening/closing (unfolding/refolding) fluctuations. In traditional HDX-MS, proteins are incubated in D

Identifiants

DOI: 10.1021/acs.analchem.0c01828 PMID: 32558545
pubmed: 32558545
doi: 10.1021/acs.analchem.0c01828
doi:

Substances chimiques

Myoglobin 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

10058-10067

Auteurs

Nastaran N Tajoddin (NN)

Department of Chemistry, The University of Western Ontario, London, Ontario N6A 5B7, Canada.

Lars Konermann (L)

Department of Chemistry, The University of Western Ontario, London, Ontario N6A 5B7, Canada.
ORCID: 0000-0002-5283-3165

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Analysis of Temperature-Dependent H/D Exchange...
questionsmedicales.fr › Système cardiovasculaire › Coeur › Analysis of Temperature-Dependent H/D Exchange...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Perissodactyla › Equidae › Equus caballus › Analysis of Temperature-Dependent H/D Exchange...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Spectrométrie de masse › Échange hydrogène/deutérium couplé à la spectrométrie de masse › Analysis of Temperature-Dependent H/D Exchange...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Hémoprotéines › Globines › Myoglobine › Analysis of Temperature-Dependent H/D Exchange...
questionsmedicales.fr › Environnement et santé publique › Environnement › Concepts météorologiques › Atmosphère › Temps (météorologie) › Température › Analysis of Temperature-Dependent H/D Exchange...