Recent progress of antibacterial natural products: Future antibiotics candidates.

Anti-Bacterial Agents / pharmacology Biological Products / pharmacology Drug Discovery Microbial Sensitivity Tests
Antibacterial Drug Candidates Natural Products

Journal

Bioorganic chemistry
ISSN: 1090-2120
Titre abrégé: Bioorg Chem
Pays: United States
ID NLM: 1303703

Informations de publication

Date de publication:
08 2020
Historique:
received: 05 04 2020
revised: 01 05 2020
accepted: 06 05 2020
pubmed: 20 6 2020
medline: 12 3 2021
entrez: 20 6 2020
Statut: ppublish

Résumé

The discovery of novel antibacterial molecules plays a key role in solving the current antibiotic crisis issue. Natural products have long been an important source of drug discovery. Herein, we reviewed 256 natural products from 11 structural classes in the period of 2016-01/2020, which were selected by SciFinder with new compounds or new structures and MICs lower than 10 μg/mL or 10 μM as criterions. This review will provide some effective antibacterial lead compounds for medicinal chemists, which will promote the antibiotics research based on natural products to the next level.

Identifiants

DOI: 10.1016/j.bioorg.2020.103922 PMID: 32559577
pubmed: 32559577
pii: S0045-2068(20)30787-2
doi: 10.1016/j.bioorg.2020.103922
pii:
doi:

Substances chimiques

Anti-Bacterial Agents 0
Biological Products 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

103922

Informations de copyright

Copyright © 2020 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declared that there is no conflict of interest.

Auteurs

Jiangkun Dai (J)

College of Veterinary Medicine, Northwest A&F University, Shaanxi, China(1); State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Taipa, Macau, China(1); School of Life Science and Technology, Weifang Medical University, Shandong, China(1). Electronic address: daijkun@hotmail.com.

Rui Han (R)

College of Chemistry & Pharmacy, Northwest A&F University, Shaanxi, China(1).

Yujie Xu (Y)

College of Chemistry & Pharmacy, Northwest A&F University, Shaanxi, China(1).

Na Li (N)

College of Food Science and Technology, Northwest University, Xi'an, China(1). Electronic address: nwuln@nwu.edu.cn.

Junru Wang (J)

College of Veterinary Medicine, Northwest A&F University, Shaanxi, China(1); College of Chemistry & Pharmacy, Northwest A&F University, Shaanxi, China(1). Electronic address: wangjr07@163.com.

Wenjia Dan (W)

School of Life Science and Technology, Weifang Medical University, Shandong, China(1); College of Chemistry & Pharmacy, Northwest A&F University, Shaanxi, China(1). Electronic address: dwj586@163.com.

Articles similaires

Vancomycin-associated DRESS demonstrates delay in AST abnormalities.

Ahmed Hussein, Kateri L Schoettinger, Jourdan Hydol-Smith et al.
1.00
Humans Drug Hypersensitivity Syndrome Vancomycin Female Male

Management of the infected total elbow arthroplasty.

Joaquin Sanchez-Sotelo
1.00
Humans Arthroplasty, Replacement, Elbow Prosthesis-Related Infections Debridement Anti-Bacterial Agents

Mathematical modeling of vancomycin release from Poly-L-Lactic Acid-Coated implants.

Papon Thamvasupong, Kwanchanok Viravaidya-Pasuwat
1.00
Vancomycin Polyesters Anti-Bacterial Agents Models, Theoretical Drug Liberation

Menthol as an effective inhibitor of quorum sensing and biofilm formation in Candida albicans and Candida glabrata by targeting the transcriptional repressor TUP1.

Pouria Khodavandi, Maryam Miri Soogh, Fahimeh Alizadeh et al.
1.00
Biofilms Candida albicans Quorum Sensing Candida glabrata Menthol

Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antibactériens › Recent progress of antibacterial natural...
questionsmedicales.fr › Mélanges complexes › Produits biologiques › Recent progress of antibacterial natural...
questionsmedicales.fr › Techniques d'investigation › Développement de médicament › Découverte de médicament › Recent progress of antibacterial natural...
questionsmedicales.fr › Techniques d'investigation › Évaluation préclinique de médicament › Tests de sensibilité microbienne › Recent progress of antibacterial natural...