Evaluation of safety and diagnostic performance for flexible hysteroscopy in 1591 outpatient cases.


Journal

Japanese journal of clinical oncology
ISSN: 1465-3621
Titre abrégé: Jpn J Clin Oncol
Pays: England
ID NLM: 0313225

Informations de publication

Date de publication:
28 Sep 2020
Historique:
received: 28 01 2020
accepted: 27 05 2020
pubmed: 22 6 2020
medline: 11 11 2020
entrez: 22 6 2020
Statut: ppublish

Résumé

To date, only few large studies are available concerning the safety and diagnostic concordance rates of outpatient flexible hysteroscopy. In our institution, outpatient hysteroscopy has been routinely and educationally applied Kosuke Tsuji to intrauterine lesions; thus, we retrospectively investigated the institution's outpatient flexible hysteroscopy cases. A total of 1591 cases of outpatient flexible hysteroscopy conducted at our institution in 2012-2016 were retrospectively analyzed in terms of their clinical background, complications and diagnostic concordance rates. A total of 1591 cases included 546 cases of benign tumors (317 endometrial polyps, 168 myomas and 61 endometrial hyperplasia), 361 cases of atypical endometrial hyperplasia, 571 cases of endometrial cancers and 113 cases of other diagnoses. No major complications, including uterine perforation, occurred. However, one patient (0.06%) was diagnosed with septic shock caused by intrauterine infection that required prolonged immunosuppressive drug administration. Meanwhile, 335 patients diagnosed with benign tumors through outpatient flexible hysteroscopy underwent operation, and the diagnostic concordance rate was 74.6% (250 cases). However, this rate included 14 cases (4.2%) diagnosed with malignant tumors postoperatively. In preoperative endometrial cancer cases, the sensitivity and specificity for cervical invasion diagnosis were 39.4 and 90.8%, respectively. In addition, only one patient manifested positive ascites cytology intraoperatively, possibly caused by outpatient hysteroscopy. Outpatient flexible hysteroscopy is highly safe, with a slight negligible effect on ascites cytology. However, the diagnosis should be determined by multidisciplinary approaches, as hysteroscopy alone can miss malignancy.

Sections du résumé

BACKGROUND BACKGROUND
To date, only few large studies are available concerning the safety and diagnostic concordance rates of outpatient flexible hysteroscopy. In our institution, outpatient hysteroscopy has been routinely and educationally applied Kosuke Tsuji to intrauterine lesions; thus, we retrospectively investigated the institution's outpatient flexible hysteroscopy cases.
METHODS METHODS
A total of 1591 cases of outpatient flexible hysteroscopy conducted at our institution in 2012-2016 were retrospectively analyzed in terms of their clinical background, complications and diagnostic concordance rates.
RESULTS RESULTS
A total of 1591 cases included 546 cases of benign tumors (317 endometrial polyps, 168 myomas and 61 endometrial hyperplasia), 361 cases of atypical endometrial hyperplasia, 571 cases of endometrial cancers and 113 cases of other diagnoses. No major complications, including uterine perforation, occurred. However, one patient (0.06%) was diagnosed with septic shock caused by intrauterine infection that required prolonged immunosuppressive drug administration. Meanwhile, 335 patients diagnosed with benign tumors through outpatient flexible hysteroscopy underwent operation, and the diagnostic concordance rate was 74.6% (250 cases). However, this rate included 14 cases (4.2%) diagnosed with malignant tumors postoperatively. In preoperative endometrial cancer cases, the sensitivity and specificity for cervical invasion diagnosis were 39.4 and 90.8%, respectively. In addition, only one patient manifested positive ascites cytology intraoperatively, possibly caused by outpatient hysteroscopy.
CONCLUSIONS CONCLUSIONS
Outpatient flexible hysteroscopy is highly safe, with a slight negligible effect on ascites cytology. However, the diagnosis should be determined by multidisciplinary approaches, as hysteroscopy alone can miss malignancy.

Identifiants

pubmed: 32564088
pii: 5860591
doi: 10.1093/jjco/hyaa098
doi:

Types de publication

Evaluation Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1157-1161

Informations de copyright

© The Author(s) 2020. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permission@oup.com.

Auteurs

Yusuke Kobayashi (Y)

Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.

Kosuke Tsuji (K)

Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.

Kanako Nakamura (K)

Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.

Shimpei Nagai (S)

Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.

Takayuki Takahashi (T)

Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.

Arata Kobayashi (A)

Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.

Mayuka Anko (M)

Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.

Takuro Hirano (T)

Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.

Keiko Watanabe (K)

Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.

Yusuke Matoba (Y)

Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.

Haruko Kunitomi (H)

Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.

Masataka Adachi (M)

Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.

Wataru Yamagami (W)

Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.

Eiichiro Tominaga (E)

Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.

Kouji Banno (K)

Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.

Daisuke Aoki (D)

Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, Japan.

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