Combined deletion of Glut1 and Glut3 impairs lung adenocarcinoma growth.

Adenocarcinoma of Lung / physiopathology Animals Cell Line, Tumor Female Fluorodeoxyglucose F18 / chemistry Gene Deletion Glucose / metabolism Glucose Transporter Type 1 / genetics Glucose Transporter Type 2 / genetics Humans Male Mice Mice, Transgenic Microscopy, Electron, Scanning Microscopy, Electron, Transmission Positron-Emission Tomography Spectrometry, Mass, Secondary Ion
NanoSIMS cancer biology genetically engineered mouse model of cancer glucose transporters human lamellar bodies lung adenocarcinoma mouse

Journal

eLife
ISSN: 2050-084X
Titre abrégé: Elife
Pays: England
ID NLM: 101579614

Informations de publication

Date de publication:
23 06 2020
Historique:
received: 14 11 2019
accepted: 05 06 2020
entrez: 24 6 2020
pubmed: 24 6 2020
medline: 17 2 2021
Statut: epublish

Résumé

Glucose utilization increases in tumors, a metabolic process that is observed clinically by

Identifiants

DOI: 10.7554/eLife.53618 PMID: 32571479 PMC: PMC7311173
pubmed: 32571479
doi: 10.7554/eLife.53618
pii: 53618
pmc: PMC7311173
doi:
pii:

Substances chimiques

Glucose Transporter Type 1 0
Glucose Transporter Type 2 0
SLC2A1 protein, human 0
SLC2A2 protein, human 0
Slc2a1 protein, mouse 0
Slc2a2 protein, mouse 0
Fluorodeoxyglucose F18 0Z5B2CJX4D
Glucose IY9XDZ35W2

Banques de données

GEO
['GSE138757']

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NCI NIH HHS
ID : R01 CA217987
Pays : United States
Organisme : Swiss Cancer Research Foundation
ID : KFS-3681-08-2015-R
Pays : International
Organisme : Swiss National Science Foundation
ID : PP00P3_157527
Pays : Switzerland
Organisme : Swiss National Science Foundation
ID : PP00P3_133661
Pays : Switzerland

Informations de copyright

© 2020, Contat et al.

Déclaration de conflit d'intérêts

CC, PA, NZ, SS, JP, SE, LJ, CG, BL, ML, RG, AR, SB, CN, IZ, SC, GK, JR, EA, AM, EM No competing interests declared

Références

Nature. 2009 Nov 5;462(7269):104-7
pubmed: 19847165
Cancer Res. 2005 Nov 15;65(22):10280-8
pubmed: 16288016
Environ Microbiol. 2012 Apr;14(4):1009-23
pubmed: 22221878
Annu Rev Cell Dev Biol. 2011;27:441-64
pubmed: 21985671
Nature. 2014 Jul 31;511(7511):543-50
pubmed: 25079552
J Nucl Med. 2014 Aug;55(8):1380-8
pubmed: 24914058
Mol Endocrinol. 2005 Sep;19(9):2335-48
pubmed: 15890673
Sci Transl Med. 2018 Nov 14;10(467):
pubmed: 30429355
Nature. 2013 May 30;497(7451):633-7
pubmed: 23665962
Cell Metab. 2014 May 6;19(5):795-809
pubmed: 24726384
FEBS J. 2018 Aug;285(16):2926-2943
pubmed: 29893496
Cell. 2016 Feb 11;164(4):681-94
pubmed: 26853473
Nat Med. 2017 Nov;23(11):1362-1368
pubmed: 28967920
Cancer Discov. 2014 Aug;4(8):914-27
pubmed: 24875857
Nature. 2014 Mar 13;507(7491):190-4
pubmed: 24499815
PLoS One. 2011;6(8):e23205
pubmed: 21826239
Sci Rep. 2017 Dec 4;7(1):16878
pubmed: 29203879
Cell. 2019 Apr 18;177(3):572-586.e22
pubmed: 30955884
Nature. 2016 Mar 3;531(7592):110-3
pubmed: 26909577
Cancer Cell. 2013 Aug 12;24(2):213-228
pubmed: 23911236
Nat Commun. 2017 May 26;8:15503
pubmed: 28548087
Proc Natl Acad Sci U S A. 2012 Mar 27;109(13):4910-5
pubmed: 22411819
Proc Natl Acad Sci U S A. 2014 Apr 1;111(13):4952-7
pubmed: 24586047
Annu Rev Nutr. 2001;21:193-230
pubmed: 11375435
Proc Natl Acad Sci U S A. 2005 Oct 25;102(43):15545-50
pubmed: 16199517
J Transl Med. 2013 Apr 30;11:104
pubmed: 23627766
Nature. 2013 Apr 4;496(7443):101-5
pubmed: 23535601
Cell Rep. 2017 Dec 12;21(11):3190-3204
pubmed: 29241546
Cell Rep. 2019 Aug 13;28(7):1860-1878.e9
pubmed: 31412252
PPAR Res. 2010;2010:
pubmed: 20936127

Auteurs

Caroline Contat (C)

Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Swiss Cancer Center Léman, Lausanne, Switzerland.

Pierre-Benoit Ancey (PB)

Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Swiss Cancer Center Léman, Lausanne, Switzerland.

Nadine Zangger (N)

Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Swiss Cancer Center Léman, Lausanne, Switzerland.
Bioinformatics Core Facility, Swiss Institute of Bioinformatics, Lausanne, Switzerland.

Silvia Sabatino (S)

Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Swiss Cancer Center Léman, Lausanne, Switzerland.

Justine Pascual (J)

Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Swiss Cancer Center Léman, Lausanne, Switzerland.

Stéphane Escrig (S)

Laboratory for Biological Geochemistry, School of Architecture, Civil and Environmental Engineering, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

Louise Jensen (L)

Laboratory for Biological Geochemistry, School of Architecture, Civil and Environmental Engineering, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

Christine Goepfert (C)

Institute of Animal Pathology (COMPATH), University of Bern, CH-3012 Bern, and Histology Core Facility, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

Bernard Lanz (B)

Laboratory for Functional and Metabolic Imaging (LIFMET), Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

Mario Lepore (M)

Center for Biomedical Imaging (CIBM), Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

Rolf Gruetter (R)

Laboratory for Functional and Metabolic Imaging (LIFMET), Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Center for Biomedical Imaging (CIBM), Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

Anouk Rossier (A)

Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Swiss Cancer Center Léman, Lausanne, Switzerland.

Sabina Berezowska (S)

Institute of Pathology, University of Bern, Bern, Switzerland.

Christina Neppl (C)

Institute of Pathology, University of Bern, Bern, Switzerland.

Inti Zlobec (I)

Institute of Pathology, University of Bern, Bern, Switzerland.

Stéphanie Clerc-Rosset (S)

BioEM Facility, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

Graham William Knott (GW)

BioEM Facility, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
ORCID: 0000-0002-2956-9052

Jeffrey C Rathmell (JC)

Vanderbilt Center for Immunobiology, Vanderbilt University Medical Center, Nashville, United States.

E Dale Abel (ED)

Fraternal Order of Eagles Diabetes Research Center and Division of Endocrinology and Metabolism, Carver College of Medicine, University of Iowa, Iowa City, United States.
ORCID: 0000-0001-5290-0738

Anders Meibom (A)

Laboratory for Biological Geochemistry, School of Architecture, Civil and Environmental Engineering, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Center for Advanced Surface Analysis, Faculty of Geosciences and Environment, University of Lausanne, Lausanne, Switzerland.

Etienne Meylan (E)

Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Swiss Cancer Center Léman, Lausanne, Switzerland.
ORCID: 0000-0002-0899-2230

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Tumeurs › Tumeurs par siège › Tumeurs du thorax › Adénocarcinome pulmonaire › Combined deletion of Glut1 and Glut3 impairs...
questionsmedicales.fr › Eucaryotes › Animaux › Combined deletion of Glut1 and Glut3 impairs...
questionsmedicales.fr › Cellules › Cellules cultivées › Cellules cancéreuses en culture › Lignée cellulaire tumorale › Combined deletion of Glut1 and Glut3 impairs...
questionsmedicales.fr › Glucides › Désoses › Désoxyglucose › Fluorodésoxyglucose F18 › Combined deletion of Glut1 and Glut3 impairs...
questionsmedicales.fr › Phénomènes génétiques › Mutagenèse › Délétion de séquence › Délétion de gène › Combined deletion of Glut1 and Glut3 impairs...
questionsmedicales.fr › Glucides › Sucres › Oses › Hexose › Glucose › Combined deletion of Glut1 and Glut3 impairs...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › Protéines transporteurs de solutés › Transporteurs de glucose par diffusion facilitée › Transporteur de glucose de type 1 › Combined deletion of Glut1 and Glut3 impairs...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › Protéines transporteurs de solutés › Transporteurs de glucose par diffusion facilitée › Transporteur de glucose de type 2 › Combined deletion of Glut1 and Glut3 impairs...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Combined deletion of Glut1 and Glut3 impairs...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Combined deletion of Glut1 and Glut3 impairs...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souris transgéniques › Combined deletion of Glut1 and Glut3 impairs...
questionsmedicales.fr › Techniques d'investigation › Microscopie électronique › Microscopie électronique à balayage › Combined deletion of Glut1 and Glut3 impairs...
questionsmedicales.fr › Techniques d'investigation › Microscopie électronique › Microscopie électronique à transmission › Combined deletion of Glut1 and Glut3 impairs...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Techniques de diagnostic radioisotopique › Scintigraphie › Tomoscintigraphie › Tomographie par émission de positons › Combined deletion of Glut1 and Glut3 impairs...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Spectrométrie de masse › Spectrométrie de masse d'ions secondaires › Combined deletion of Glut1 and Glut3 impairs...