Lidocaine spray versus viscous lidocaine solution for pharyngeal local anesthesia in upper gastrointestinal endoscopy: Systematic review and meta-analysis.


Journal

Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society
ISSN: 1443-1661
Titre abrégé: Dig Endosc
Pays: Australia
ID NLM: 9101419

Informations de publication

Date de publication:
May 2021
Historique:
received: 06 04 2020
accepted: 14 06 2020
pubmed: 24 6 2020
medline: 29 7 2021
entrez: 24 6 2020
Statut: ppublish

Résumé

There are two major methods for local anesthesia by lidocaine before upper gastrointestinal endoscopy: simple spray and viscous solution. We aimed to assess the efficacy and safety by meta-analysis between these two methods. We searched PubMed, EMBASE, the Cochrane Central Register of Controlled Trials, World Health Organization International Clinical Trials Registry Platform, and ClinicalTrials.gov databases through October 2019 to perform meta-analyses using random-effects models. The primary outcomes were participants' pain/discomfort, satisfaction, and anaphylactic shock. Three reviewers independently searched for articles, extracted data, and assessed the risk of bias. We evaluated the certainty of evidence based on the Grading of Recommendations, Assessment, Development, and Evaluation approach. This study was registered in PROSPERO (CRD42020155611). We included seven randomized controlled trials (2667 participants). The participants' pain/discomfort may be similar between the lidocaine spray and viscous solution [standardized mean difference 0.03, 95% confidence intervals (CI) -0.37 to 0.42; I The use of lidocaine spray for local anesthesia provided better satisfaction scores than the viscous solution, and both methods have the same effect with regards to the control of discomfort and pain. Further studies in large multicenter randomized controlled trials with a pre-registration protocol are needed.

Identifiants

pubmed: 32573016
doi: 10.1111/den.13775
doi:

Substances chimiques

Lidocaine 98PI200987

Types de publication

Journal Article Meta-Analysis Review Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

538-548

Informations de copyright

© 2020 Japan Gastroenterological Endoscopy Society.

Références

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Auteurs

Jun Watanabe (J)

Center for Community Medicine, Jichi Medical University, Tochigi, Japan.
Department of Surgery, Tottori Prefectural Central Hospital, Tottori, Japan.
Systematic Review Workshop Peer Support Group (SRWS-PSG), Osaka, Japan.

Yusuke Ikegami (Y)

General Internal Medicine, Minami-Nara General Medical Center, Nara, Japan.

Ayumi Tsuda (A)

Department of Surgery, Tottori Prefectural Central Hospital, Tottori, Japan.

Eiichi Kakehi (E)

Department of General Medicine, Tottori Municipal Hospital, Tottori, Japan.

Takeshi Kanno (T)

Division of Gastroenterology, Tohoku University Hospital, Miyagi, Japan.

Shizukiyo Ishikawa (S)

Center for Community Medicine, Jichi Medical University, Tochigi, Japan.

Yuki Kataoka (Y)

Systematic Review Workshop Peer Support Group (SRWS-PSG), Osaka, Japan.
Hospital Care Research Unit, Hyogo Prefectural Amagasaki General Medical Center, Hyogo, Japan.

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