The structure of the Drosophila melanogaster sex peptide: Identification of hydroxylated isoleucine and a strain variation in the pattern of amino acid hydroxylation.
Animals
Drosophila Proteins
/ chemistry
Drosophila melanogaster
/ genetics
Genes, Insect
Genetic Variation
Hydroxylation
Intercellular Signaling Peptides and Proteins
/ chemistry
Isoleucine
/ metabolism
Mixed Function Oxygenases
/ genetics
Sex Attractants
/ chemistry
Sexual Behavior, Animal
/ physiology
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
/ methods
2-Oxoglutarate-dependent oxygenase
4-Hydroxyproline
Drosophila melanogaster
Hydroxyisoleucine
Sex peptide
prolyl hydroxylase
Journal
Insect biochemistry and molecular biology
ISSN: 1879-0240
Titre abrégé: Insect Biochem Mol Biol
Pays: England
ID NLM: 9207282
Informations de publication
Date de publication:
09 2020
09 2020
Historique:
received:
11
03
2020
revised:
05
05
2020
accepted:
18
05
2020
pubmed:
27
6
2020
medline:
27
3
2021
entrez:
27
6
2020
Statut:
ppublish
Résumé
In Drosophila melanogaster mating triggers profound changes in the behaviour and reproductive physiology of the female. Many of these post-mating effects are elicited by sex peptide (SP), a 36-mer pheromone made in the male accessory gland and passed to the female in the seminal fluid. The peptide comprises several structurally and functionally distinct domains, one of which consists of five 4-hydroxyprolines and induces a female immune response. The SP gene predicts an isoleucine (Ile
Identifiants
pubmed: 32589920
pii: S0965-1748(20)30103-X
doi: 10.1016/j.ibmb.2020.103414
pii:
doi:
Substances chimiques
Drosophila Proteins
0
Intercellular Signaling Peptides and Proteins
0
Sex Attractants
0
male accessory gland peptide, Drosophila
0
Isoleucine
04Y7590D77
Mixed Function Oxygenases
EC 1.-
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
103414Informations de copyright
Copyright © 2020 Elsevier Ltd. All rights reserved.