Review of pathological findings in laparoscopic sleeve gastrectomy specimens performed for morbid obesity.


Journal

Journal of clinical pathology
ISSN: 1472-4146
Titre abrégé: J Clin Pathol
Pays: England
ID NLM: 0376601

Informations de publication

Date de publication:
Oct 2020
Historique:
received: 06 01 2020
revised: 14 04 2020
accepted: 16 04 2020
pubmed: 28 6 2020
medline: 29 9 2020
entrez: 28 6 2020
Statut: ppublish

Résumé

Bariatric surgical procedures are employed when there is a failure of lifestyle modification in arresting obesity. Laparoscopic sleeve gastrectomy (LSG) is quickly becoming the bariatric surgical procedure of choice. LSG results in a gastric remnant that is subject to pathological examination. The objective of this paper is to review the literature in regard to histological findings identified in gastric remnants post-LSG and identify the most pertinent histological findings. A literature search was performed to identify relevant case series. Data gathered from relevant case series then underwent statistical analysis. The most common histological findings in an LSG specimen were clinically indolent findings such as no pathological abnormalities identified followed by non-specific gastritis. A minority of cases demonstrated clinically actionable findings for which There is a broad spectrum of pathological findings in LSG specimens, ranging from clinically indolent to clinically actionable. The most common histological findings are clinically indolent and only a small portion are of clinical significance and, hence, actionable.

Sections du résumé

BACKGROUND BACKGROUND
Bariatric surgical procedures are employed when there is a failure of lifestyle modification in arresting obesity. Laparoscopic sleeve gastrectomy (LSG) is quickly becoming the bariatric surgical procedure of choice. LSG results in a gastric remnant that is subject to pathological examination. The objective of this paper is to review the literature in regard to histological findings identified in gastric remnants post-LSG and identify the most pertinent histological findings.
MATERIALS AND METHODS METHODS
A literature search was performed to identify relevant case series. Data gathered from relevant case series then underwent statistical analysis.
RESULTS RESULTS
The most common histological findings in an LSG specimen were clinically indolent findings such as no pathological abnormalities identified followed by non-specific gastritis. A minority of cases demonstrated clinically actionable findings for which
CONCLUSION CONCLUSIONS
There is a broad spectrum of pathological findings in LSG specimens, ranging from clinically indolent to clinically actionable. The most common histological findings are clinically indolent and only a small portion are of clinical significance and, hence, actionable.

Identifiants

pubmed: 32591353
pii: jclinpath-2020-206428
doi: 10.1136/jclinpath-2020-206428
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

618-623

Informations de copyright

© Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Auteurs

Klaudia Nowak (K)

Department of Pathology, University Health Network Laboratory Medicine Program, University of Toronto, Toronto, Ontario, Canada.

Adam DiPalma (A)

Department of General Surgery, University Health Network and University of Toronto, Toronto, Ontario, Canada.

Stefano Serra (S)

Department of Pathology, University Health Network Laboratory Medicine Program, University of Toronto, Toronto, Ontario, Canada.

Fayez Quereshy (F)

Department of General Surgery, University Health Network and University of Toronto, Toronto, Ontario, Canada.

Timothy Jackson (T)

Department of General Surgery, University Health Network and University of Toronto, Toronto, Ontario, Canada.

Allan Okrainec (A)

Department of General Surgery, University Health Network and University of Toronto, Toronto, Ontario, Canada.

Runjan Chetty (R)

Department of Pathology, University Health Network Laboratory Medicine Program, University of Toronto, Toronto, Ontario, Canada runjan.chetty@gmail.com.

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