Resection of Bronchogenic Cysts in Symptomatic Versus Asymptomatic Patients: An Outcome Analysis.


Journal

The Annals of thoracic surgery
ISSN: 1552-6259
Titre abrégé: Ann Thorac Surg
Pays: Netherlands
ID NLM: 15030100R

Informations de publication

Date de publication:
11 2021
Historique:
received: 26 07 2019
revised: 19 04 2020
accepted: 01 05 2020
pubmed: 1 7 2020
medline: 11 11 2021
entrez: 30 6 2020
Statut: ppublish

Résumé

The natural evolution of bronchogenic cysts (BCs) is unpredictable. Although most surgeons agree that symptomatic BCs should be resected, questions remain regarding the optimal management of asymptomatic mediastinal cysts. We present a case series of BCs to compare patients who underwent preventive operation with those who underwent surgical procedure after symptom onset. This 15-year multicenter retrospective study included 114 patients (32 children and 82 adults). Data on clinical history, pathology, mean hospital stay, intraoperative and postoperative complications, and associated intraoperative procedures were analyzed separately for symptomatic and asymptomatic patients. A total of 53 asymptomatic patients (46.5%) were compared with 61 symptomatic patients (53.5%). There were significantly more adults in the symptomatic group than in the asymptomatic group (48 vs 34 patients, P < .05). A thoracoscopic approach was used in 88 patients (77%), with 7 conversions to thoracotomy (9%), all in symptomatic patients. There were significantly more additional procedures (20% vs 4%, P = .01) and more intraoperative complications (20% vs 4%, P = .01) in symptomatic patients, but postoperative complications between symptomatic and asymptomatic patients were similar. The postoperative length of stay was significantly longer in symptomatic patients (5.71 days vs 4 days, P < .001). Pathologic examination found significantly more inflammatory reactions in symptomatic patients. Early surgical management of BCs may be recommended to prevent symptomatic complications, which are unpredictable and whose management is more complicated in advanced BCs. Surgery can be performed with a thoracoscopic approach, which is easier and safer when the cyst is small and uncomplicated.

Sections du résumé

BACKGROUND
The natural evolution of bronchogenic cysts (BCs) is unpredictable. Although most surgeons agree that symptomatic BCs should be resected, questions remain regarding the optimal management of asymptomatic mediastinal cysts. We present a case series of BCs to compare patients who underwent preventive operation with those who underwent surgical procedure after symptom onset.
METHODS
This 15-year multicenter retrospective study included 114 patients (32 children and 82 adults). Data on clinical history, pathology, mean hospital stay, intraoperative and postoperative complications, and associated intraoperative procedures were analyzed separately for symptomatic and asymptomatic patients.
RESULTS
A total of 53 asymptomatic patients (46.5%) were compared with 61 symptomatic patients (53.5%). There were significantly more adults in the symptomatic group than in the asymptomatic group (48 vs 34 patients, P < .05). A thoracoscopic approach was used in 88 patients (77%), with 7 conversions to thoracotomy (9%), all in symptomatic patients. There were significantly more additional procedures (20% vs 4%, P = .01) and more intraoperative complications (20% vs 4%, P = .01) in symptomatic patients, but postoperative complications between symptomatic and asymptomatic patients were similar. The postoperative length of stay was significantly longer in symptomatic patients (5.71 days vs 4 days, P < .001). Pathologic examination found significantly more inflammatory reactions in symptomatic patients.
CONCLUSION
Early surgical management of BCs may be recommended to prevent symptomatic complications, which are unpredictable and whose management is more complicated in advanced BCs. Surgery can be performed with a thoracoscopic approach, which is easier and safer when the cyst is small and uncomplicated.

Identifiants

pubmed: 32599038
pii: S0003-4975(20)30969-3
doi: 10.1016/j.athoracsur.2020.05.031
pii:
doi:

Types de publication

Comparative Study Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

1553-1558

Informations de copyright

Copyright © 2021 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

Auteurs

Lucile Fievet (L)

Department of Pediatric Surgery, Centre Hospitalier Régional Henri Duffaut, Provence-Alpes-Côte d'Azur, Avignon, France. Electronic address: fievet.lucile@ch-avignon.fr.

Dominique Gossot (D)

Department of Thoracic Surgery, Institut Mutaliste Montsouris, Île de France, Paris, France.

Henri de Lesquen (H)

Department of Thoracic Surgery, North Hospital, Assistance Publique-Hôpitaux de Marseille, Provence-Alpes-Côte d'Azur, Marseille, France.

Charline Calabre (C)

Department of Pediatric Surgery, Centre Hospitalier Régional Universitaire Strasbourg, Alsace, France.

Thierry Merrot (T)

Department of Pediatric Surgery, La Timone Hospital, Assistance Publique-Hôpitaux de Marseille, Provence-Alpes-Côte d'Azur, Marseille, France.

Pascal Thomas (P)

Department of Thoracic Surgery, North Hospital, Assistance Publique-Hôpitaux de Marseille, Provence-Alpes-Côte d'Azur, Marseille, France.

François Becmeur (F)

Department of Pediatric Surgery, Centre Hospitalier Régional Universitaire Strasbourg, Alsace, France.

Madalina Grigoroiu (M)

Department of Thoracic Surgery, Institut Mutaliste Montsouris, Île de France, Paris, France.

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