Patient-Centric Head and Neck Cancer Radiation Therapy: Role of Advanced Imaging.

Diagnostic Imaging / methods Head and Neck Neoplasms / diagnostic imaging Humans Radiotherapy Planning, Computer-Assisted / methods Radiotherapy, Conformal
Advanced imaging Functional imaging Head and neck cancer Individualized Personalized Radiation planning Tumor hypoxia

Journal

Neuroimaging clinics of North America
ISSN: 1557-9867
Titre abrégé: Neuroimaging Clin N Am
Pays: United States
ID NLM: 9211377

Informations de publication

Date de publication:
Aug 2020
Historique:
entrez: 1 7 2020
pubmed: 1 7 2020
medline: 27 4 2021
Statut: ppublish

Résumé

The traditional 'one-size-fits-all' approach to H&N cancer therapy is archaic. Advanced imaging can identify radioresistant areas by using biomarkers that detect tumor hypoxia, hypercellularity etc. Highly conformal radiotherapy can target resistant areas with precision. The critical information that can be gleaned about tumor biology from these advanced imaging modalities facilitates individualized radiotherapy. The tumor imaging world is pushing its boundaries. Molecular imaging can now detect protein expression and genotypic variations across tumors that can be exploited for tailoring treatment. The exploding field of radiomics and radiogenomics extracts quantitative, biologic and genetic information and further expands the scope of personalized therapy.

Identifiants

DOI: 10.1016/j.nic.2020.04.005 PMID: 32600635
pubmed: 32600635
pii: S1052-5149(20)30028-9
doi: 10.1016/j.nic.2020.04.005
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

341-357

Informations de copyright

Copyright © 2020 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Disclosure R. Forghani has acted as speaker and consultant for GE Healthcare and has a research agreement (beta tester) and research support from GE Healthcare. R. Forghani is also a founder and stockholder of 4intelligent Inc.

Auteurs

Monica Shukla (M)

Department of Radiation Oncology, Froedtert and Medical College of Wisconsin, 9200 W. Wisconsin Avenue, Milwaukee, WI 53226, USA.

Reza Forghani (R)

Augmented Intelligence & Precision Health Laboratory, Department of Radiology, Research Institute of McGill University Health Centre, 1001 Decarie Boulevard, Montreal, Quebec H4A 3J1, Canada.

Mohit Agarwal (M)

Department of Radiology, Section of Neuroradiology, Froedtert and Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA. Electronic address: magarwal@mcw.edu.

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Classifications MeSH

questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Imagerie diagnostique › Patient-Centric Head and Neck Cancer Radiation...
questionsmedicales.fr › Tumeurs › Tumeurs par siège › Tumeurs de la tête et du cou › Patient-Centric Head and Neck Cancer Radiation...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Patient-Centric Head and Neck Cancer Radiation...
questionsmedicales.fr › Sciences de l'information › Informatique › Informatique médicale › Applications de l'informatique médicale › Prise de décision assistée par ordinateur › Thérapie assistée par ordinateur › Radiothérapie assistée par ordinateur › Planification de radiothérapie assistée par ordinateur › Patient-Centric Head and Neck Cancer Radiation...
questionsmedicales.fr › Sciences de l'information › Informatique › Informatique médicale › Applications de l'informatique médicale › Prise de décision assistée par ordinateur › Thérapie assistée par ordinateur › Radiothérapie assistée par ordinateur › Radiothérapie conformationnelle › Patient-Centric Head and Neck Cancer Radiation...