Effects of Zinc Oxide/Zeolite on Intestinal Morphology, Intestinal Microflora, and Diarrhea Rates in Weaned Piglets.
Diarrhea
Intestinal microflora
Intestinal morphology
Weaned piglets
Zinc oxide/zeolite
Journal
Biological trace element research
ISSN: 1559-0720
Titre abrégé: Biol Trace Elem Res
Pays: United States
ID NLM: 7911509
Informations de publication
Date de publication:
Apr 2021
Apr 2021
Historique:
received:
15
05
2020
accepted:
17
06
2020
pubmed:
2
7
2020
medline:
22
6
2021
entrez:
2
7
2020
Statut:
ppublish
Résumé
This experiment was conducted to investigate the effects of zinc oxide/zeolite on growth performance, serum biochemistry, intestinal morphology, and microflora of weaned piglets. Two hundred and fifty-six weaned piglets (Duroc × Landrace × Large) at 21 days of age were randomly assigned to 2 groups with 8 replicates and 16 piglets in each pen. The diets of high dose of zinc oxide group (HD-ZnO) supplemented with 1500 mg/kg zinc as zinc oxide, but the diet of experimental group supplemented with 500 mg/kg zinc as zinc oxide that supported on zeolite (SR-ZnO). The experiment was conducted for 2 weeks after weanling. The results showed replacement of high-dosed zinc oxide by SR-ZnO had no significant effects on growth performance and intestinal morphology. However, the dietary supplementation of SR-ZnO reduced the diarrhea rate (P < 0.05), increased the activity of serum alkaline phosphatase (ALP) (P < 0.01), and tended to reduce zinc release in stomach (P = 0.06) and increase serum total protein (TP) (P = 0.07). Although there were no significant effects in ileal microflora on α diversity, the abundance of Campylobacters was found significantly decreased (P < 0.05), whereas the abundance of Clostridium was increased (P < 0.05) after lower-dosed SR-ZnO replacement. It is revealed that replacement of HD-ZnO (1500 mg/kg) by SR-ZnO (500 mg/kg) in creep feed could improve the zinc bioavailability, regulate the intestinal flora, and alleviate the postweaning diarrhea in weaned piglets. Accordingly, the application of SR-ZnO would reduce the zinc in feed and therefore benefits for the ecological environment.
Identifiants
pubmed: 32607765
doi: 10.1007/s12011-020-02262-0
pii: 10.1007/s12011-020-02262-0
doi:
Substances chimiques
Zeolites
1318-02-1
Zinc Oxide
SOI2LOH54Z
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1405-1413Subventions
Organisme : National Key R&D Program of China
ID : 2016YFD0501201
Organisme : Young Scientists Fund
ID : 31702127
Organisme : the Young Elite Scientists Sponsorship Program by CAST
ID : 2018QNRC001
Organisme : Hunan Province Key Laboratory of Animal Nutritional Physiology and Metabolic Process
ID : 2018TP1031
Organisme : Science and Technology Service Network Plan (CN)
ID : KFJ-STS-QYZD-095
Organisme : Yangzhou Science and Technology Bureau-Modern Agricultural Technology Project
ID : SNY2017030037
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