Debate on Selection Criteria for Liver Transplantation for Alcoholic Hepatitis: Tighten or Loosen?


Journal

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
ISSN: 1527-6473
Titre abrégé: Liver Transpl
Pays: United States
ID NLM: 100909185

Informations de publication

Date de publication:
07 2020
Historique:
received: 09 01 2020
revised: 17 03 2020
accepted: 12 04 2020
entrez: 3 7 2020
pubmed: 3 7 2020
medline: 19 3 2021
Statut: ppublish

Résumé

Although liver transplantation (LT) for alcohol-associated liver disease (ALD) is a well-accepted practice, LT for severe alcoholic hepatitis (AH) remains controversial due to concerns about the limited organ supply and the risk of return to harmful drinking. Recognizing an increasing body of favorable evidence, a convergence of practice guideline recommendations from leading hepatology and gastroenterology societies have suggested that the length of abstinence should not be a sole criterion for LT selection and, thus, that LT may be considered in carefully selected severe AH patients with favorable psychosocial profiles not responding to medical therapy. We sought to examine this new consensus in greater detail, debating whether candidate selection criteria for LT in AH should be tightened or loosened.

Identifiants

pubmed: 32614520
doi: 10.1002/lt.25783
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

916-921

Informations de copyright

Copyright © 2020 by the American Association for the Study of Liver Diseases.

Références

Kumar S, Stauber RE, Gavaler JS, Basista MH, Dindzans VJ, Schade RR, et al. Orthotopic liver transplantation for alcoholic liver disease. Hepatology 1990;11:159-164.
Madden S, Lucey MR, Neuberger J. Does Publicity affect Organ Donation? Transpl Int; https://doi.org/10.1111/tri.13655.
Wong E, Mullins PD, Wallach JP, Yoshida EM, Erb SR, Ford JA, et al. Patients' perspectives on early liver transplantation in alcohol-related liver disease. Hepatol Commun 2019;3:1022-1031.
Rowe IA, Webb K, Gunson BK, Mehta N, Haque S, Neuberger J. The impact of disease recurrence on graft survival following liver transplantation: a single centre experience. Transpl Int 2008;21:459-465.
Rice JP, Eickhoff J, Agni R, Ghufran A, Brahmbhatt R, Lucey MR. Abusive drinking after liver transplantation is associated with allograft loss and advanced allograft fibrosis. Liver Transpl 2013;19:1377-1386.
Im GY, Cameron AM, Lucey MR. Liver transplantation for alcoholic hepatitis. J Hepatol 2019;70:328-334.
Everhart JE, Beresford TP. Liver transplantation for alcoholic liver disease: a survey of transplantation programs in the United States. Liver Transpl Surg 1997;3:220-226.
Lucey MR. Liver transplantation for alcoholic liver disease. Nat Rev Gastroenterol Hepatol 2014;11:300-307.
Mathurin P, Moreno C, Samuel D, Dumortier J, Salleron J, Durand F, et al. Early liver transplantation for severe alcoholic hepatitis. N Engl J Med 2011;365:1790-1800.
Im GY, Kim-Schluger L, Shenoy A, Schubert E, Goel A, Friedman SL, et al. Early liver transplantation for severe alcoholic hepatitis in the United States-a single-center experience. Am J Transplant 2016;16:841-846.
Lee BP, Mehta N, Platt L, Gurakar A, Rice JP, Lucey MR, et al. Outcomes of early liver transplantation for patients with severe alcoholic hepatitis. Gastroenterology 2018;155:422-430.
Crabb DW, Im GY, Szabo G, Mellinger JL, Lucey MR. Diagnosis and treatment of alcohol-associated liver diseases: 2019 practice guidance from the American Association for the Study of Liver Diseases. Hepatology 2020;71:306-333.
European Association for the Study of the Liver. EASL Clinical Practice Guidelines: management of alcohol-related liver disease. J Hepatol 2018;69:154-181.
Singal AK, Bataller R, Ahn J, Kamath PS, Shah VH. ACG clinical guideline: alcoholic liver disease. Am J Gastroenterol 2018;113:175-194.
Arab JP, Roblero JP, Altamirano J, Bessone F, Chaves Araujo R, Higuera-De la Tijera F, et al. Alcohol-related liver disease: clinical practice guidelines by the Latin American Association for the Study of the Liver (ALEH). Ann Hepatol 2019;18:518-535.
Tapper EB, Parikh ND. Mortality due to cirrhosis and liver cancer in the United States, 1999-2016: observational study. BMJ 2018;362:k2817.
Cowley LE, Farewell DM, Maguire S, Kemp AM. Methodological standards for the development and evaluation of clinical prediction rules: a review of the literature. Diagn Progn Res 2019;3:16.
Glare P, Virik K, Jones M, Hudson M, Eychmuller S, Simes J, Christakis N. A systematic review of physicians' survival predictions in terminally ill cancer patients. BMJ 2003;327:195-198.
Ouchi K, Strout T, Haydar S, Baker O, Wang W, Bernacki R, et al. Association of emergency clinicians' assessment of mortality risk with actual 1-month mortality among older adults admitted to the hospital. JAMA Netw Open 2019;2:e1911139.
Šimundić AM. Measures of diagnostic accuracy: basic definitions. EJIFCC 2009;19:203-211.
Sandahl TD, Jepsen P, Ott P, Vilstrup H. Validation of prognostic scores for clinical use in patients with alcoholic hepatitis. Scand J Gastroenterol 2011;46:1127-1132.
Chuncharunee L, Yamashiki N, Thakkinstian A, Sobhonslidsuk A. Alcohol relapse and its predictors after liver transplantation for alcoholic liver disease: a systematic review and meta-analysis. BMC Gastroenterol 2019;19:150.
Lee BP, Terrault NA. Early liver transplantation for severe alcoholic hepatitis: moving from controversy to consensus. Curr Opin Organ Transplant 2018;23:229-236.
Louvet A, Naveau S, Abdelnour M, Ramond MJ, Diaz E, Fartoux L, et al. The Lille model: a new tool for therapeutic strategy in patients with severe alcoholic hepatitis treated with steroids. Hepatology 2007;45:1348-1354.
Neuberger J, Armstrong MJ, Fisher J, Mark P, Schmidtke K, et al. Sport and exercise in improving outcomes after solid organ transplantation: overview from a UK meeting. Transplantation 2019;103(suppl 1):S1-S11.
Kim WR, Lake JR, Smith JM, Schladt DP, Skeans MA, Noreen SM, et al. OPTN/SRTR 2017 annual data report: liver. Am J Transplant 2019;19(suppl 2):184-283.
Median MELD at transplant by 250 nautical mile circles around liver transplant programs and median PELD at transplant within the nation. https://optn.transplant.hrsa.gov/media/3181/median-meld-circles-reference_09_2019.pdf. Accessed March 16, 2020.
Im GY, Lucey MR. Practical concerns and controversies in the management of alcoholic hepatitis. Gastroenterol Hepatol (N Y) 2016;12:478-489.
Crabb DW, Bataller R, Chalasani NP, Kamath PS, Lucey M, Mathurin P, et al.; for NIAA Alcoholic Hepatitis Consortia. Standard definitions and common data elements for clinical trials in patients with alcoholic hepatitis: recommendation from the NIAAA alcoholic hepatitis consortia. Gastroenterology 2016;150:785-790.
Yates WR, Labrecque DR, Pfab D. The reliability of alcoholism history in patients with alcohol-related cirrhosis. Alcohol 1998;33:488-494.
Ursic-Bedoya J, Faure S, Donnadieu-Rigole H, Pageaux GP. Liver transplantation for alcoholic liver disease: lessons learned and unresolved issues. World J Gastroenterol 2015;21:10994-11002.
Asrani SK, Trotter J, Lake J, Ahmed A, Bonagura A, Cameron A, et al. Meeting report: the Dallas consensus conference on liver transplantation for alcohol related hepatitis. Liver Transpl 2020;26:127-140.
Lee BP, Vittinghoff E, Hsu C, Han H, Therapondos G, Fix OK, et al. Predicting low risk for sustained alcohol use after early liver transplant for acute alcoholic hepatitis: the sustained alcohol use post-liver transplant score. Hepatology 2019;69:1477-1487.
Erard-Poinsot D, Dharancy S, Hilleret MN, Faure S, Lamblin G, Chambon-Augoyard C, et al. Natural history of recurrent alcohol-related cirrhosis after liver transplantation: fast and furious. Liver Transpl 2020;26:25-33.
Burra P, Germani G, Gnoato F, Lazzaro S, Russo FP, Cillo U, Senzolo M. Adherence in liver transplant recipients. Liver Transpl 2011;17:760-770.
Thursz M, Allison M. Liver transplantation for alcoholic hepatitis: being consistent about where to set the bar. Liver Transpl 2018;24:733-734.
Beresford TP, Lucey MR. Towards standardizing the alcoholism evaluation of potential liver transplant recipients. Alcohol 2018;53:135-144.
Donnadieu-Rigole H, Jaubert L, Ursic-Bedoya J, Hanslik B, Mura T, Gamon L, et al. Integration of an addiction team in a liver transplantation center. Liver Transpl 2019;25:1611-1619.
Moos RH, Moos BS. Rates and predictors of relapse after natural and treated remission from alcohol use disorders. Addiction 2006;101:212-222.
DiMartini A, Dew MA, Day N, Fitzgerald MG, Jones BL, deVera ME, Fontes P. Trajectories of alcohol consumption following liver transplantation. Am J Transplant 2010;10:2305-2312.

Auteurs

Gene Y Im (GY)

Division of Liver Diseases, Recanati/Miller Transplantation Institute, Icahn School of Medicine at Mount Sinai, New York, NY.

James Neuberger (J)

Liver Unit, Queen Elizabeth Hospital, Birmingham, United Kingdom.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH