Atypical MOG antibody disease presenting with typical multiple sclerosis lesions.
Journal
Multiple sclerosis and related disorders
ISSN: 2211-0356
Titre abrégé: Mult Scler Relat Disord
Pays: Netherlands
ID NLM: 101580247
Informations de publication
Date de publication:
Sep 2020
Sep 2020
Historique:
received:
27
05
2020
revised:
25
06
2020
accepted:
25
06
2020
pubmed:
3
7
2020
medline:
15
5
2021
entrez:
3
7
2020
Statut:
ppublish
Résumé
Myelin oligodendrocyte glycoprotein (MOG) antibody disease is an autoimmune disease of the central nervous system associated with a serological antibody against MOG, a glycoprotein expressed on the outer membrane of myelin. It is solely found within the central nervous system in the brain, optic nerves and spinal cord. MOG antibody disease falls within the neuromyelitis optica spectrum disorders (NMOSD), however clinical characteristics appear distinct from aquaporin-4 antibody related disease and multiple sclerosis. It has predilection for causing recurrent optic neuritis and transverse myelitis. Accurate diagnosis is important to determine long term prognosis and suitable treatment. We describe the case of a 42 year old woman previously labelled as MS who demonstrated a variable presentation of MOG antibody disease.
Identifiants
pubmed: 32615531
pii: S2211-0348(20)30418-1
doi: 10.1016/j.msard.2020.102342
pii:
doi:
Substances chimiques
Aquaporin 4
0
Autoantibodies
0
Myelin-Oligodendrocyte Glycoprotein
0
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
102342Informations de copyright
Copyright © 2020 Elsevier B.V. All rights reserved.