Increased Risk of Myocardial Infarction Among Patients With Type 2 Diabetes Who Carry the Common rs10830963 Variant in the
Adult
Aged
Alleles
Cohort Studies
Diabetes Mellitus, Type 2
/ complications
Diabetic Angiopathies
/ epidemiology
Female
Follow-Up Studies
Gene Frequency
Genetic Association Studies
Genetic Predisposition to Disease
Humans
Incidence
Male
Middle Aged
Myocardial Infarction
/ epidemiology
Polymorphism, Single Nucleotide
Receptor, Melatonin, MT2
/ genetics
Risk Factors
United Kingdom
/ epidemiology
Journal
Diabetes care
ISSN: 1935-5548
Titre abrégé: Diabetes Care
Pays: United States
ID NLM: 7805975
Informations de publication
Date de publication:
09 2020
09 2020
Historique:
received:
13
03
2020
accepted:
12
05
2020
pubmed:
4
7
2020
medline:
14
4
2021
entrez:
4
7
2020
Statut:
ppublish
Résumé
The common Data from the UK Biobank cohort were used in order to examine the association between rs10830963 and incidence of MCI (fatal and nonfatal) among 13,655 participants with probable T2D during a follow-up period of 6.8 years. Assuming an additive genetic model, a positive association was found between the rs10830963 variant in the The rs10830963 polymorphism may be a useful genetic marker for MCI in patients with T2D.
Identifiants
pubmed: 32616615
pii: dc20-0507
doi: 10.2337/dc20-0507
pmc: PMC7440907
doi:
Substances chimiques
MTNR1B protein, human
0
Receptor, Melatonin, MT2
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
2289-2292Subventions
Organisme : Medical Research Council
ID : MC_PC_17228
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_QA137853
Pays : United Kingdom
Informations de copyright
© 2020 by the American Diabetes Association.
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