Accurate reconstructions of pelvic defects and discontinuities using statistical shape models.


Journal

Computer methods in biomechanics and biomedical engineering
ISSN: 1476-8259
Titre abrégé: Comput Methods Biomech Biomed Engin
Pays: England
ID NLM: 9802899

Informations de publication

Date de publication:
Oct 2020
Historique:
pubmed: 4 7 2020
medline: 21 11 2020
entrez: 4 7 2020
Statut: ppublish

Résumé

Treatment of large acetabular defects and discontinuities remains challenging and relies on the accurate restoration of the native anatomy of the patient. This study introduces and validates a statistical shape model for the reconstruction of acetabular discontinuities with severe bone loss through a two-sided Markov Chain Monte Carlo reconstruction method. The performance of the reconstruction algorithm was evaluated using leave-one-out cross-validation in three defect types with varying severity as well as severe defects with discontinuities. The two-sided reconstruction method was compared to a one-sided methodology. Although, reconstruction errors increased with defect size and this increase was most pronounced for pelvic discontinuities, the two-sided reconstruction method was able to reconstruct the native anatomy with higher accuracy than the one-sided reconstruction method. These findings can improve the preoperative planning and custom implant design in patients with large pelvic defects, both with and without discontinuities.

Identifiants

pubmed: 32619099
doi: 10.1080/10255842.2020.1784404
pmc: PMC7643466
mid: NIHMS1641078
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1026-1033

Subventions

Organisme : NIDCR NIH HHS
ID : R01 DE027023
Pays : United States

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Auteurs

Alexander Meynen (A)

Institute for Orthopaedic Research and Training (IORT), Department of Development and Regeneration, Faculty of Medicine, KU Leuven, Leuven, Belgium.
Division of Orthopaedics, University Hospitals Leuven, Leuven, Belgium.

Harold Matthews (H)

Department of Human Genetics, Faculty of Medicine, KU Leuven, Leuven, Belgium.
OMFS-IMPATH Research Group, Department of Imaging and Pathology, Faculty of Medicine, KU Leuven, Leuven, Belgium.
Medical Imaging Research Center, University Hospitals Leuven, Leuven, Belgium.
Facial Sciences Research Group, Murdoch Children's Research Institute, Melbourne, Australia.

Nele Nauwelaers (N)

Department of Human Genetics, Faculty of Medicine, KU Leuven, Leuven, Belgium.
Medical Imaging Research Center, University Hospitals Leuven, Leuven, Belgium.
Department of Electrical Engineering ESAT/PSI, KU Leuven, Leuven, Belgium.

Peter Claes (P)

Department of Human Genetics, Faculty of Medicine, KU Leuven, Leuven, Belgium.
Medical Imaging Research Center, University Hospitals Leuven, Leuven, Belgium.
Facial Sciences Research Group, Murdoch Children's Research Institute, Melbourne, Australia.
Department of Electrical Engineering ESAT/PSI, KU Leuven, Leuven, Belgium.

Michiel Mulier (M)

Institute for Orthopaedic Research and Training (IORT), Department of Development and Regeneration, Faculty of Medicine, KU Leuven, Leuven, Belgium.
Division of Orthopaedics, University Hospitals Leuven, Leuven, Belgium.

Lennart Scheys (L)

Institute for Orthopaedic Research and Training (IORT), Department of Development and Regeneration, Faculty of Medicine, KU Leuven, Leuven, Belgium.
Division of Orthopaedics, University Hospitals Leuven, Leuven, Belgium.

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