Genetic Anomalies of Growth Hormone Deficiency in Pediatrics.
Hormone deficiency
genetic anomalies
genetic defects
growth hormone
pediatrics
pituitary disease
Journal
Endocrine, metabolic & immune disorders drug targets
ISSN: 2212-3873
Titre abrégé: Endocr Metab Immune Disord Drug Targets
Pays: United Arab Emirates
ID NLM: 101269157
Informations de publication
Date de publication:
2021
2021
Historique:
received:
21
12
2019
revised:
27
03
2020
accepted:
15
05
2020
pubmed:
6
7
2020
medline:
27
10
2021
entrez:
5
7
2020
Statut:
ppublish
Résumé
Several different proteins regulate, directly or indirectly, the production of growth hormones from the pituitary gland, thereby complex genetics is involved. Defects in these genes are related to the deficiency of growth hormones solely, or deficiency of other hormones, secreted from the pituitary gland including growth hormones. These studies can aid clinicians to trace the pattern of the disease between the families, start early treatment and predict possible future consequences. This paper highlights some of the most common and novel genetic anomalies concerning growth hormones, which are responsible for various genetic defects in isolated growth and combined pituitary hormone deficiency disease.
Identifiants
pubmed: 32621723
pii: EMIDDT-EPUB-107903
doi: 10.2174/1871530320666200704144912
doi:
Substances chimiques
Human Growth Hormone
12629-01-5
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
288-297Informations de copyright
Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.